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Home »  Supportprodukte » Antibiotics and Cell Selection Agents
  Antibiotics and Cell Selection Agents
PRODUKT CATALOG # DESCRIPTION AMOUNT
sc-255823
Selective inhibitor of α(1→2)-mannosidases.
1 mg/5 mg
sc-287209
25 g
sc-210036
The epi- derivative of antibiotic Tetracycline which can exhibit a 250-fold higher toxicity depending on the system under study.
5 mg
sc-221146
5 mg
sc-297975
A more potent analog of geldanamycin which inhibits cancer growth and promotes apoptosis in multiple cell lines. A more potent antitumor agent than 17-AAG.
1 mg
sc-202012
A member of the phorbol family of tumor promoters, that has been used to prepare tritiated Phorbol 12,13-dibutyrate ([3H]-PDBu).
1 mg/5 mg
sc-202035
Shown to be an anti-biotic, anti-fungal, anti-protozoal, and anti-bacterial agent. Reported to be cytotoxic in vitro but may be inactivated through esterase inactivation.
1 mg/5 mg
sc-202905
An antibiotic produced by Streptomyces chrysomallus. The antibiotic is composed of actinomycin IV, VI and VII. Studies report that Actinomycin C has the ability to intercalate DNA.
5 mg/25 mg
sc-205926
An antitumor antibiotic.
200 µg
sc-257071
An amphophilic antibiotic with antifungal activity that inhibits the biosynthesis of β-glucan by selective blockage of β-glucan synthetase.
1 mg
sc-202917
Antibacterial activities. Antineoplastic. Associated with smooth muscles contraction and Na+/K+-ATPase inhibition.
1 mg
sc-200094
A polypeptide natural product antibiotic. Forms multimeric membrane pores which permit non-specific ion efflux.
5 mg/25 mg
sc-278692
Aminoglycoside antibiotic derived from kanamycin A. Effective against Gram-negative and Gram-positive bacteria.
1 g
sc-202457
An aminoglycoside antibiotic that is active against gram- negative bacteria. It has similar activity to Gentamicin (sc-29066).
250 mg/1 g
sc-353009
5 g/25 g
sc-210811
A semi-synthetic antibiotic related to Penicillin. Antibacterial.
1 g
sc-202951
Ampicillin is a β-lactam antibiotic within the penicillin family. This broad spectrum antibiotic is effective against gram-positive, gram-negative bacteria and anaerobic bacteria. Widely used in cell culture as a selective agent.
5 g/100 g
sc-207289
A synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II. Antineoplastic.
1 mg
sc-202953
Antitumor antibiotic, closely related to the cytotrienins. Significantly potentiates the action of several clinical antitumor agents.
1 mg
sc-202954
Antitumor antibiotic, closely related to the cytotrienins. Displays potent anticancer activities.
1 mg
sc-3690
This solution containing penicillin, streptomycin, and amphotericin B is effective against the most common forms of cell culture contamination: bacteria, yeast, and fungi. Effective working concentration: 10 mL/L.
6 x 100 ml
sc-202061
Has been shown to have antiproliferative, antiangiogenic, and antiparasitic characteristics, all of which are reported to be due to the inhibition of histone.
1 mg/5 mg
sc-202066
Blocks MMP-9 expression by interrupting the activator protein AP-1 signal. Nuclear hormone receptor agonist.
500 µg
sc-280606
1 mg/5 mg
sc-202962
Antibiotic with nematicidal, insecticidal, antibacterial and antifungal activity.
1 mg/5 mg
sc-202472
An Aspergillus mold natural product antibiotic with nematicidal and antimicrobial activity.
1 mg/5 mg
sc-202474
Antibiotic. Inhibitor of vascular endothelial growth factor (VEGF).
1 mg
sc-202475
The most effective inhibitor against complex II from all the atpenins. Belongs to a class of antifungal antibiotics isolated from Penicillium sp.
250 µg/1 mg
sc-280608
Inhibits bacterial protein biosynthesis by interrupting the functional cycle of Elongation Factor-Tu (EF-Tu). Weakly acidic.
1 mg/2.5 mg
sc-319843
500 µg
sc-202072
Shown to be a potent and specific inhibitor of vacuolar (V-type) ATPase enzymes, displays antifungal characteristics. Possible antiosteoporotic agent.
1 mg
sc-202073
An inhibitor of V-ATPase proteins. Demonstrates antibacterial and antinematodal action. Indicated as a possible suppressor of bone resorption.
1 mg
sc-280609
A mycotoxin within the enniatin family produced by Fusarium sp. ; reported to affect mitochondria through depletion of the transmembrane potential, induction of swelling and decreasing of calcium retention capacity.
1 mg/5 mg
sc-202493
Semisynthetic water-soluble derivative of rebeccamycin. Antitumor antibiotic. Topoisomerase II inhibitor. DNA intercalating agent.
