Platelet Activating Factors

• 1-Acyl-PAF
  The predominant PAF species produced by stimulated endothelial cells. This compound induces IL-6 release in rat anterior pituitary cells in vitro and the compound also displays protective effects in oxidative stress.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205565	84062-61-3	C26H52NO8P	1 mg/5 mg

• 1-O-Hexadecyl-2-O-arachidonoyl-sn-glycero-3-phosphorylcholine
  A phospholipid biosynthetic precursor of platelet-activating factor (PAF). Used to examine substrate dependence and the effect on deacylation of alkylarachidonoyl-GPC by platelet phospholipase A2.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201013	86288-11-1	C44H82NO7P	5 mg/25 mg

• 1-O-Hexadecyl-2-O-eicosapentaenoyl-sn-glycero-3-phosphorylcholine
  A biosynthetic precursor of PAF via the lipid remodeling pathway1.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205566	n.n.	C44H80NO7P	5 mg/25 mg

• 12-OxoETE
  12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via an Leukotriene B4 receptor or a common activation sequence

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204611	108437-64-5	C20H30O3	25 µg/50 µg

• Clopidogrel hydrogen sulfate
  An ADP receptor antagonist that inhibits the aggregation of platelets.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204693	135046-48-9	C16H16ClNO2S ·H2SO4	500 mg/1 g

• Enantio-PAF C-16
  Initiates receptor-mediated responses in platelets and a variety of other cells. A biologically inactive enantiomer of PAF.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201023	117985-57-6	C26H54NO7P	1 mg/5 mg

• Lyso-PAF (C18)
  Substrate for PAF C-18 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203123	74430-89-0	C26H56NO6P	5 mg/50 mg

• Lyso-PAF C-16
  A metabolite of the platelet-activating factor (PAF) that has been used to study PAF synthesis. Generated by the activity of a coenzyme A-independent transacylase.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201011	52691-62-0	C24H52NO6P	5 mg/25 mg

• Lyso-PAF C-18-d4

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-358884	n.n.	C26H52D4NO6P	100 µg/500 µg

• PAF (C18) Propionyl-
  2-fold more potent analog than PAF. Pathological processes involving PAF include necrotizing enterocolitis, 4 inflammation, asthma, and allergy. PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and enhances the spreading of plated macrophages.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205961	n.n.	C29H60NO7P	1 mg

• PAF C-16
  PAF C-16 is a platelet activating factor(PAF) with a C16 alkane group. It acts as an extracellular signaling lipid.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201009	74389-68-7	C26H54NO7P	5 mg/25 mg

• PAF C-16-d4
  Contains four deuterium atoms at the 7, 7', 8, and 8' positions of the hexadecyl moiety and is intended for use as an internal standard for the quantification of PAF C-16 by GC- or LC-mass spectrometry. PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways.1 It is a potent mediator of neutrophil migration,2 the production of reactive oxygen species,3 and IL-64 in human macrophages and is a more potent mediator of platelet aggregation than PAF C-185. Pathological processes involving PAF include necrotizing enterocolitis,6 inflammation, asthma, and allergy.7

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-224198	n.n.	C26H50D4NO7P	100 µg/500 µg

• PAF C-18
  A naturally occurring 18-carbon chain phospholipid PAF and ligand at the PAF receptor. Induces human neutrophil chemotaxis, platelet aggregation, hypotension and bronchoconstriction.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201017	79549-26-1	C28H58NO7P	5 mg/25 mg

• PAF C-18:1
  A platelet activating factor shown to cause platelets to aggregate, change shape, and release granular contents.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201019	85966-90-1	C28H56NO7P	5 mg/25 mg