| PRODUKT |
CATALOG # |
DESCRIPTION |
AMOUNT |
|
sc-220850 |
Strong and selective inhibitor of kynurenine-3-hydroxylase. |
5 mg |
|
sc-200952 |
Shown to be a cytotoxic compound and a product of lipid peroxidation. Reported to cause neuronal and DNA damage via inhibition of NF-κB. |
1 mg/10 mg |
|
sc-221066 |
Mobilizes calcium in anterior pituitary cells. |
50 µg |
|
sc-204631 |
One of the six main active ingredients (a-pyrones) in kava-kava. Displays neuroprotective and antinociceptive activity. |
5 mg/10 mg |
|
sc-291924 |
Potent and selective NOP receptor antagonist (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). Inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro and antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant. |
10 mg/50 mg |
|
sc-362718 |
|
10 mg/50 mg |
|
sc-221433 |
A cell permeable non-competitve inhibitor of γ-secretase. |
250 µg/1 mg |
|
sc-363785 |
|
1 g |
|
sc-203030 |
Acts as a potent and competitive inhibitor of brain glucosyltransferase. Blocks the outgrowth of neurites. |
50 mg |
|
sc-221877 |
Non-peptide tachykinin antagonist that has high affinity for NK1 and NK2 receptors. |
1 mg/5 mg |
|
sc-204809 |
A bisbenzylisoquinolinium based muscle relaxant or neuromuscular blocker. |
25 mg/100 mg |
|
sc-215392 |
A potent, subtype selective mGluR5 antagonist. |
10 mg |
|
sc-221998 |
Melatonin receptor antagonist. More potent compared to Luzindole in the Xenopus melanophore assay. |
1 mg/5 mg |
|
sc-222059 |
A cell-permeable thiazole compound that acts as a potent and selective inducer of neuronal differentiation. Shown to induce the differentiation of adult neural progenitor HCN cells into mature neurons (10 µM for 10 days) and competitively suppress astrogliogenesis by LIF/BMP2/FBS in a dose-dependent manner. Reported to be non-cytotoxic and a more selective differentiation inducer than trans-retinoic acid. |
5 mg |
|
sc-222100 |
This is a metabolically stable and potent inhibitor of cellular anandamide uptake (neuronal (C6 glioma cells): IC50=2.6µM; non-neuronal (rat RBL-2H3 cells): IC50>20µM) with negligible effects on CB1 receptor (CB1: Kι=12.1µM; CB2: Kι>10µM), TRPV1 (EC50>10µM) and FAAH (IC50>100µM). |
5 mg |
|
sc-24016 |
Resiniferatoxin (RTX)-type phorboid vanilloid with capsaicin-like selectivity for VR1. |
1 mg |
|
sc-3580 |
A cationic amphiphillic molecule shown to block β1 and β2 adrenergic receptors, binds to 5-HT1B receptors, and inhibits phosphatidate phosphohydrolase. |
1 g/5 g |
|
sc-222237 |
Spirodecanone-site blocker. |
1 mg/5 mg |
|
sc-204892 |
An aminosteroid non-depolarizing neuromuscular blocker. Also used as a muscle relaxant used in modern anesthesia to facilitate endotracheal intubation. |
10 mg/25 mg |
|
sc-363290 |
This product is a neurotensin antagonist that displays selectivity for NTS1 over NTS2. |
10 mg/50 mg |
|
sc-362813 |
|
10 mg/50 mg |
|
sc-222410 |
Selective inhibitor of anandamide uptake; non-neuronal: with negligible action at TRPV1 and weak action at CB1 receptor and FAAH. |
1 mg |
|
sc-362818 |
|
10 mg/50 mg |
|
sc-301980 |
WS-12 is a high-affinity, selective TRPM8 (cold menthol receptor 1; CMR1) agonist. It has been found to induce a cooling sensation in sensory neurons and play a major role in physiopathology as a tumor marker with significant potential use in diagnosis and a target for cancer therapy.
|
5 mg |
|
sc-296705 |
Xylamine is a selectively irreversible inhibitor of norepinephrine uptake into central and peripheral noradrenergic neurons. |
10 mg |