250 µg/1 mg
sc-202077
A member of the thiopeptide antibiotic family, which is described to contain sulfur and highly modified cyclic peptides. Isolated from Streptomyces and structurally related to sulfomycin I.
1 mg
sc-202078
An antibiotic reported to be isolated from fermented Streptomyces bernensis. In comparison to Berninamycin B and C, reports show that the pyridine ring of Berninamycin D has fewer dehydroalanine structures on the carboxyl carbon.
500 µg
sc-204636
A quinone antibiotic agent. Found to inhibit reverse transcrisptase from HIV-1 to a greater degree than it inhibits cellular DNA polymerase alpha.
1 mg/5 mg
sc-280620
A tripeptide antibiotic that is employed in the transformation experiments of many species of plants that make use of the bar gene for selection. It is more effective than glufosinate in corn. In wheat, bialaphos was the most reliable selection criteria used to identify bar transformed plants.
100 mg
sc-202082
An antibiotic that strongly inhibits aflatoxin production by specific fungi via reduction of expression of genes encoding aflatoxin biosynthesis enzymes.
1 mg
sc-204655
Antibiotic that belongs to a group of cytosine amino nucleosides. Inhibits protein synthesis in eukaryotes and prokaryotes.
100 mg/25 mg
sc-202532
A cephalosporin antibiotic that inhibits cell wall synthesis and is active against a wide spectrum of common pathogens, including gram-positive and gram-negative bacteria.
50 mg/250 mg
sc-353131
An antimicrobial agent; it is effective against postoperative complications in surgical treatment of pulmonary, tracheal and mediastinal tumors.
1 g/5 g
sc-202989
Cefotaxime Sodium Salt is a third generation Cephalosporin β-lactamase resistant antibiotic with efficacy in prohibition of gram-positive and gram-negative bacterial cell wall synthesis.
250 mg/1 g
sc-357308
100 mg
sc-257222
A third generation β lactam antibiotic and member of the cephems subgroub of antibiotics that inhibits PBP3, PBP1A and PBP1B.
100 mg/250 mg
sc-357311
5 g/25 g
sc-257223
A first generation cephem antibiotic with a wide range of antibacterial activity. The compound is active against gram-positive and gram-negative bacteria.
100 mg/250 mg
sc-202994
Shown to be an anti-proliferative agent that inhibits catalytic activities of topoisomerase II. Has also been reported to cause an inhibition in RNA synthesis and induce single-strand scission via free radical formation.
5 mg/25 mg
sc-202098
A spirotetronic acid macrolide antibiotic. Inhibits cholesterol biosynthesis by interrupting the mevalonate pathway. Inhibits the activity of pyruvate carboxylase isolated from different sources.
1 mg
sc-202995
A specific and potent calcium ionophore antibiotic that can block TNF-α secretion and inhibit binding of aminoacyl-tRNA to ribosomes.
1 g/5 g
sc-202099
Inhibitor of the catalytic activity of human topoisomerase II. Potent antibacterial, antifungal, antiviral and antitumor profile. Chrysomycins may act as photoactivated crosslinkers of DNA to histones.
250 µg/1 mg
sc-202100
Is less active than vinyl analog, Chrysomycin A. Potent antitumor agent and an inhibitor of the catalytic activity of human topoisomerase II. Chrysomycins may photoactively crosslink DNA to histones.
250 µg/1 mg
sc-207434
Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Also an antibacterial adjunct.
10 mg
sc-29064
Fluoroquinolone antibiotic effective against a broad spectrum of bacteria and mycoplasma; few known resistant strains. Effective at low concentrations (10µg/mL).
1 g/5 g
sc-202103
A natural and active isomer of the abscission accelerating plant hormone.
500 µg/1 mg
sc-280646
Tetramic acid antibiotic. SecA inhibitor. Antibacterial, antifungal and cytotoxic agent. Methyl analog of equisetin.
1 mg/5 mg
sc-205634
A 14-member ring macrolide antibiotic and 6-O-methyl derivative of erythromycin; reported bacteriostatic action against gram-positive and gram-negative bacteria, including anaerobes.
100 mg/250 mg
sc-202106
A synthetic derivative of lactahydrin that is a cell permeable, irreversible and specific inhibitor of the 20S proteasome. Also involved in the ubiquitin-proteasome degradation pathway.
100 µg/1 mg
sc-294096
5 g/25 g
sc-200099
An antibiotic with anti-inflammatory properties. The compound is a potent antibiotic against anaerobic and gram-postive bacteria.
20 mg/100 mg
sc-200097
An antibiotic which inhibits bacterial protein synthesis via interaction with the 50s ribosomal subunit. Active against gram-positive and anaerobic bacteria.
20 mg/100 mg
sc-204694
An antiprotozoal agent.
1 g/5 g
sc-205261
A semi-synthetic antibiotic that suppresses the growth of gram-positive bacteria such as Staphylococcus.
1 g/5 g
sc-319871
1 g/5 g
sc-202108
Antibiotic. Displays antibacterial and antitumor activity.
