Toxins

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, free base
A dopaminergic neurotoxin which reportedly causes a severe and irreversible Parkinsonian condition in humans and monkeys.
Katalog # CAS Nummer Summenformel Menge
sc-208657 28289-54-5 C₁₂H₁₅N 25 mg
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Hydrochloride
A dopaminergic neurotoxin that causes a severe and irreversible Parkinsonian condition in humans and monkeys.
Katalog # CAS Nummer Summenformel Menge
sc-206178 23007-85-4 C₁₂H₁₆ClN 25 mg
Aaptamine
Aaptamine is a spongean alkaloid that can activate the p21 promoter in the absence of p53 and can function as a proteasome inhibitor.
Katalog # CAS Nummer Summenformel Menge
sc-202899 85547-22-4 C₁₃H₁₂N₂O₂ 1 mg
Aconitine
A lipid-soluble and potent neurotoxin that activates voltage gated sodium channels.
Katalog # CAS Nummer Summenformel Menge
sc-202441 302-27-2 C₃₄H₄₇NO₁₁ 25 mg
α-BUNGAROTOXIN
Acetylcholine receptor (AChR) blocker which blocks neuromuscular transmission via irreversible binding to the acetylcholine receptor to the motor end-plate.
Katalog # CAS Nummer Summenformel Menge
sc-202897 11032-79-4 C₃₃₈H₅₂₉N₉₇O₁₀₅S₁₁ 1 mg
α-Sarcin, Aspergillus giganteus
Native α-sarcin from Aspergillus giganteus. α-Sarcin is a ribosome-inactivating protein that has been demonstrated to induce apoptosis in rhabdomyosarcoma cells. Suitable for induction of apoptosis and inhibition of protein synthesis.
Katalog # CAS Nummer Summenformel Menge
sc-204427 86243-64-3 n.n. 1 mg
α-Zearalenol
A synthetic derivative of the mycotoxin Zearalenone. Produces estrogenic effects three times more potently than the parent compound.
Katalog # CAS Nummer Summenformel Menge
sc-202388 36455-72-8 C₁₈H₂₄O₅ 5 mg
Alternariol
A mycotoxin that has been shown to inhibit the short action current across transepithelial sodium pumps. Also demonstrates the ability to have acute cytotoxic effects on cells.
Katalog # CAS Nummer Summenformel Menge
sc-202923 641-38-3 C₁₄H₁₀O₅ 1 mg
Azaspiracid-1
Activator of JNK. Cellular growth inhibitor and inducer of cytoskeletal alterations. Activator of caspases. Modulator of intracellular cAMP and calcium levels. Potent teratogen to finfish.
Katalog # CAS Nummer Summenformel Menge
sc-202482 214899-21-5 C₄₇H₇₁NO₁₂ 1 µg
Azaspiracid-2
Modulator of intracellular cAMP (cyclic adenosine monophosphate) and calcium levels.
Katalog # CAS Nummer Summenformel Menge
sc-202483 265996-92-7 C₄₈H₇₃NO₁₂ 1 µg
Azaspiracid-3
Modulator of intracellular cAMP (cyclic adenosine monophosphate), calcium and pH levels.
Katalog # CAS Nummer Summenformel Menge
sc-202484 265996-93-8 C₄₆H₆₉NO₁₂ 1 µg
β-Bungarotoxin
A snake venom neuro toxin with phospholipase A₂ activity shown to inhibit Acetylcholine release presynaptically at neuromuscular junctions and specificity for the cholinergic nerve terminals at the CNS.
Katalog # CAS Nummer Summenformel Menge
sc-202981 12778-32-4 n.n. 1 mg
Cobratoxin Purified
Katalog # CAS Nummer Summenformel Menge
sc-361980 12584-83-7 n.n. 10 mg
Citreoviridin
A mycotoxin that was initially isolated from Penicillium citreoviride. Has been found to potently inhibit mitochondrial ATPases via uncompetitive inhibition of ATP hydrolysis.
Katalog # CAS Nummer Summenformel Menge
sc-202545 25425-12-1 C₂₃H₃₀O₆ 1 mg/5 mg
Convulxin
Heterodimeric C-type lectin. Activates mammalian platelets via binding and clustering of p62/GPVI-receptors under physiological conditions.
Katalog # CAS Nummer Summenformel Menge
sc-202554 37206-04-5 n.n. 50 µg
Cylindrospermopsin
A cyanotoxin natural product. Inhibits protein synthesis. Decreases cellular GSH levels. Toxicity produced by cytochrome p450-generated metabolites.
