TRAM-34 has been shown to be an inhibitor of cloned and native IK1 channels in human T lymphocytes. These K+ channels have been implicated in over-proliferation of cells. Inhibition of IK1 channels has been demonstrated to modulate cell proliferation depending on the concentration of TRAM-34. Mechanistic studies have shown that TRAM-34 may cause a halt in cell growth at the G0/G1 phase.
LAGERUNG:
Store as supplied, at room temperature for up to 1 year. Store solutions at -20° C for up to 3 months.
Ausschließlich für Forschungszwecke (in-vitro, laboratory research use only)
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
