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PCO 400: sc-200989

 |  Datenblatt  | MSDS
  • Technische Daten
    • Im Angebot als 20 mg (sc-200989) und 100 mg (sc-200989A) sizes
    • CAS Nummer: 121055-10-5
    • Molekulargewicht: 299.3
    • Summenformel: C17H17NO4
    • Physisches Aussehen: White solid
    • Löslichkeit: Soluble in ethanol (30 mg/mL) and DMSO (>200 mg/mL)
    • SMILES: CC1(C(C(C2=C(O1)C=CC(=C2)C#N)OC3=CC(=O)CC3)O)C
  • Beschreibung
    • This product is an analog of comakalim and a selective and potent ATP-sensitive K+ channel opener. It has been shown to evoke relaxation of isolated airway smooth muscle in a dose-dependent manner. Upon intravenous injection, transient inhibition of histamine-induced bronchospasm was effected. Inhaled as a dry powder, it can suppress the development of allergic airway hyperreactivity to histamine.
  • LAGERUNG:
    • Store as supplied at room temperature for up to 1 year. Store solutions at - 20° C for up to 3 months.
  • Ausschließlich für Forschungszwecke (in-vitro, laboratory research use only)
    • The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
  • Weitere Referenznummern
  • Literaturhinweise
    • 1. Robertson, D.W., et al. 1990. J. Med. Chem. 33: 1529-1541. PMID: 2187993
      2. Edwards, G., et al. 1990. Trends Pharmacol. Sci. 11: 417-422. PMID: 2256183
      3. Chapman, I.D., et al. 1992. Br. J. Pharmacol. 106: 423-429. PMID: 1382782
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 Bestellinformationen
ProduktKatalog #MengePreisAnzahlKaufFavorit
PCO 400 sc-200989 20 mg $50
PCO 400 sc-200989A 100 mg $203
PCO 400
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PCO 400
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