epitope corresponding to amino acids 28-135 mapping near the N-terminus of ALCAM of human origin
recommended for detection ALCAM of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
ALCAM Background Information Activated leukocyte cell adhesion molecule (ALCAM), expressed on activated leukocytes T cells, B cells and monocytes, is a member of the immunoglobulin superfamily (IgSF) and identified as a CD6 ligand. CD6 is a type I membrane protein in the scavenger receptor cysteine rich protein superfamily that acts in T cell adhesion and costimulation. ALCAM mediates thymocyte-thymic epithelial cell adhesion via homophilic (ALCAM-ALCAM) and heterophilic (ALCAM-CD6) interactions involving a previously undescribed protein-protein interaction between a member of the scavenger receptor cysteine rich protein superfamily and the immunoglobulin superfamily.
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ALCAM (H-108)
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ALCAM (H-108): sc-25624. Western blot analysis of ALCAM expression in Daudi whole cell lysate.
ALCAM (H-108): sc-25624. Immunofluorescence staining of normal mouse heart frozen section showing membrane and cytoplasmic staining.