Katalog # CAS Nummer Summenformel Menge
sc-203014 143545-90-8 C₁₅H₂₁N₅O₇S 25 µg/100 µg
Deepoxy-deoxynivalenol solution
Katalog # CAS Nummer Summenformel Menge
sc-234521 88054-24-4 C₁₅H₂₀O₅ 2 ml
Deoxynivalenol
A mycotoxin usually produced by Fusarium species. Shown to be an immunosuppressant at high concentrations and an immunostimulant at low concentrations.
Katalog # CAS Nummer Summenformel Menge
sc-204711 51481-10-8 C₁₅H₂₀O₆ 1 mg/5 mg
Diphtheria Toxin, CRM Mutant
A compound that does not have NAD:EF2 ADP-ribosyltransferase activity due to an amino acid substitution of glycine to glutamic acid.
Katalog # CAS Nummer Summenformel Menge
sc-203924 92092-36-9 n.n. 1 mg
Diphtheria Toxin from Corynebacterium diphtheriae
An exotoxin which inactivates polypeptide chain EF-2 (Elongation Factor 2). It is thought that cytolysis is a result of the toxin’s induction of extensive internucleosomal degradation of cellular DNA.
Katalog # CAS Nummer Summenformel Menge
sc-221549 92092-36-9 n.n. 500 µg/1 mg
Exotoxin A, Pseudomonas aeruginosa
A bacterial toxin originally derived from Pseudomonas aeruginosa that has been shown to arrest protein synthesis and cause apoptosis.
Katalog # CAS Nummer Summenformel Menge
sc-203949 91262-95-2 n.n. 1 mg
F16
Cell-permeable, fluorogenic, delocalized lipophilic cationic compound. Mitochondrial toxin with the dual ability to induce apoptosis as well as necrosis in tumor cells.
Katalog # CAS Nummer Summenformel Menge
sc-202604 36098-33-6 C₁₆H₁₅IN₂ 25 mg
Fusarenon X
Katalog # CAS Nummer Summenformel Menge
sc-235234 23255-69-8 C₁₇H₂₂O₈ 5 mg
Fumigaclavine A
Ergot alkaloid. Mycotoxin.
Katalog # CAS Nummer Summenformel Menge
sc-203051 6879-59-0 C₁₈H₂₂N₂O₂ 1 mg/5 mg
Gonyautoxin 2/3 Epimers
Neurotoxin. Epimeric mixture of gonyautoxin 2 and gonyautoxin 3, equally potent and selective Na⁺ channel blockers.
Katalog # CAS Nummer Summenformel Menge
sc-203433 60508-89-6 (GTXII); 60537-65-7 (GTXIII) C₁₀H₁₇N₇O₈S 1 Vial
Latrunculin A, Latrunculia magnifica
A macrolide marine toxin, binds and stabilizes G-actin, inhibiting polymerization into F-actin microfilaments.
Katalog # CAS Nummer Summenformel Menge
sc-202691 76343-93-6 C₂₂H₃₁NO₅S 100 µg
Latrunculin B, Latrunculia magnifica
Latrunculin B is a structurally unique marine toxin that Inhibits actin polymerization and disrupts microfilament organization and processes.
Katalog # CAS Nummer Summenformel Menge
sc-203318 76343-94-7 C₂₀H₂₉NO₅S 1 mg
Moniliformin
Katalog # CAS Nummer Summenformel Menge
sc-359847 31876-38-7 C₄H₂O₃ 1 mg
Moniliformin sodium salt
Mycotoxin
Katalog # CAS Nummer Summenformel Menge
sc-203140 71376-34-6 C₄HO₃ ·Na 1 mg/5 mg
Nonivamide
An agonist of the TRPV1 receptor, structurally related to Capscaicin. Stimulates afferent neurons with about half the potency of Capscaicin.
Katalog # CAS Nummer Summenformel Menge
sc-202735 2444-46-4 C₁₇H₂₇NO₃ 25 mg/100 mg
Ochratoxin A
A mycotoxin with nephrotoxic and teratogenic effects. Inhibits phenylalanyl-tRNA synthetases and phenylalanine-recognizing enzymes. Oxidative damage is identified as a partial mediator of toxic effects. Demonstrated to increase ATP-dependent Ca²⁺ pump activity in renal cortex endoplasmic reticulum.
