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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within an internal region of GASP-2 of human origin
- recommended for detection of GASP-2 of human origin and GASP2 of mouse origin by WB, IP, IF and ELISA; non cross-reactive with GASP-1
- blocking peptide, sc-162842 P
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GASP-2 Background Information
G protein-coupled receptors play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GASP-2 (G protein-coupled receptor associated sorting protein 2), also known as GPRASP2, is an 838 amino acid protein that regulates a number of G-protein coupled receptors, such as CT-R (calcitonin receptor) and mAChR M1 (muscarinic acetylcholine receptor M1), through interactions with their cytoplasmic tails. Expressed primarily in brain, GASP-2 is a member of the GPRASP family and forms a complex with Huntingtin, with which it is thought to influence receptor trafficking. |
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GASP-2 (E-14)
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GASP-2 (E-14): sc-162842. Western blot analysis of GASP-2 expression in non-transfected: sc-117752 (A) and human GASP-2 transfected: sc-111294 (B) 293T whole cell lysates. |
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