Neurobiology and Neurodiseases

• (±)-2-Methylarachidonoyl-2'-fluoroethylamide
  An analog of arachidonylethanolamide that is a strong, selective CB1 cannabinoid receptor agonist. The methyl group at the C-2 position of arachidonic acid enhances the metabolic stability of the compound. It can fully substitute for 9-THC in animal self-administration tests.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-251783	166100-39-6	C23H38NOF	5 mg

• (2S,3S)-3-Methylglutamic Acid Hydrochloride Salt
  A potent agonist for kainate receptors. Is highly selective.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216336	n.n.	C6H12ClNO4	5 mg

• (2S,3S)-trans-3-(Carboxymethyl)-azetidine-2-acetic Acid
  Effective inhibitor of sodium dependent glu uptake and KA receptor agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-206577	185387-36-4	C6H9NO4	5 mg

• (-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane
  This compound inhibits the serotonin (5-HT) transporter.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-206587	136794-87-1	C15H18INO2	500 µg

• (-)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, HCl
  A dopamine antagonist. A dopaminergic ligand. This compound has been used as a precursor for the PET radiotracer, 11C-(-)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216586	n.n.	C12H16ClNO2	5 mg

• (-)-3,4,4a,5,6,10b-Hexahydro-9-methoxy-2H-naphtho[1,2-b][1,4]oxazin-3-one
  A dopamine antagonist and dopaminergic ligand.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216587	n.n.	C13H15NO3	5 mg

• (+)-3,4,4a,5,6,10b-Hexahydro-9-methoxy-2H-naphtho[1,2-b][1,4]oxazin-3-one
  A dopamine antagonist and a dopaminergic ligand.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216588	153153-60-7	C13H15NO3	5 mg

• (-)-3,4,4a,5,6,10b-Hexahydro-9-methoxy-2H-naphtho[1,2-b][1,4]oxazin, HCl
  A dopamine antagonist and dopaminergic ligand.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216589	n.n.	C13H18ClNO2	5 mg

• (+)-3,4,4a,5,6,10b-Hexahydro-9-methoxy-2H-naphtho[1,2-b][1,4]oxazin, HCl
  A dopamine antagonist and dopaminergic ligand.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216590	n.n.	C13H18ClNO2	5 mg

• 4-Benzoylpiperidine Hydrochloride
  Synthetic intermediate in the preparation of CNS depressants.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216783	25519-80-6	C12H16ClNO	100 mg

• 4-Formylphenyl b-D-allopyranoside

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-277405	80154-34-3	C13H16O7	1 g/5 g

• 5-Chloro Bifeprunox Mesylate
  Used as an antipsychotic compound. Activates the serotonin 5-hydroxytryptamine (5-HT)1A receptor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-217164	n.n.	C25H26ClN3O5S	25 mg

• 5-Fluoro-2'-deoxycytidine
  Mechanism-based DNMT inhibitor, shown to form covalent links with the cysteine residue in the DNMT active site.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252267	10356-76-0	C9H12FN3O4	5 mg

• 6-Iodonordihydrocapsaicin
  TRPV1 (V1) vanilloid receptor antagonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252297	859171-97-4	C17H26INO3	5 mg

• 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione, Disodium Salt
  A discriminating and potent antagonist for AMPA binding sites.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-217370	479347-86-9	C12H6N4Na2O6S	5 mg

• 9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol Maleate
  Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-207210	113108-86-4	C24H24N2O5	100 mg

• α-Methadol-d3
  An analgesic, labeled reduction product of Methadone.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-220441	n.n.	C21H26D3NO	1 mg

• AC-93253 iodide
  A potent, cell permeable, subtype selective RAR agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-257044	108527-83-9	C23H25N2SI	10 mg/50 mg

• Angiotensin II, Human

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-363643	4474-91-3	n.n.	1 mg/5 mg

• Arachidonyl-2'-chloroethylamide hydrate
  A potent and selective neuronal CB1 cannabinoid receptor agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252384	220556-69-4 (anhydrous)	C22H36ClNO	25 mg

• BATCP
  HDAC 6 selective substrate (over HDAC 1, Class II over Class I).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252405	787549-23-9	C23H28F3N3O6	2 mg

• BAY U6751 hydrate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-257117	114290-51-6 (anhydrous)	C20H20ClNNa2O6•xH2O	5 mg