Katalog # CAS Nummer Summenformel Menge
sc-202749 303-47-9 C₂₀H₁₈ClNO₆ 1 mg/5 mg
Ochratoxin B
The non-chlorinated much less potent and active analogue of Ochratoxin A (sc-202749).
Katalog # CAS Nummer Summenformel Menge
sc-202258 4825-86-9 C₂₀H₁₉NO₆ 1 mg
Paraherquamide A
Mycotoxin related to the indole tremorgenic mycotoxins. Selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.
Katalog # CAS Nummer Summenformel Menge
sc-202275 77392-58-6 C₂₈H₃₅N₃O₅ 1 mg
Pectenotoxin-2
Potent disruptor of actin cytoskeleton in living cells. Forms 1:1 complexes with monomeric actin and caps actin filaments.
Katalog # CAS Nummer Summenformel Menge
sc-203181 97564-91-5 C₄₇H₇₀O₁₄ 5 µg
Pertussis Toxin (islet-activating protein)
Shown to be a toxin that catalyzes ADP-ribosylation of a protein in membrane preparation. Also reported to block the ability of inhibitory hormones to reduce adenylate cyclase activity.
Katalog # CAS Nummer Summenformel Menge
sc-200837 82248-93-9 n.n. 50 µg
Pertussis Toxin, A Protomer, Bordetella pertussis
Enzymatic component of the holotoxin. Has both NAD-glycohydrolase and ADP-ribosyltransferase activities. Inhibits neutrophil-mediated inflammation in vivo via its ADP-ribosylation activity.
Katalog # CAS Nummer Summenformel Menge
sc-222149 n.n. n.n. 10 µg
Pertussis Toxin, B Oligomer, Bordetella pertussis
The pentameric cell-binding component that is responsible for binding of the holotoxin to eukaryotic cell surfaces, facilitating entry of the A protomer into receptive cells.
Katalog # CAS Nummer Summenformel Menge
sc-222150 n.n. n.n. 40 µg
Phalloidin CruzFluorTM 350 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363789 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 405 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363790 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 488 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363791 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 514 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363792 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 532 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363793 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 555 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363794 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 594 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363795 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 633 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363796 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 647 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363797 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 680 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363798 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 700 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363799 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 750 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363800 n.n. n.n. 300 tests
Phalloidin CruzFluorTM 780 Conjugate
Katalog # CAS Nummer Summenformel Menge
sc-363801 n.n. n.n. 300 tests
Phalloidin, Amanita phalloides
A heptapeptide phallotoxin isolated from Amanita phalloides. Stabilizes filamentous F-actin, interfering with normal cell functioning and inducing cell death.
Katalog # CAS Nummer Summenformel Menge
sc-202763 17466-45-4 C₃₅H₄₈N₈O₁₁S 1 mg
Phomopsin A
Shown to be a potent microtubule inhibitor. Also reported to suppress vinblastine binding and enhance colchicine binding to tubulin.
Katalog # CAS Nummer Summenformel Menge
sc-202282 64925-80-0 C₃₆H₄₅ClN₆O₁₂ 1 mg
Roquefortine C
A potential neurotoxin and a mycotoxin produced by Penicillium roqueforti and P. crustosum. Shown to activate and inhibit detoxification enzymes P-gp and cytochrome P450-3A, respectively.
Katalog # CAS Nummer Summenformel Menge
sc-202323 58735-64-1 C₂₂H₂₃N₅O₂ 500 µg
Sapintoxin D
Fluorescent, highly potent phorbol ester. Useful for membrane studies.
Katalog # CAS Nummer Summenformel Menge
sc-203254 80998-07-8 C₃₀H₃₇NO₈ 1 mg/5 mg
Stachybotrylactam
Unusual spirodihydrobenzofuranlactam mycotoxin shows immunosuppressant and weak HIV protease activity.
Katalog # CAS Nummer Summenformel Menge
sc-202345 163391-76-2 C₂₃H₃₁NO₄ 500 µg
Sterigmatocystin
Inhibitor of DNA synthesis. Mycotoxin produced by strains of the common molds. Induces sister chromatid exchanges in bone marrow cells of mice. Causes necrosis.
Katalog # CAS Nummer Summenformel Menge
sc-222329 10048-13-2 C₁₈H₁₂O₆ 1 mg/5 mg
Syringomycin E
Syringomycin E (SR-E) is a phytotoxin of the cyclic lipodepsinonapeptides class composed of a 3-hydroxy fatty acid tail attached to a polar peptide head that contains nine amino acid residues. It is a potent biosurfactant, which is toxic to many plants and fungi and is implicated as a virulence factor in several major plant diseases such as holcus spot disease of maize and bacterial canker of stone fruits.