500 µg
sc-204696
Shown to be an extremely potent antibiotic that targets most gram-negative bacteria. Found to induce apoptosis through interaction with the cytoplasmic membrane.
500 mg
sc-203006
A potent vacuolar-type H+-ATPase inhibitor. Reports indicate that Concanamycins are 18-membered macrolide antibiotics that are active against yeast and fungi, and are effective at nanomolar concentrations.
100 µg/500 µg
sc-202113
Shown to be a fungal metabolite and a potent mycotoxin. Also has been reported to inhibit inducible nitric-oxide synthase-dependent NO production.
1 mg/5 mg
sc-3503
An immunosuppressant that inhibits calcineurin and T-cell dependent antibody production, among other immunological processes.
100 mg/500 mg
sc-203012
An immunosuppresive cyclic peptide antibiotic.
1 mg/5 mg
sc-294254
100 mg/250 mg
sc-202125
A calcium-dependent, lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms.
1 mg
sc-200102
A nucleoside analog antibiotic that acts as a GMPS inhibitor. Inhibition of GMP results in a decrease of GDP and GTP levels.
10 mg/50 mg
sc-234523
An antimicrobial and photoactive compound within the tetracycline class of antibiotics.
100 mg
sc-205648
A quinolone antimicrobial antibiotic. May reverse drug resistance in human neuroblastoma cells.
5 g/25 g
sc-202141
A hydrophobic cyclic ester originally produced by Streptomyces aureus that has been reported to inhibit T-cell proliferation induced by IL-2.
1 mg
sc-294372
An inhibitor of dipeptidyl aminopeptidase IV.
5 mg/25 mg
sc-280681
An anti-neoplastic antibiotic agent originally isolated from Streptomyces peucetius var. caesius that is thought to act through formation of a DNA complex resulting in the interference of DNA polymerization.
1 mg
sc-204734
An antimicrobial tetracycline that acts as an inhibitor of a wide range of matrix metalloproteinases. Has been reported to block collagen activity, and downregulate the expression and activity of MMP-8 and MMP-9.
1 g/5 g
sc-337691
10 g
sc-358661
Antitumor antibiotic. Inhibits cell cycle at the G(2)/M phase and induces apoptosis.
1 mg/5 mg
sc-202599
Angucyclinone antibiotic. Shows antibacterial and moderate cytotoxic activity.
1 mg/5 mg
sc-203039
An erythromycin derivative that is shown to be a motilin receptor agonist in the human gastic antrum in vitro. Also reported to contain orexigenic activity.
1 mg
sc-202150
An ionophore antibiotic that inhibits Pdr5p. Studies indicate that it has cytotoxic activity in vitro and no genotoxic activity.
1 mg
sc-202153
An N-methylserine-derived acyl tetramic acid produced by a number of Fusarium species with antibiotic and cytotoxic activity.
1 mg
sc-204742
A potent macrolide inhibitor of CYP3A4 with anti-inflamatory and proklinetic properties.
5 g
sc-204743
Used as a common antibiotic.
5 g/25 g
sc-207634
A macrolide, acid labile compound derived from Erythromcyin. Shown to increase IL-1 and IL-2 levels.
10 g
sc-203046
Prenylated 4-hydroxycoumarin. Antitubercular antibiotic with potent activity against Mycobacteria.
1 mg/5 mg
sc-221610
Potent, naturally occuring non-steroid estrogenic compound. Agonist for estrogen receptor (ER) α and agonist/antagonist for ERβ with higher binding affinity than tamoxifen or both ERs.
1 mg/5 mg
sc-204760
A phosphonic acid epoxide antibiotic. Inhibits cell wall synthesis through interference with UDP-N-acetylglucosamine enolpyruvyl transferase activity.
5 g/25 g
sc-211542
An antibiotic.
100 mg
sc-202160
Shown to inhibit the catalytic activity of Topo II in an uncompetitive manner and also inhibit PP1 and PP2A. Also reported to be an antibiotic.
50 µg
sc-202616
An inhibitor of dopamine β-hydroxylase, blocks conversion of dopamine to norepinephrine.
50 mg
sc-202164
An antibiotic which suppresses nitric oxide toxicity in pancreatic islet cells and also interferes with protein synthesis by inhibition of elongation factor G at the ribosomal level.
50 mg
sc-202618A
Antibiotic peptide. Interferes with bacterial cell wall biosynthesis.
5 mg
sc-29065
Shown to be an aminoglycoside antibiotic that causes a bypass of nonsense mutations during translation. Also inhibits incorporation of amino acids into protein and can destroy fibroblasts.
1 g/5 g/25 g
sc-202167
Thiopeptide antibiotic. Potent activator of the tipA gene, a bacterial transcription regulator involved in multidrug resistance. Geninthiocin displays a 10-fold selectivity for bacteria over mammalian cells lines.
