| | Nitric Oxide Donors
- (2S)-(+)-Amino-6-iodoacetamidohexanoic acid
An irreversible inhibitor of ornithine decarboxylase and arginase.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-220847 | 35748-65-3 | C8H15N2O3I | 5 mg |
- 3-Morpholinosydnonimine (SIN-1)
A potent vasodilator, inhibitor of platelet aggregation, general cysteine protease inhibitor, and has been shown to produce significant protective effects in myocardial ischemia-reperfusion.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200339 | 33876-97-0 | C6H10N4O2··HCl | 20 mg/100 mg |
- 4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate
A member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer.1| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-223600 | n.n. | C9H9NO3S | 5 mg/10 mg |
- 4-chloro-4-phenyl-1,3,2-Oxathiozolylium-5-olate
A member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer.1| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-223631 | n.n. | C8H6ClNO2S | 5 mg/10 mg |
- 4-phenyl-1,3,2-Oxathiazolylium-5-olate
A member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions.1| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-223664 | n.n. | C8H7NO2S | 5 mg/10 mg |
- 4-trifluoro-4-phenyl-1,3,2-Oxathiazolylium-5-olate
A member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer.1| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-223666 | n.n. | C9H6F3NO2S | 5 mg/10 mg |
- 4AF DA
Negative control compound for the fluorescent probes DAF-2.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221000 | n.n. | C24H17NO7 | 1 mg |
- ABH ammonium salt
A strong and specific inhibitor of arginase. Does not inhibit NO synthases.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221197 | n.n. | C6H13BNO4 ·NH4 | 1 mg |
- AMI-1
A potent, cell permeable and specific inhibitor of protein arginine N-methyltransferases (PRMTs).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205928 | n.n. | C21H12N2O9S2Na4 | 5 mg/25 mg |
- Angeli’s Salt
A nitroxyl anion (NO–) donor that spontaneously dissociates in a pH dependent first order process to liberate 0.54 moles of NO per mole of the parent compound.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202464 | 13826-64-7 | Na2N2O3 | 10 mg |
- BEC
A potent slow-binding competitive inhibitor of recombinant rat liver arginase I (Ki of 0.4-0.6 µM) and human arginase II (Kii values of 0.31 µM and 30 nM at pH 7.5 and 9.5).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205220 | 63107-40-4 | C5H12BNO4S | 1 mg/5 mg |
- BEC ammonium salt
A slow-binding competitive inhibitor of arginase I and arginase II; enhances NO-dependent smooth muscle relaxation in human penile corpus cavernosum tissue.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221290 | 63107-40-4 (free base) | C5H11BNO4S•NH4 | 1 mg/5 mg |
- β-Gal NONOate
Nitric oxide donor. Glycosylated, cell permeable in vivo nitric oxide releasing compound.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202861 | 357192-78-0 | C10H19N3O7 | 1 mg/5 mg |
- BNN3
Cell permeable, photolabile NO donor. Two NO molecules per molecule of BNN3 released upon irradiation.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202977 | 6947-38-2 | C8H10N4O2 | 1 mg |
- DAF-2 DA (cell permeable)
Cell permeable analog of DAF-2 that is hydrolyzed to DAF-2 by intracellular esterases. Can be used in fluorescence microscopy to measure real-time changes in nitric oxide (NO) levels in vivo. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221526 | 205391-02-2 | C24H18N2O7 | 1 mg |
- DAF-FM DA (cell permeable)
An analog of DAF-FM that is cell permeable and can be hydrolyzed to DAF-FM via intracellular esterases. Photostable and stable in pH 5.5 to 12.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205940 | 254109-22-3 (solid) | C25H18F2N2O7 | 1 mg |
- DAN-1 EE hydrochloride
Fluorescent indicator for the bioimaging of nitric oxide (NO). Upon entry into the cell, DAN-1 EE is transformed by cytosolic esterases into the less cell permeable DAN-1. Intracellular formation of NO can be monitored.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221528 | n.n. | C20H20N2O2•HCl | 5 mg |