• Benztropine mesylate
  A derivative of Atropine and an antagonist of the mAChR which also demonstrates anti-nicotinic action at the nAChR.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202495	132-17-2	C21H25NO ·CH4SO3 ·H2O	1 g/5 g

• Bretazenil
  A benzodiazepine partial agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252512	84379-13-5	C19H20N3O3Br	5 mg

• Carbasalate calcium

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-278809	5749-67-7	C19H18CaO9N2	20 mg

• Citral

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252620	5392-40-5	C10H16O	1 kg

• CPTH2
  CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network where HATs act as transcriptional coactivators. Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-255032	357649-93-5	C14H14ClN3S	5 mg

• Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly
  SV40 T-antigen homolog that can induce nuclear transport.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-257276	104914-40-1	C60H104N20O15S	500 µg

• Cytosporone B
  The first naturally occurring agonist for nuclear orphan receptor Nur77 is Cytosporone B. The molecule binds with high affinity (IC₅₀=0.278 nM) to the ligand-binding domain of Nur77 and stimulates Nur77-dependent activities. Nur77 is a nuclear receptor/transcription factor. A physiological ligand for Nur77 is as yet unknown, but there is increasing interest in Nur77 because of its known activities. Translocation of Nur77 from the nucleus to mitochondria initiates cell apoptosis, making it a potential target for cancer treatment. Nur77 is also involved in glucose homeostasis, where it induces genes involved in gluconeogenesis. Csn-B physically binds to Nur77 and activates its transactivational activity and translocation to mitochondria to induce apoptosis. It inhibits cancer cell proliferation and tumor growth.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252653	321661-62-5	C18H26O5	5 mg

• D-α-Tocotrienol
  Widely used for their strong antioxidant properties. The various isoforms of tocotrienols differ in their methyl substitution in the chromanol head. α-tocotrienol demonstrates neuroprotective properties by blocking glutamate-induced cell death in neuronal cells.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252656	1721-51-3	C29H44O2	10 mg

• D,L N-Desmethyl Venlafaxine
  A metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-207483	149289-30-5	C16H25NO2	5 mg

• D,L N,O-Didesmethyl Venlafaxine
  A metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-207484	135308-74-6	C15H23NO2	5 mg

• D,L N,O-Didesmethyl Venlafaxine-d3
  A deuterium-labeled metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine with reported weak inhibitory effect on dopamine reuptake.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218040	n.n.	C15H20D3NO2	1 mg

• D,L-N-Desmethyl Venlafaxine-d3
  A deuterium-labeled metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218052	n.n.	C16H22D3NO2	1 mg

• D,L-N,N-Didesmethyl Venlafaxine-d6
  A deuterium-labeled metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218053	n.n.	C15H17D6NO2	1 mg

• D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine
  An impurity of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218054	n.n.	C24H33NO3	10 mg

• D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine Hydrochloride
  A metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-211199	135308-76-8	C14H21NO2•HCl	2.5 mg

• D,L-O-Desmethyl Venlafaxine
  A metabolite of the serotonin and noradrenaline reuptake inhibitor Venlafaxine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-207494	93413-62-8	C16H25NO2	5 mg

• D,L-O-Desmethyl Venlafaxine-d6
  A deuterium-labeled metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218055	n.n.	C16H19D6NO2	1 mg

• Dansyl-NECA
  Fluorescent ligand for adenosine receptors with a marked selectivity for the A1 receptor subtype. Has been successfully applied in fluorescence microscopy assays.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202570	219982-12-4	C30H40N8O6S	500 µg

• DCHC
  A SIRT1 activator which increases peroxisome proliferator-activated receptor gamma co-activator 1å (PGC1å) expression, resulting in mitochondrial biogenesis. Activates SIRT1 at low micromolar concentrations and increases SIRT1 activity at 100 µM. It induces the activation of recombinant SIRT1, but does not increase SIRT1 expression.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-255067	302953-06-6	C15H8Cl2O3	10 mg

• Dehydro Venlafaxine
  A degradation product of the neuroamine reuptake inhibitor Venlafaxine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-211230	93413-57-1	C17H25NO•HCl	1 mg

• Deoxy Venlafaxine
  An impurity of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218117	n.n.	C17H27NO	1 mg

• Desethylene Aripiprazole
  A derivative of Aripiprazole.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218138	1216394-63-6	C21H25Cl2N3O2	1 mg

