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GrpEL Antibodies

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a unique system for rapid identification of GrpEL Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.

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BEZEICHNUNGKATALOG #ISOTYPEPITOPANWENDUNGENREAKTIVITÄTReferenzenBEWERTUNG
GrpEL1 (D-15)
sc-242966Ziege IgGInternal (h)WB, IP, IF, ELISAm, r, hNEW
GrpEL2 (P-13)
sc-164555Ziege IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, c, b
GrpEL2 (T-14)
sc-164556Ziege IgGN-terminal (h)WB, IF, ELISAm, r, hNEW
GrpEL2 (Y-14)
sc-164557Ziege IgGInternal (h)WB, IP, IF, ELISAm, r, h

GrpEL CRISPR Knockout, HDR and Nickase Knockout Plasmids include:

BEZEICHNUNGKATALOG #REAKTIVITÄTANWENDUNGENMARKERReferenzen
GrpEL2 CRISPR/Cas9 KO Plasmid (h)
sc-408498HumanGene KnockoutGFPNEW
GrpEL2 HDR Plasmid (h)
sc-408498-HDRHumanHomology Directed RepairPuromycinNEW
GrpEL2 Double Nickase Plasmid (h)
sc-408498-NICHumanGene KnockoutPuromycinNEW
GrpEL2 Double Nickase Plasmid (h2)
sc-408498-NIC-2HumanGene KnockoutPuromycinNEW
GrpEL1 CRISPR/Cas9 KO Plasmid (h)
sc-413374HumanGene KnockoutGFPNEW
GrpEL1 HDR Plasmid (h)
sc-413374-HDRHumanHomology Directed RepairPuromycinNEW
GrpEL1 Double Nickase Plasmid (h)
sc-413374-NICHumanGene KnockoutPuromycinNEW
GrpEL1 Double Nickase Plasmid (h2)
sc-413374-NIC-2HumanGene KnockoutPuromycinNEW
GrpEL1 CRISPR/Cas9 KO Plasmid (m)
sc-421728MausGene KnockoutGFPNEW
GrpEL1 HDR Plasmid (m)
sc-421728-HDRMausHomology Directed RepairPuromycinNEW
GrpEL1 Double Nickase Plasmid (m)
sc-421728-NICMausGene KnockoutPuromycinNEW
GrpEL1 Double Nickase Plasmid (m2)
sc-421728-NIC-2MausGene KnockoutPuromycinNEW
GrpEL2 CRISPR/Cas9 KO Plasmid (m)
sc-421729MausGene KnockoutGFPNEW
GrpEL2 HDR Plasmid (m)
sc-421729-HDRMausHomology Directed RepairPuromycinNEW
GrpEL2 Double Nickase Plasmid (m)
sc-421729-NICMausGene KnockoutPuromycinNEW
GrpEL2 Double Nickase Plasmid (m2)
sc-421729-NIC-2MausGene KnockoutPuromycinNEW

Folgende GrpEL CRISPR ACT Plasmide werden angeboten:

BEZEICHNUNGKATALOG #REAKTIVITÄTANWENDUNGENMARKERReferenzen
GrpEL2 CRISPR Activation Plasmid (h)
sc-408498-ACTHumanGene ActivationZeo, Blast, HygroNEW
GrpEL2 CRISPR Activation Plasmid (h2)
sc-408498-ACT-2HumanGene ActivationZeo, Blast, HygroNEW
GrpEL2 Lentiviral Activation Particles (h)
sc-408498-LACHumanGene ActivationZeo, Blast, HygroNEW
GrpEL2 Lentiviral Activation Particles (h2)
sc-408498-LAC-2HumanGene ActivationZeo, Blast, HygroNEW
GrpEL1 CRISPR Activation Plasmid (h)
sc-413374-ACTHumanGene ActivationZeo, Blast, HygroNEW
GrpEL1 CRISPR Activation Plasmid (h2)
sc-413374-ACT-2HumanGene ActivationZeo, Blast, HygroNEW
GrpEL1 Lentiviral Activation Particles (h)
sc-413374-LACHumanGene ActivationZeo, Blast, HygroNEW
GrpEL1 Lentiviral Activation Particles (h2)
sc-413374-LAC-2HumanGene ActivationZeo, Blast, HygroNEW
GrpEL1 CRISPR Activation Plasmid (m)
sc-421728-ACTMausGene ActivationZeo, Blast, HygroNEW
GrpEL1 CRISPR Activation Plasmid (m2)
sc-421728-ACT-2MausGene ActivationZeo, Blast, HygroNEW
GrpEL1 Lentiviral Activation Particles (m)
sc-421728-LACMausGene ActivationZeo, Blast, HygroNEW
GrpEL1 Lentiviral Activation Particles (m2)
sc-421728-LAC-2MausGene ActivationZeo, Blast, HygroNEW
GrpEL2 CRISPR Activation Plasmid (m)
sc-421729-ACTMausGene ActivationZeo, Blast, HygroNEW
GrpEL2 CRISPR Activation Plasmid (m2)
sc-421729-ACT-2MausGene ActivationZeo, Blast, HygroNEW
GrpEL2 Lentiviral Activation Particles (m)
sc-421729-LACMausGene ActivationZeo, Blast, HygroNEW
GrpEL2 Lentiviral Activation Particles (m2)
sc-421729-LAC-2MausGene ActivationZeo, Blast, HygroNEW

GrpEL spezifische siRNA, sHRNA Plasmide und shRNA Lentivirale Partikel Gen Silencer sind ebenfalls erhältlich.

BEZEICHNUNGKATALOG #REAKTIVITÄTANWENDUNGENMARKERReferenzen
GrpEL1 siRNA (h)
sc-89323HumanGene SilencingN/A
GrpEL1 shRNA Plasmid (h)
sc-89323-SHHumanGene SilencingPuromycin
GrpEL1 shRNA (h) Lentiviral Particles
sc-89323-VHumanGene SilencingPuromycin
GrpEL2 siRNA (h)
sc-91628HumanGene SilencingN/A
GrpEL2 shRNA Plasmid (h)
sc-91628-SHHumanGene SilencingPuromycin
GrpEL2 shRNA (h) Lentiviral Particles
sc-91628-VHumanGene SilencingPuromycin
GrpEL1 siRNA (m)
sc-145781MausGene SilencingN/A
GrpEL1 shRNA Plasmid (m)
sc-145781-SHMausGene SilencingPuromycin
GrpEL1 shRNA (m) Lentiviral Particles
sc-145781-VMausGene SilencingPuromycin
GrpEL2 siRNA (m)
sc-145782MausGene SilencingN/A
GrpEL2 shRNA Plasmid (m)
sc-145782-SHMausGene SilencingPuromycin
GrpEL2 shRNA (m) Lentiviral Particles
sc-145782-VMausGene SilencingPuromycin

GrpEL2 (GrpE protein homolog 2) is a 225 amino acid mitochondrial matrix protein and component of the PAM complex. Consisting of Tim44, Tim14, HSP 70, Magmas, GrpEL1 and GrpEL2, the PAM complex plays an essential role in the ATP-dependent translocation of transit peptide-containing proteins to the mitochondrial matrix from the inner membrane. GrpEL2 regulates the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins and stimulates its ATPase activity. The gene encoding GrpEL2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.