Katalog # CAS Nummer Summenformel Menge
sc-215939 124888-22-8 C₅₃H₈₅ClN₁₄O₁₇ 250 µg
Tentotoxin, Alternaria alternata
Tentoxin is a phytotoxic cyclic tetrapeptide which is an inhibitor of chloroplast F1-ATPase (CF1).
Katalog # CAS Nummer Summenformel Menge
sc-222343 28540-82-1 C₂₂H₃₀N₄O₄ 500 µg
Territrem B
A tremorgenic mycotoxin originally derived from a rice culture of Aspergillus terreus and has been shown to be a potent inhibitor of acetylcholinesterase.
Katalog # CAS Nummer Summenformel Menge
sc-203293 70407-20-4 C₂₉H₃₄O₉ 500 µg/1 mg
Tetanolysin
A cytolysin from Clostridium tetani that can be used to permeabilize mammalian cells to macromolecules . Similar to Streptolysin O, but has greater purity and control over pore size. Tetanolysin is reported to induce pores of 20-50 nm, which can be controlled by varying tetanolysin concentration.
Katalog # CAS Nummer Summenformel Menge
sc-222345 61614-31-1 n.n. 100 µg
Tetanus Toxin, C-Fragment, Clostridium tetani
This is the C-terminal binding portion of the heavy chain of tetanus toxin. It is useful for binding studies.
Katalog # CAS Nummer Summenformel Menge
sc-222346 n.n. n.n. 10 µg
Tetanus Toxin, Clostridium tetani
Katalog # CAS Nummer Summenformel Menge
sc-222347 676570-37-9 n.n. 25 µg
Tetanus Toxoid, Clostridium tetani
Katalog # CAS Nummer Summenformel Menge
sc-222348 n.n. n.n. 25 µg
Thaxtomin A
Phytotoxin. Causes plant cell necrosis at nanomolar concentrations. Demonstrated to be produced by bacterial nitric oxide synthases (NOS).
Katalog # CAS Nummer Summenformel Menge
sc-358702 122380-18-1 C₂₂H₂₂N₄O₆ 1 mg/5 mg
Thioacetamide
A hepatotoxin and a carcinogen. An additive in enantioselective reduction of β-keto esters with immobilized bakers' yeast.
Katalog # CAS Nummer Summenformel Menge
sc-213031 62-55-5 CH₃CSNH₂ 25 g
Toxin A, Clostridium difficile
A high molecular weight glucosyltransferase that inhibits small GTPases, such as Rho, Rac, and Cdc42, by glucosylation of a threonine residue. This results in the shutdown of signal transduction cascades, leading to depolymerization of the cytoskeleton, gene transcription of a number of stress-activated protein kinases (SAPKs), and a decrease in the synthesis of phosphatidylinositol 4,5-bisphosphate. This toxin does not require assistance to permeabilize cells, unlike Exoenzyme C3. It also binds to fresh rabbit red blood cells in a hemagglutination assay, and is cytotoxic as determined by a cell rounding assay using human foreskin cells.
Katalog # CAS Nummer Summenformel Menge
sc-222361 n.n. n.n. 2 µg
Toxin B, Clostridium difficile
This is a high molecular weight glucosyltransferase that inhibits small GTPases, such as Rho, Rac, and Cdc42, via glucosylation of a threonine residue. This results in the shutdown of signal transduction cascades, which leads to depolymerization of the cytoskeleton, gene transcription of a number of stress-activated protein kinases (SAPKs), and a decrease in the synthesis of phosphatidylinositiol 4,5-bisphosphate. It may also block serotonin release, and stimulate the production of phospholipases C and D. Due to its ability to affect depolymerization of the cytoskeleton, toxin B has been shown to inhibit biphasic muscle contraction. This toxin does not require assistance to permeabilize cells, unlike Exoenzyme C3. It is cytotoxic as determined in a cell rounding assay using human foreskin cells.
Katalog # CAS Nummer Summenformel Menge
sc-222362 n.n. n.n. 2 µg
(+)-Tubocurarine dichloride
Induces neuromuscular block through interaction with acetylcholine receptor.
Katalog # CAS Nummer Summenformel Menge
sc-202845 57-94-3 C₃₇H₄₂Cl₂N₂O₆ 50 mg