Platelet Activating Factor (PAF) Receptor Agonists and Antagonists

• 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phospho-(N,N,N-trimethyl)-hexanolamine
  PAF antagonist. Shows inhibitory behavior on platelet aggregation, secretion and phospholipid turnover.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202862	99103-16-9	C30H62NO7P	5 mg/25 mg

• Araguspongin B
  Products isolated from Pacific basin sponges with notable vasodilatory properties. Serve as important signal transduction messengers acting to promote transfer of Ca²⁺ from intracellular stores. Shown to exhibit an antagonizing effect of the calcium-releasing action of inosital 1,4,5-triphosphate at receptor levels in cerebral microsomes.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205215	123000-02-2	C28H50N2O2	100 µg/250 µg

• Bis(methylthio)gliotoxin (FR-49175)
  Analog of gliotoxin shown to inhibit PAF-induced platelet aggregation and speed up PAF hydrolysis.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201027	74149-38-5	C15H20N2O4S2	1 mg/5 mg

• C-PAF (Carbamyl-PAF )
  C-PAF (Carbamyl-PAF) is utilized as a non-hydrolyzable bioactive analog of PAF.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201025	91575-58-5	C26H55N2O7P	5 mg/25 mg

• (±) cis-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane
  Inactive enantiomer of (±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane, a PAFr inhibitor. Useful as a negative control.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201031	116673-47-3	C21H26O8	1 mg/5 mg

• CV-3988
  A specific antagonist of PAF binding to the PAF receptor. Inhibits PAF-induced platelet aggregation.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201015	85703-73-7	C28H53N2O7PS	5 mg/25 mg

• Eptifibatide
  A selective inhibitor of platelet glycoprotein IIb/IIIa receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205675	148031-34-9	C35H49N11O9S2	5 mg/10 mg

• ET-18-OCH3
  An ether lipid analogue that induces selective apoptosis in tumor cells without affecting normal cells. Agent has ability activate intracellular Fas/CD95 and inhibit activation of p70S6K.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201021	77286-66-9	C27H58NO6P	5 mg/25 mg

• Ginkgolide B (BN 52021)
  Most potent member of ginkgolide family of PAF antagonists. Has been found to accelerate PAF hydrolysis by promoting PAF-AH I α₂ homodimer activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201037	15291-77-7	C20H24O10	10 mg/50 mg

• PCA 4248
  A dihydropyridine that inhibits PAF in a competitive manner at the PAF receptor level. Shown to also reduce serotonin secretion caused by PAF.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203446	123875-01-4	C19H23NO4S	10 mg/50 mg

• Octylonium Bromide
  Reported to antagonize platelet-activating factor induced aggregation of rabbit platelet-rich plasma. Demonstrates the ability to potently block neuronal nicotinic acetylcholine receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201035	26095-59-0	C29H43N2O4Br	5 mg/25 mg

• (±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane
  (±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane is a selective and potent platelet activating factor (PAF) antagonist of the diaryl tetrahydrofuran class. Reported to block LTP in field CA1 in rat hippocamp

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201029	116673-45-1	C21H26O8	1 mg/5 mg

• WEB-2086
  WEB-2086 (Apafant) is a Platelet Activating Factor (PAF) receptor antagonist shown to have anticancer and cell differentiation effects.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201007	105219-56-5	C22H22ClN5O2S	1 mg/5 mg