500 µg
sc-207711
An antibiotic complex consists of three closely related components, gentamicins C1, C2, C1a, and also Gentamicin A, which differs from the other members of the complex but is similar to Kanamycin C. Antibacterial.
1 mg
sc-207713
A complex of antibiotics composed of Gentamicins C1, C2, C1a and Gentamicin A.
1 mg
sc-203334
Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasma concentrations. Its extended stability and slow development of bacterial resistance allow long-term virus and tissue culture studies.
1 g/5 g
sc-280731
Inhibitor of plasminogen activator inhibitor (PAI-1).
1 mg/5 mg
sc-202169
The minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces which displays potent antibacterial, antifungal, antiviral and antitumor activity.
500 µg
sc-203061
An effective antibiotic against gram-positive organisms that is a naturally occurring ion channel-forming pentadecapeptide.
1 mg/5 mg
sc-280769
An atpenin-related, specific inhibitor of complex II (succinate-ubiquinone oxidoreductase).
250 µg/1 mg
sc-3516
An irreversible and selective inhibitor of tyrosine kinases with antiparasite and antineoplastic properties, and has been observed to be effective to several oncogene products.
100 µg/1 mg
sc-29067
Used for selection and maintenance of cells transfected with the Escherichia coli hygromycin resistance gene (hyg or hph).
1 g (20 ml)
sc-202183
An antibiotic that acts against Staphylococci and Helicobacter pylori and inhibits bacterial tryptophanyl-tRNA synthetase.
1 mg
sc-300835
This product is a Ca2+ ionophore that has been shown to be more effective than A23187 as a mobile ion carrier for Ca2+ .
1 ml
sc-351855
A member of the leucomycin family of macrolide antibiotics produced by Streptomyces kitasatoensis. May overcome anticancer drug resistance by inhibiting the binding of vinblastine or cyclosporin A to P-glycoprotein (Pgp).
100 mg
sc-280874
5 g/10 g
sc-202680
An aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. It is highly potent against gram-negative bacteria.
250 mg
sc-263433
An aminoglycoside antibiotic which binds to 70S ribosomal subunit, inhibiting translocation and eliciting miscoding. Exhibits antimicrobial activity to Gram-negative and -positive bacteria and mycoplasm.
1 g/5 g
sc-257635
An aminoglycoside-antibiotic with broad antibacterial spectrum, (including mycobacteria, many gram-positive and most gram-negative organisms).
5 g
sc-29069
Aminoglycoside antibiotic effective against most gram negative, many gram-positive bacteria, and some Mycobacterium by interfering with protein synthesis. Often used as a marker for transgenic plants.
6 x 50 ml
sc-207777
An antibiotic which inhibits the growth of Saccharomyces cerevisiae and a variety of human pathogenic fungi, including Candida albicans.
10 mg
sc-200104
An aminoglycoside antibiotic that potently inhibits both gram-positive and gram-negative bacteria and blocks translation initiation.
1 g
sc-202194
A potent antibiotic with strong antifungal activity that is produced by actinomycete. Urological cancer cell research reports that it has the ability to induce G2 cell cycle arrest and delay the M phase.
100 µg
sc-202195
A minor component of the leptomycin complex that displays broad antitumor activity along with antibacterial and antifungal activity.
100 µg
sc-202196
A polyketide macrolide natural product. Demonstrates antibacterial activity against MRSA and VRSA bacteria, and cytotoxicity to certain tumor cell lines. Endothelin receptor antagonist and calcitonin receptor agonist.
100 µg/500 µg
sc-202197
A kigamicin antibiotic active against gram-positive and MRSA bacteria. Antiproliferative against nutrient-deprived PANC-1 pancreatic cancer cells through blockade of starvation-stimulated PKB/Akt activation.
500 µg
sc-257647
This compound exhibits antibacterial activity.
250 mg
sc-295334
A building block of peptide antibiotics and a valuable chiral synthon. Has been used for obtaining β-mercaptophenylalanine. Introduction of this Phe derivative allowed native chemical ligation at Phe followed by desulfuration.
1 g/5 g
sc-300898
This product is an antibiotic peptide found in milk and colostrum, and has been shown to protect from bacterial infection at mucosal surfaces.
1 mg
sc-202204
A pyranonaphthoquinone antibiotic. Demonstrates efficacy against gram-positive bacteria and neoplastic cells. Inhibits AKT serine/threonine kinase activity.
250 µg
sc-205731
A synthetic progestin that binds to progesterone and androgen receptors but not the estrogen receptor. Induces apoptosis in ovarian epithelium cells.
100 mg/500 mg
sc-200105
Lincomycin is a lincosamide antibiotic isolated from Streptomyces lincolnensis which is reported to inhibit bacterial protein synthesis and is concentration dependent. Inhibits bacterial protein synthesis via interaction with the 50s ribosomal subunit.
1 g/5 g
sc-200107
An antibiotic that targets bacteria, yeast and fungi. It can inhibit RNA synthesis during chain initiation and elongation, and chelates bivalent cations.