- DD1
Cell permeable thiol-induced nitric oxide donor with strong vasodilator effects.Guanylyl cyclase activator. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221531 | n.n. | C5H9BrN2O2 | 10 mg/50 mg |
- DD2
Cell permeable thiol-induced nitric oxide donor with strong vasodilator effects.Guanylyl cyclase activator. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221532 | n.n. | C7H11BrN2O2 | 10 mg/50 mg |
- Diethylamine NONOate
A diazeniumdiolate NO donor with a half-life of 16 min at 22-25°C.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202575 | 56329-27-2 | C8H22N4O2 | 10 mg |
- DL-α-Difluoromethylornithine hydrochloride hydrate
This inhibits polyamine biosynthesis by selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-252762 | 96020-91-6 | C6H12F2N2O2 ·xHCl ·yH2O | 25 mg |
- DPTA NONOate
A diazeniumdiolate small molecule NO donor with a half-life of 5 hr at 22-25°C.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202144 | 146724-95-0 | C6H17N5O2 | 5 mg/25 mg |
- Ethyl-L-NIO, hydrochloride
The saturated analog of vinyl-L-NIO; is a modestly selective NOS inhibitor. Although ethyl-L-NIO inhibits nNOS, it does not inactivate nNOS in the presence of NADPH and O2.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-223979 | 150403-97-7 | C9H19N3O2 ·HCl | 5 mg/10 mg |
- Fructose-SNAP-1
Nitric oxide (NO) donor with increased cytotoxicity compared to SNAP. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221631 | n.n. | C13H23N3O8S | 5 mg |
- GEA 3162
Water soluble nitric oxide donor and potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203055 | 144575-47-3 | C7H4Cl2N4O | 10 mg/50 mg |
- GEA 5024
Water soluble and stable nitric oxide donor.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203056 | 144575-27-9 | C8H7ClN4O•HCl | 10 mg/50 mg |
- Geranylgeranylacetone
Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as hypoxic/ischemic brain injury, inflammatory bowel disease and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Recent reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA "can induce expression of HSPB8 and HSPB1 as well as reduce the formation of amyloid oligomers and insoluble aggregates in HSPB5 R120G TG mice."| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-252851 | 6809-52-5 | C23H38O | 10 mg/100 mg |
- GEA 5583
Stable nitric oxide releasing compound that is orally absorbed in rats.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205946 | n.n. | C11H9ClN6O2 | 10 mg/50 mg |
- Guanylyl Cyclase, Soluble (bovine)
| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221697 | n.n. | n.n. | 5 µg |
- GYY 4137
| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-224013 | 106740-09-4 | C11H16NO2PS2 ·C4H10NO | 10 mg/25 mg |
- Hydroxyguanidine hemisulfate
Structural analog of NG-hydroxy-L-arginine that potentiates and stabilizes the relaxant effect of nitric oxide.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-221734 | 6345-29-5 | C2H10N6O2•H2SO4 | 25 mg |
- Hydroxyguanidine sulfate
A substrate found in endothelial cells that reacts with nitric oxide to produce a vasodilating compound.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200341 | 13115-21-4 | CH5N3O ·0.5H2SO4 | 5 mg/25 mg |
- JS-K
An antiproliferative nitric oxide donor.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-211683 | 205432-12-8 | C13H16N6O8 | 5 mg/25 mg |
- L-NIL dihydrochloride
A relatively selective inhibitor of iNOS where it exhibits IC50 values of 3.3 and 92 µM for iNOS (murine) and nNOS (rat).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205362 | 159190-45-1 | C8H17N3O2 ·2HCl | 5 mg/10 mg |
- MEG (sulfate)
A selective scavenger of peroxynitrite and iNOS inhibitor; exhibits potent anti-inflammatory activity.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205381 | 3979-00-8 | [C3H9N3S]2 ·H2SO4 | 5 mg/10 mg |
- Methyl-L-NIO (hydrochloride)
