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Home »  Supportprodukte » Neurobiology-Specific Blockers and Activators
  Neurobiology-Specific Blockers and Activators
PRODUKT CATALOG # DESCRIPTION AMOUNT
sc-220850
Strong and selective inhibitor of kynurenine-3-hydroxylase.
5 mg
sc-200952
Shown to be a cytotoxic compound and a product of lipid peroxidation. Reported to cause neuronal and DNA damage via inhibition of NF-κB.
1 mg/10 mg
sc-221066
Mobilizes calcium in anterior pituitary cells.
50 µg
sc-204631
One of the six main active ingredients (a-pyrones) in kava-kava. Displays neuroprotective and antinociceptive activity.
5 mg/10 mg
sc-291924
Potent and selective NOP receptor antagonist (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). Inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro and antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant.
10 mg/50 mg
sc-362718
10 mg/50 mg
sc-221433
A cell permeable non-competitve inhibitor of γ-secretase.
250 µg/1 mg
sc-363785
1 g
sc-203030
Acts as a potent and competitive inhibitor of brain glucosyltransferase. Blocks the outgrowth of neurites.
50 mg
sc-221877
Non-peptide tachykinin antagonist that has high affinity for NK1 and NK2 receptors.
1 mg/5 mg
sc-204809
A bisbenzylisoquinolinium based muscle relaxant or neuromuscular blocker.
25 mg/100 mg
sc-215392
A potent, subtype selective mGluR5 antagonist.
10 mg
sc-221998
Melatonin receptor antagonist. More potent compared to Luzindole in the Xenopus melanophore assay.
1 mg/5 mg
sc-222059
A cell-permeable thiazole compound that acts as a potent and selective inducer of neuronal differentiation. Shown to induce the differentiation of adult neural progenitor HCN cells into mature neurons (10 µM for 10 days) and competitively suppress astrogliogenesis by LIF/BMP2/FBS in a dose-dependent manner. Reported to be non-cytotoxic and a more selective differentiation inducer than trans-retinoic acid.
5 mg
sc-222100
This is a metabolically stable and potent inhibitor of cellular anandamide uptake (neuronal (C6 glioma cells): IC50=2.6µM; non-neuronal (rat RBL-2H3 cells): IC50>20µM) with negligible effects on CB1 receptor (CB1: Kι=12.1µM; CB2: Kι>10µM), TRPV1 (EC50>10µM) and FAAH (IC50>100µM).
5 mg
sc-24016
Resiniferatoxin (RTX)-type phorboid vanilloid with capsaicin-like selectivity for VR1.
1 mg
sc-3580
A cationic amphiphillic molecule shown to block β1 and β2 adrenergic receptors, binds to 5-HT1B receptors, and inhibits phosphatidate phosphohydrolase.
1 g/5 g
sc-222237
Spirodecanone-site blocker.
1 mg/5 mg
sc-204892
An aminosteroid non-depolarizing neuromuscular blocker. Also used as a muscle relaxant used in modern anesthesia to facilitate endotracheal intubation.
10 mg/25 mg
sc-363290
This product is a neurotensin antagonist that displays selectivity for NTS1 over NTS2.
10 mg/50 mg
sc-362813
10 mg/50 mg
sc-222410
Selective inhibitor of anandamide uptake; non-neuronal: with negligible action at TRPV1 and weak action at CB1 receptor and FAAH.
1 mg
sc-362818
10 mg/50 mg
sc-301980
WS-12 is a high-affinity, selective TRPM8 (cold menthol receptor 1; CMR1) agonist. It has been found to induce a cooling sensation in sensory neurons and play a major role in physiopathology as a tumor marker with significant potential use in diagnosis and a target for cancer therapy.
5 mg
sc-296705
Xylamine is a selectively irreversible inhibitor of norepinephrine uptake into central and peripheral noradrenergic neurons.
10 mg