10 mg/50 mg
sc-202214
A member of the echinomycin (quinomycin A) class of antitumor and antibiotic agents that act by formation of a stable DNA complex by bis-intercalation. A potent inhibitor of HIV-1 reverse transcriptase.
1 mg
sc-202216
Belongs to a novel structural class with highly selective antibiotic activity. Lydicamycin and related metabolites, Antibiotic TPU-0037-A and Antibiotic TPU-0037-C, are highly active against MRSA.
500 µg
sc-204067
Ansamycin antibiotic compound that inhibits Hsp90 activity (IC50 = 2 μM) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC50 ~ 0.4 μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher potency and affinity than geldanamycin.
1 mg
sc-280949
A macrolide antibiotic and an inhibitor of cell-cell adhesion molecule.
1 mg/5 mg
sc-362766
Maduramicin is a polyether antibiotic first isolated from Actinomadura yunnaense (formerly Nocardia sp. X-14868) in 1963.
5 mg
sc-280953
Inhibitor of bleomycin-induced G2 arrest. Has antibacterial, antimalarial and antitrypanosomal activity. Induces root curvature and malformation in plants and enhances fibrinolytic activity in plants.
250 µg/1 mg
sc-205383
An antiprotozoal drug for leischmaniasis.
50 g/250 g
sc-203132
A low-molecular-mass protein with antibiotic properties.
1 mg
sc-205746
Shown to be a cell-permeable compound that inhibits bacterial growth via a high affinity for cell wall-synthesizing enzymes. Also reported to lack the toxic effects of similar compounds.
25 mg/100 mg
sc-215309
An initiator of folic acid metabolism and an inhibitor of dihydrofolate reductase (DHFR). Also available as Methotrexate (sc-3507).
100 mg/500 mg
sc-204805
A limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria.
5 g/25 g
sc-359617
An imidazole nucleoside immunosuppressant agent that was first isolated from the mold Eupenicillium brefeldimium with antibiotic and cytotoxic effects.
10 mg/25 mg
sc-205755
An imidazole nucleoside immunosuppressant agent that was first isolated from the mold Eupenicillium brefeldimium with antibiotic and cytotoxic effects.
10 mg/25 mg
sc-202230
A member of the macrotetrolide complex. Monactin inhibits T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and IFNγ.
1 mg
sc-228609
100 mg
sc-200971
Suppress the T-lymphocytic and antibody responses and shows antiproliferative properties without cytotoxic effects.
20 mg/100 mg
sc-200110
A small molecule inhibitor of IMPDH (inosine-5'-monophosphate dehydrogenase).
100 mg/500 mg
sc-279902
100 mg
sc-203154
A naphthalenic ansamycin antbiotic isolated from Streptomyces. Napthomycins are ansa macrocyclic antimetabolites that have been described in studies to show high cytotoxic activity against various leukemic cells.
1 mg
sc-202240
A macrocyclic antibiotic isolated from Streptomyces strains.
500 µg
sc-3573
Aminoglycoside antibiotic effective against most gram negative and gram positive bacteria; interferes with initiation, translation and elongation by binding to ribosomes; a phospholipid inhibitor.
1 g/5 g
sc-281103
An alkaloid and an antimitotic / antiproliferative agent. A member of a novel class of biologically active indole alkaloids characterized by a unique spiroaminal framework.
1 mg/5 mg
sc-204817
An active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria.
1 mg/5 mg
sc-203158
DNA minor groove binding ligand with potential antibiotic and antiviral properties
5 mg
sc-281104
A novel form of nerve growth factor (NGF) potentiator.
1 mg/5 mg
sc-205769
A nitrofuran antibiotic which inhibits the growth of Histomonas meleagridis but is not lethal to the flagellated protozoan.
25 g/100 g
sc-281105
A cyclic siderophore. Stimulates secondary metabolite formation and morphological differentiation in various actinomycete strains. Also induces morphological changes in insect cells.
1 mg/5 mg
sc-203164
A cyclic ionophore and part of the macrotetrolide antibiotics family. The ionophore is commonly produced by several species of Streptomyces which selectively binds K+ and NH4+. Contains many biological and bioassay functions.
5 mg/25 mg
sc-202262
An antibiotic that acts as a nonselective inhibitor of ATP synthase, produced by Streptomyces sp.
5 mg
sc-202263
An ATP synthetase inhibitor that belongs to a class of macrolide antibiotics and is a potent inhibitor of cell regulatory volume decrease (RVD).
1 mg
sc-205779
Anti-infective; used to to treat selected protozoan infections.
5 g/50 g
sc-202269
A macrolide antibiotic that reversibly inhibits translation at the bacterial 50S ribosome. When combined with Virginiamycin S1, the two produce a bacteriocidal effect.
5 mg
sc-205781
A member of the penicillin class of antibiotics.
