Sigma Receptors and Sigma Ligands

• 4-IBP
  Combines high affinity for σ 1 and moderate affinity for σ 2 sites. Centrally active following systemic administration in vivo.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203779	155798-12-2	C19H21IN2O	10 mg/50 mg

• BD 1008
  Potent and selective σ-ligand.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203426	138356-08-8	C15H22Cl2N2	10 mg/50 mg

• BD 1047 dihydrobromide
  A selective antagonist of σ receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203837	138356-20-4	C13H20CI2N2 ·2HBr	10 mg/50 mg

• BD 1063 dihydrochloride
  A selective antagonist of the σ receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203838	150208-28-9	C13H18Cl2N2 ·2HCl	10 mg/50 mg

• BMY 14802 hydrochloride

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-361126	105565-55-7	C18H22F2N4O.HCl	10 mg/50 mg

• Carbetapentane citrate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203538	23142-01-0	C20H31NO3 ·C6H8O7	100 mg

• Carbetapentane
  A non-opioid sigma site agonist, antitussive and anticonvulsant. Demonstrates neuroprotection against excitotoxicity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201100	77-23-6	C20H31NO3	100 mg/500 mg

• DTG

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203332	97-39-2	C15H17N3	1 g

• (+)-Igmesine hydrochloride

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-362749	130152-35-1	C23H29CN.HCl	10 mg/50 mg

• IPAG
  Potent σ-receptor antagonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204017	n.n.	C17H22IN3	10 mg/50 mg

• L-693,403 maleate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-361222	137730-52-0	C20H23N.C4H4O4	10 mg/50 mg

• METAPHIT
  Acylator of PCP and σ-receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204078	96316-00-6	C18H24N2S	10 mg/50 mg

• N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide
  σ-1 selective ligand which binds with high affinity to human malignant melanoma cells A 2058.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204110	n.n.	C14H19IN2O	10 mg/50 mg

• NE 100 hydrochloride
  Potent, selective σ1 receptor antagonist (K_i = 0.86 nM) that displays > 55 fold selectivity over σ2 receptors and > 6000 fold selectivity over D1, D2, 5-HT1A, 5-HT2 and PCP receptors. Exhibits reversible binding (K_d = 1.2 nM) and displays antipsychotic activity in vivo. Orally active.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204121	149409-57-4	C23H33NO2 ·HCl	10 mg/50 mg

• PB 28 dihydrochloride

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204834	172906-90-0	C24H38N2O•2HCl	10 mg/50 mg

• PD 144418 oxalate
  Selective σ1 ligand displaying high selectivity. Exhibits no other significant activity at a wide range of other receptors, ion channels, and enzumes. Following i.p. administration, antagonizes mescaline-induced scratching in mice.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204164	154130-99-1	C18H22N2O•C2H2O4	10 mg/50 mg

• 4-PPBP maleate
  σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203780	207572-62-1	C21H27N ·C4H4O4	10 mg/50 mg

• (+/-)-PPCC oxalate
  (±)-PPCC oxalate is a selective sigma (σ) receptor ligand which is noted to exhibit high affinity for σ1 and also binds at σ2 sites

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-358806	932736-90-8	C24H29NO3•C2H2O4	10 mg/50 mg

• PRE-084 Hydrochloride
  High affinity, selective σ1 agonist. Selective over PCP receptors and several other receptor systems. Produces antiamnesic and antitussive effects in vivo.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203447	138847-85-5	C19H27NO3··HCl	10 mg/50 mg

• Rimcazole dihydrochloride
  Binds to the dopamine transporter (IC₅₀ = 57.6 nM) and inhibits dopamine uptake. Antagonist at σ receptors (IC₅₀ values are 1480 and 386 nM at σ1 and σ2 receptors respectively). Reduces the stimulatory effects of cocaine in vivo.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204236	75859-03-9	C21H27N3•2HCl•H2O	10 mg/50 mg

• (+)-SK&F 10047 hydrochloride
  Prototypical σ1 receptor agonist. Behaviorally active in animal models of memory and stress.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204282	133005-41-1	C17H23NO•HCl•xH2O	10 mg/50 mg

• TC 1
  High affinity σ1 receptor ligand that displays selectivity over σ2 receptors (Ki values are 10 and 370 nM respectively). Exhibits low affinity for dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters (Ki > 10 μM). Low affinity for dopamine D2 receptors (Ki = 1226 nM). Attenuates cocaine-induced locomotor activity in mice.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204323	n.n.	C19H20FNO	10 mg/50 mg