epitope mapping near the N-terminus of FAM109B of human origin
recommended for detection of FAM109B of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
FAM109B Background Information Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. The FAM109B gene product has been provisionally designated FAM109B pending further characterization.
FAM109B (N-17)
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FAM109B (N-17): sc-86440. Western blot analysis of FAM109B expression in mouse heart tissue extract.