1 g/5 g
sc-224180
1 g/5 g
sc-205784
An anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis. Shown to be an inhibitor of NF-κB activation via phosphorylation and degradation of IκBα.
10 g/50 g
sc-204832
A aminoglycoside antibiotic.
1 g/5 g
sc-205796
A mutagenic and cytotoxic mycotoxin. Induces single-strand DNA breaks. Irreversibly inactivates GDP-mannose dehydrogenase.
5 mg/10 mg
sc-344973
A β-lactam antibiotic produced by Penicillium spp.; effectiveness mainly against gram-positive organisms with activity against some gram-negative organisms.
100 mg
sc-205797
A β-lactam antibiotic produced by Penicillium chrysogenum combined with sodium channel blocker Procaine.
10 g/25 g
sc-257971
Penicillin G sodium salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium sp.. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Some gram-negative organisms such as Neiserria gonorrhoeae and Neiserria meningitidis are also reported to be susceptible to Penicillin G. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose into penillic acid and penilloic acid. Penicillin G is also available alone (sc-344973) and in salt form as Penicillin G potassium (sc-255411).
1 mg/10 mg/1 g/5 g/100 g
sc-202278
A pyran-2-one metabolite that can act as a gibberellin synergist.
500 µg
sc-204840
A heptapeptide phallotoxin isolated from Amanita phalloides. Stabilizes filamentous F-actin, interfering with normal cell functioning and inducing cell death.
1 mg
sc-205964
A biotinylated Phalloidin (sc-202763) derivative that is able to bind both actin and avidin/streptavidin simultaneously due to the long spacer inserted between the two active components.
100 µg
sc-204845
A metal-complexing antibiotic related to Bleomycin. Forms a Cu(II) complex which induces oxidative degradation of DNA.
5 mg/25 mg
sc-202287
An antibiotic and a member of the Class I inhibitors that acts as an effective inhibitor of the bacterial and mitochondrial type I NADH-ubiquinone oxidoreductases (Complex I).
2 mg
sc-202291
Shown to be a more potent analogue of Platensimycin. Reported to target two essential proteins: FabF and FabH.
100 µg
sc-202292
Broad spectrum gram-positive antibiotic. Believed to inhibit bacterial growth by selectively inhibiting elongation enzyme, β-ketoacyl acyl carrier protein synthase FabF of the fatty acid synthesis pathway.
250 µg
sc-202293
A potent diterpene antibiotic with activity against gram-positive bacteria and inhibits peptide bond formation.
25 mg
sc-202294
Tetracyclic quinone glycoside. Displays antibacterial, antimalarial and antitumor activity.
1 mg
sc-202299
An antibiotic isolated from Pseudomonas fluorescens. Inhibits protein and RNA synthesis through inhibition of isoleucyl-tRNA synthetase. Active against multiply resistant staphylococci and streptococci.
25 mg
sc-202300
A heterospirocyclic antibiotic. Inhibits chitin synthase. Stimulates differentiation of PC12 neuronal cells. Suppresses IgE production.
1 mg
sc-202778
Nucleoside antibiotic. Antitumor compound. Inhibitor of xanthosine monophosphate (XMP) aminase. Antimetabolite within the purine biosynthesis.
1 mg/5 mg
sc-205965
Used as photochemical probe in studies of DNA mutation and repair mechanisms. Causes photosensitization in human.
25 mg/100 mg
sc-205821
Puromycin is an aminonuclease antibiotic produced by the soil actinomycete Streptomyces alboniger which induces apoptosis in cells by interfering with RNA function. Toxic to both eukaryotic and prokaryotic cells.
10 mg/25 mg
sc-200112
A puromycin analog which does not inhibit protein synthesis or induce apoptosis. It is a glomerular epithelial cell toxin which may be used to induce nephropathy in laboratory animals.
50 mg/250 mg
sc-108071
Aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene (S. alboniger), whose product, puromycin-N-acetyl-transferase, inactivates puromycin via acetylation.
25 mg/50 mg/250 mg
sc-281140
Has phytotoxic and antihelmintic activity. Also a prolyl endopeptidase inhibitor.
1 mg/5 mg
sc-205828
A common antimalarial agent that has been found to enhance the antitumor activity of doxorubicin against multidrug-resistant cancers K562/A02 and MCF-7/ADR.
100 mg/250 mg
sc-205966
Shows weak cytotoxic activity against different tumor cell lines. And has antiparasitic activity.
1 mg/5 mg
sc-202304
A cyclic peptide antibiotic bearing two naphtyl intercalating moieties. Produces bis-intercalation of DNA strands, generating antimicrobial and cytotoxic effects.
500 µg
sc-253424
A potent cyclic lipoglycodepsipeptide antibiotic, that has been reported to be active against aerobic and anaerobic gram-positive bacteria.
