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- Technische Daten
- Im Angebot als 100 mg (sc-200992) und 500 mg (sc-200992A) sizes
- CAS Nummer: 624-00-0
- Molekulargewicht: 210.3
- Summenformel: C10H19O3 ·Na
- Reinheit: 98%
- Produktform: Solid
- Physisches Aussehen: White solid
- Löslichkeit: Soluble in water (25 mg/mL)
- SMILES: CCCCCC(CCCC(=O)[O-])O.[Na+]
- Beschreibung
- 5-Hydroxydecanoate Na (5-HD) is a substrate for mitochondrial outer membrane acyl-CoA synthetase that inhibits ATP-sensitive K+ channels. In neuronal type K sensitive ATP channel currents, 5-Hydroxydecanoate Na diminished the produced activation of the channels by PKG. On perfused rat hearts, 5-Hydroxydecanoate Na has shown the ability to inhibit the toxicity of 6-hyrdoxydopamine on dopaminergic neurons. 5-Hydroxydecanoate Na has displayed a lack of activity in inhibiting oxygen consuming mitochondria derived from skeletal muscle.
- LAGERUNG:
- Ausschließlich für Forschungszwecke (in-vitro, laboratory research use only)
- The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
- Weitere Referenznummern
- PubChem Compound ID: 23676659
- MDL Nummer: MFCD00153808
- Literaturhinweise
- 1. Notsu, T., et al. 1992. J. Pharmacol. Exp. Ther. 260: 702-708. PMID: 1738118
2. Rodriguez-Pallares, J., et al. 2009. Neurotox Res. 15: 82-95. PMID: 19384591
3. Chai, Y., et al. 2010. Am. J. Physiol., Cell Physiol. 298: C875-C892. PMID: 20053925
4. Li, X., et al. 2010. Biochim. Biophys. Acta. 1800: 385-391. PMID: 19931596
5. Montoya-Pérez, R., et al. 2010. J. Bioenerg. Biomembr. 42: 21-27. PMID: 20066482
6. Botha, P., et al. 2010. Transplantation. 89: 169-177. PMID: 20098279
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5-Hydroxydecanoate Na
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