A competitive NOS inhibitor that competes with L-arginine for the amino acid binding site. A more potent inhibitor of nNOS.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205389 | 150403-96-6 | C8H17N3O2•HCl | 5 mg/10 mg |
- Molsidomine
Molsidomine is a long-lasting, NO releasing vasodilator. It requires hepatic metabolism to be active, but causes no pharmacological tolerance.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200337 | 25717-80-0 | C9H14N4O4 | 50 mg/250 mg |
- N-Acetyl-D,L-penicillamine disulfide
Degradation product of S-nitroso-N-acetyl-D,L-penicillamine (SNAP)| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205957 | n.n. | C14H24N2O6S2 | 1 mg/5 mg |
- N-Cyclopropyl-N'-hydroxyguanidine hydrochloride
Selective substrate for nNOS (NOS I). 70% nitric oxide (NO) formation for nNOS (NOS I), 26% for eNOS (NOS III) and <0.5% for iNOS (NOS II) when compared to NO formation using NG-Hydroxy-L-arginine as a substrate.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-222000 | 551935-92-3 | C4H9N3O•HCl | 1 mg/5 mg |
- NOC-12
A diazeniumdiolate NO donor, releases NO with a half-life of 327 min at 22°C. Demonstrates NO-induced increases of cGMP levels and protection of cells against H2O2-induced damage and reperfusion.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202246 | 146724-89-2 | C6H16N4O2 | 10 mg |
- NOC-18
A diazeniumdiolate NO donor, releases NO with a half-life of 20 hr. Shown to prevent Cu2+ LDL peroxidation.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202247 | 146724-94-9 | C4H13N5O2 | 10 mg |
- NOC-5
NO donor. A stable NO-amine complex that can spontaneously release two equivalents of NO in solution under physiological conditions without any cofactor. Relatively stable in pH ≥10.0.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202248 | 146724-82-5 | C6H16N4O2 | 10 mg |
- NOC-7
Nitric oxide (NO) donor similar to NOC-5 but with a much shorter half-life of NO release. Useful as a short-acting nitrovasodilator. Relatively stable in alkaline solution (pH ≥10.0).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202249 | 146724-84-7 | C5H14N4O2 | 10 mg |
- NOC-9
A diazeniumdiolate NO donor, releases NO with a half-life of 2.7 min. Demonstrates NO-induced activation of skeletal muscle Ca2+ channel activity.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202250 | 146724-86-9 | C8H20N4O2 | 10 mg |
- NOR-1
A novel non-thiol-based NO donor which releases NO under physiological conditions with a half-life of 1.7 minutes. Inhibits cysteine proteases. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202736 | 163032-70-0 | C8H13N3O5 | 10 mg |
- NOR-2
Nitric oxide (NO) donor| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202737 | 163032-71-1 | C7H11N3O4 | 5 mg/10 mg |
- NOR-3
Cell-permeable, non-thiol, NO donor that can spontaneously release NO in a rate controlled manner (half-life (t½) in PBS, pH 7.4 is 30 minutes at 37°C) generating biologically inactive by-products. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202738 | 163180-49-2 | C8H13N3O4 | 5 mg/10 mg |
- NOR-4
A NO donor compound with a half-life NO release of 340 minutes.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202739 | 163180-50-5 | C14H18N4O4 | 5 mg/10 mg |
- NOR-5
This is a Nitric oxide (NO) donor. It has a half-life time of 0.5mM, NOR-5 is 20 hours at 37°C in 0.1M PBS, pH 7.4.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-222076 | n.n. | C16H22N4O4 | 5 mg/10 mg |
- PAPA NONOate
A diazeniumdiolate NO donor with a half-life of 77 min at 22-25°C.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202272 | 146672-58-4 | C6H16N4O2 | 5 mg/25 mg |
- Piloty’s Acid
One of the best known and most commonly used HNO donors; decomposes to HNO and benzenesulfinate anion under basic conditions.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205436 | 599-71-3 | C6H7NO3S | 500 mg/1 g |
- PROLI NONOate