250 mg
sc-204876
Cytotoxic secondary metabolite that inhibits cell growth of mammalian cell lines in the picomolar range (IC50=0.2ng/ml with L929 mouse cells) including multidrug resistant (MDR) HeLa cells (IC50=0.1ng/ml with KB-V1).
5 µg
sc-202309
An indolocarbazole antibiotic. Intercalates with DNA and inhibits topoisomerase I.
250 µg/1 mg
sc-203235
Antibiotic. Shows antibacterial, antifungal, antiviral and antitumor activity.
1 mg/5 mg
sc-202311
Rare, boat-shaped, pentacyclic polyketide often co-produced with resistomycin. Has weak antibacterial activity. Potent cytotoxic activity against tumor cell lines in vitro.
1 mg
sc-358699
Demonstrated antibacterial activity against Gram-positive and mycobacteria, and shown to Inhibit RNA polymerase; induces apoptosis.
1 mg
sc-202313
Isocoumarin metabolite. Potent inhibitor of cyclic nucleotide phosphodiesterase. Inactivates topoisomerase I and causes a dose dependent inhibition of lung metastasis in B16F10 melanoma model.
250 µg/1 mg
sc-202315
Much less active analogue of reveromycin A formed by rearrangement of the 6:6 spiroketal to a 5:6 spiroketal. Reveromycin B is a useful negative control in resolving the mode of action of this class.
250 µg
sc-202316
A member of the Reveromycin antibiotic family isolated from Streptomyces culture broth. Demonstrates inhibition of mitogenic activity in response to EGF signaling.
250 µg
sc-202317
Isopentyl reveromycin analogue. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C.
250 µg
sc-212784
A Rifamicyn derivative with therapeutic effect on pulmonary tuberculosis.
10 mg
sc-205841
An antibiotic that inhibits RNA synthesis in bacteria and acts as a PXR activator. Has been shown to act strongly against Enterococcus, Streptococcus and Staphylococcus, with less activity against Enterobacteriaceae.
500 mg/1 g
sc-202318
An antibiotic that belongs to the class III glycopeptides. Has activity against gram-positive and gram-negative bacteria, and can be used in chromatography.
10 mg
sc-205970
Antibacterial and antitumor compound.
1 mg/5 mg
sc-203258
A bromopyrrole alkaloid natural product, inhibits cell contractility and motility.
1 mg
sc-203263
Sinefungin is a DNA methyltransferase inhibitor and an analog of s-adenosyl-L-methionine (SAM, AdoMet) and may have antiviral, antiparasitic, anticancer and antifungal properties.
1 mg
sc-202339
Shown to be an antibiotic thiazole compound that down-regulates FoxM1 and it’s downstream target genes. Also reported to induce potent p53-independent apoptosis in cancer cell lines of different origin.
500 µg
sc-208390
A Gentamicin-like aminoglycoside antibiotic that exhibits broad spectrum antibiotic activity.
1 g
sc-203279
Spectinomycin is an aminocylcitol antibiotic which is closely related to the aminoglycosides. Active against gram-positive and gram-negative Gonococcus spp.
5 g
sc-286778
1 g/5 g
sc-200114
Spectinomycin is an aminoglycoside antibiotic and a suppresor of protein synthesis in susceptible prokaryotes.
10 g
sc-215899
An antibiotic isolated from Bacillus laterosporus that has antibacterial, antitumor and strong immunosuppressive properties.
1 mg
sc-202821
An aminocyclitol glycoside antibiotic which interfers with protein synthesis in prokaryotes. Effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media.
10 g/100 g
sc-203284
A broad spectrum antibacterial compound with antiviral activity, that contains a streptolidine ring, a glucosamine, and a polylysine side chain. Candida albicans studies indicate that C. albicans is susceptible to Streptothricin sulfate.
1 mg/5 mg
sc-264327
Antibiotic (sulfonamide class) that blocks dihydrofolic acid synthesis via inhibition of the dihydropteroate synthase enzyme in prokaryotes. Antibacterial activity has been recognized in Gram positive, Gram negative, and Chlamydia.
100 g
sc-229345
A sulfonamide antibacterial agent.
50 mg
sc-202349
A fungal metabolite isolated from both Penicillium sp. and Asperigillus, described to inhibit the degranulation, activation and chemotaxis of eosinophils.
1 mg
sc-202827
Antibiotic with broad activity, as well demonstrated antitumor, antiangiogenic, and antiendotoxin activity; also found to induce apoptosis in tumor cell models.
10 mg/50 mg
sc-208419
Glycopeptide antibiotic produced by Actinoplanes teichomyceticus; efficacy against gram-positive cocci via inhibition of cell wall synthesis.
50 mg
sc-202355
Teicoplanin Complex is a complex of antibiotics produced by Acintoplanes teichomyceticus; reported to be effective against gram-positive cocci.
25 mg/50 mg
sc-202356
A 3-hydroxyproline-containing peptide antibiotic that potently inhibits gram-postive bacteria, with little or no effect on gram-negative bacteria.
