Opener of the cloned large-conductance, Ca2+-activated potassium (maxi-K) channel. Neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke).
Ausschließlich für Forschungszwecke (in-vitro, laboratory research use only)
Literaturhinweise
1. Hewawasam, P., et al. 2003. Bioorg. Med. Chem. Lett. 13: 1695-1698.
2. Romine, J.L., et al. 2007. J. Med. Chem. 50: 528-542.