This is a Nitric oxide (NO) donor. This product dissociates with extreme rapidity to proline (1mol) and NO (2mol). This type of behavior allows the generation of highly localized anti-platelet and vasodilatory effects. The decomposition of NONOates is nearly instantaneous at pH 5.0. The half life in 0.1M phosphate buffer, pH 7.4 at 37°C is 1.8s.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-222190 | n.n. | C5H7N3O4•2Na | 10 mg/25 mg |
- Rebamipide hydrate
An anti-ulcer agent with free-radical scavenging and anti-inflammatory effects. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-258085 | 90098-04-7 (anhydrous) | C19H15ClN2O4•xH2O | 5 mg |
- (±)-S-Nitroso-N-acetylpenicillamine (SNAP)
A cysteine protease inhibitor and NO donor which spontaneously releases NO under physiological conditions. SNAP is a potent vasodilator in vitro and inhibits vascular smooth muscle cell mitogenesis and proliferation.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200319 | 79032-48-7 | C7H12N2O4S | 20 mg/100 mg |
- S-Nitrosoglutathione (GSNO)
NO donor. Spontaneously releases NO under physiological conditions. Inhibits platelet activation and displays cardioprotective effects. Inhibits NF-κB activation and endothelial cell proliferation. Shows a dose dependent effect on Thymocyte apoptosis.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200349 | 57564-91-7 | C10H16N4O7S | 10 mg/50 mg |
- SE 175
An organic nitrate compound of the same general class as nitroglycerin; can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205506 | 258278-64-7 | C16H13NO6S | 5 mg/10 mg |
- SIN-1A/γCD Complex
A physiologically active nitric oxide (NO) releasing agent. Releasing one equivalent of NO the half life time at
room temperature is ~40 minutes mostly independent from the pH.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205975 | 26687-79-6 (SIN-1A) | n.n. | 5 mg/25 mg |
- SNAP
An S-nitrosothiol which serves as a NO donor and a potent vasodilator. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content. At pH 6-8 and 37°C, the half-life of SNAP is approximately six hours in the presence of transition metal ion chelators.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205510 | 67776-06-1 | C7H12N2O4S | 10 mg/25 mg |
- Sodium Nitroprusside, Dihydrate
A nitric oxide donor/releaser, that has been reported to reduce lipid peroxidation-induced membrane damage.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203395 | 13755-38-9 | Na2[Fe(CN)5]NO ·2H2O | 100 mg/5 g/100 g |
- Spermine NONOate
A spermine-derived diazenium diolate NO donor. Half-lives of NO release are 230 minutes at 22 °C and 39 minutes at 37 °C.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202816 | 136587-13-8 | C10H26N6O2 | 5 mg/25 mg |
- Streptozotocin (U-9889)
A potent DNA methylating small molecule, particularly active in pancreatic cells.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200719 | 18883-66-4 | C8H15N3O7 | 1 g/5 g |
- Sulfo-NONOate disodium salt
A donor of nitrous oxide (N2O) with a release half-life of ~32 min at 22-25°C (diammonium salt). Useful as a negative control for NO-release studies employing NONOates.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-202348 | 61142-90-3 | N2O5S ·2Na | 5 mg/25 mg |
- Tetrahydrobiopterin (THB) dihydrochloride
An activating Nitric Oxide Synthase cofactor used in a variety of applications. The compound is an activating cofactor for monoxygenases and used to study the effect of internal and external THB stores.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200345 | 17528-72-2 | C9H15N5O3 ·2HCl | 25 mg/100 mg |
- V-PYRRO/NO
A NO donor in vivo where following hepatic metabolism, it spontaneously decomposes with a half-life of 3 seconds to liberate NO.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205538 | 179344-98-0 | C6H11N3O2 · ·C6H11N3O2 | 5 mg/10 mg |
- Vinyl-L-NIO (hydrochloride)
A potent, selective inhibitor of nNOS; in the presence of NADPH and O2 it irreversibly inactivates nNOS.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205541 | 728944-69-2 | C9H17N3O2 ·HCl | 5 mg/10 mg |
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