500 µg
sc-202357
Antineoplastic compound exhibiting antitumor, antiviral and antibacterial activity. Inhibits protein synthesis by suppression at the ribosome. May act as a mycotoxin.
500 µg
sc-286815
1 mg/2 mg
sc-29070
An antiobiotic that inhibits protein synthesis in bacteria by blocking the binding of aminoacyl-tRNA to the bacterial ribosome and has been used in a variety of root canal studies.
5 g
sc-229400
A broad spectrum antibiotic produced by Streptomyces aureofaciens that is useful in an array of bioassays.
25 g
sc-202359
A tetronic acid that has been shown to be active against antibiotic resistant and susceptible gram-positive bacteria including MRSA.
500 µg
sc-202360
An unusual tetronic acid structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Targets the PI 3-Kinase/Akt signalling pathway.
500 µg
sc-358574
100 g/500 mg
sc-203412
A cyclic peptide antibiotic. Blocks dissociation of EF-G from the ribosome, preventing turnover and impeding protein synthesis.
1 g/5 g
sc-281171
Mixed in ratio of 15:1 Ticarcillin is an inhibitor of bacterial cell wall synthesis. It inhibits the crosslinking of peptidoglycan by binding and inactivating of transpeptidases. High activity against gram-(-) bacteria and this combination is effective against resistant Agrobacterium strains.
2 g/10 g
sc-204917
Free base. Aminoglycoside antibiotic with similar structure to the kanamycins and gentamycins. Used in the treatment of respiratory infection and cystic fibrosis.
10 mg/50 mg
sc-362812
Toyocamycin is a pyrrolopyrimidine nucleoside isolated from Streptomyces toyocaensis in 1956. Toyocamycin, like other members of pyrrolopyrimidine class, is an adenosine nucleotide antimetabolite with a broad spectrum of action against bacteria, fungi, protozoans and mammalian cell lines.
1 mg
sc-202369
A fungistatic antibiotic isolated from Streptomyces sp. Less potent than its analog Trichostatin A, acts as an effective inducer of erythroid differentiation in a murine erythroleukemia cell line. Reported to increase histone H4 acetylation level in vitro.
500 µg
sc-202370
A hydrophobic cyclic ester that acts as a macrotetrolide antibiotic, isolated from Streptomyces aureus.
1 mg
sc-258322
Toxic adenosine analog with antiviral, antitrypanosomal, and antifungal functions. Inhibits multiple metabolic processes which includes: RNA processing, nucleic acid synthesis, protein synthesis, and methylation of tRNA through intracellular incorporation into nucleic acids. Acts as a plant antifungal, inhibits mammalian SAH hydrolase (SAHH), and blocks purine biosynthesis in Candida famata.
10 mg/50 mg
sc-204932
A macrolide antibiotic Isolated from Streptomycetes fradiae shown to reduce the percentage of the general mucolytic bacteria and the concentration of C. perfringes and to have activity against sensitive Mycoplasma.
1 g/5 g
sc-204933
A macrolide antibiotic which affects sensitive mycoplasma organisms. Shown to enhance the chicken immune system.
1 g/5 g
sc-281183
Inhibits Trehalase activity. Enhances the accumulation of trehalose in transgenic plants.
1 g
sc-204938
Glycopeptide antibiotic that interferes with cell wall synthesis. Effective against Gram-positive bacteria.
250 mg/1 g
sc-202380
An antibiotic that inhibits E. coli H+-ATPase by acting on membrane sector F0 which causes voltage sensitive K+ channels.
1 mg
sc-202381
An antibiotic that has been reported to be a potent inhibitor of mitochondrial ATP synthase complex. Also shown to interfere with proton channels.
250 µg
sc-202383
A solid mixture of 75% virginiamycin M1, 25% virginiamycin S1 streptogramin antibiotics. Synergistic activity is developed by the two, producing a bacteriocidal effect when combined.
5 mg
sc-202384
A streptogramin antibiotic presenting bacteriocidal effects when combined with virginiamycin M1. S1 and M1 operate synergistically and irreversibly inhibit protein synthesis.
5 mg
sc-202385
A 3-hydroxy-4-arylquinolin-2(1H)-one fungal metabolite isolated from Penicillium species. Efficacious against Mycobacterium tuberculosis.
1 mg
sc-358715
Inhibits virulence regulation in V. cholerae. Prevents expression of cholera toxin and the toxin coregulated pilus (TCP) by inhibiting the transcriptional regulator ToxT. Effectively protects infant mice against TCP-dependent V. cholerae intestinal colonization in vivo. Displays little toxicity towards mammalian cells (up to 2mM for Hep2 cells).
10 mg/50 mg
sc-281184
A 18-membered macrolide. Active against trichomonads and various RNA and DNA viruses.
1 mg/5 mg
sc-301978
This product is a fluorescent bisintercalating anthracycline antibiotic. It has been shown to inhibit basal transcription by RNA polymerase II.
200 µg