• Dimebolin

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-278972	3613-73-8	C21H25N3	25 mg

• Dimethyl Cabergoline
  An analogue of Cabergoline.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218234	n.n.	C28H41N5O2	10 mg

• DM 235
  Potent nootropic agent.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300499	314728-85-3	C14H18N2O2	5 mg

• Donepezil
  A noncompetitive acetylcholineesterase inhibitor, which can readily cross the blood brain barrier and increases the concentration of cortical acetylcholine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279006	120014-06-4	C24H29NO3	10 mg

• Donepezil Hydrochloride
  A noncompetitive acetylcholineesterase inhibitor, which can readily cross the blood brain barrier and increases the concentration of cortical acetylcholine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218265	120011-70-3	C24H30ClNO3	10 mg

• Doxapram

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279007	309-29-5	C24H30N2O2	5 mg

• Doxapram hydrochloride

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279008	113-07-5	C24H31ClN2O2	5 mg

• Droxidopa

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279010	23651-95-8	C9H11NO5	100 mg

• Duloxetine

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279011	116539-59-4	C18H19NOS	10 mg

• (-)-Eseroline fumarate
  Metabolite of physostigmine (eserine). Potent analgesic.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202155	104015-29-4	C13H18N2O ·C4H4O4	10 mg/50 mg

• Ethyl gallate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-239928	831-61-8	C9H10O5	100 g

• Fadrozole hydrochloride
  Nonsteroidal aromatase inhibitor exhibiting a very potent and selective inhibitory effect of the aromatase enzyme system in vivo and estrogen biosynthesis in vivo.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252819	102676-31-3	C14H13N3 ·HCl	10 mg

• FH535
  FH535 is a reversible dual inhibitor of Wnt/β-catenin and PPARγ and PPARδ signaling antagonist; β-catenin/Tcf inhibitor. FH535 has been shown to inhibit the Wnt/b-catenin pathway. The compound is selectively toxic to some carcinomas expressing the Wnt/B-catenin pathway. FH535 is a more potent Wnt/h-catenin inhibitor than NO-aspirin.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300691	108409-83-2	C13H10Cl2N2O4S	5 mg

• FIPI hydrochloride hydrate
  A potent inhibitor of PLD (phospholipase D) specifically PLD 1 and PLD 2. FIPI hydrochloride hydrate can block the production of phosphatidic acid with subnanomolar potency.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300694	n.n.	C23H24FN5O2 ·HCl ·xH2O	5 mg

• Fluoxetine
  A 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279166	54910-89-3	C17H18F3NO	500 mg

• Fluoxetine HCl
  A 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201125	56296-78-7	C17H18F3NO•HCl	50 mg/250 mg

• Fluoxetine-d5 Hydrochloride
  A deuterium-labeled 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218509	56296-78-7 (unlabeled)	C17H14D5ClF3NO	1 mg

• Fluphenazine
  A neuroleptic drug that is a dopamine receptor antagonist. Acts as an antimutagen, which may be explained by its ability to reduce the level of free radicals.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205700	69-23-8	C22H26F3N3OS	1 g/5 g

• Fluphenazine decanoate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279167	5002-47-1	C32H44F3N3O2S	10 mg

• fluphenazine enanthate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279168	2746-81-8	C29H38F3N3O2S	10 mg

• Gabapentin Related Compound B
  A Gabapentin analogue used in the treatment of neurological disorders.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-211550	133481-09-1	C9H13NO2	2.5 mg

• Gabapentin Related Compound D
  A Gabapentin analogue.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218552	1076198-17-8	C18H29NO3	5 mg

• Gabapentin Related Compound E
  A Gabapentin analogue.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-211551	67950-95-2	C9H14O4	10 mg

• Gly-Pro-Glu
  Gly-Pro-Glu is a neuroprotective compound and the N-terminal tripeptide of IGF-1. Gly-Pro-Glu is neuroprotective after central administration in animal models of neurodegenerative processes, such as Huntington's, Parkinson's, Alzheimer's diseases, and varies acute brain injury animal models. The neuroprotective activity is not related to its affinity to glutamate receptor. Findings indicate that GPE mimics insulin-like growth factor I effects on the somatostatin system through a mechanism independent of β-amyloid clearance that involves modulation of calcium and glycogen synthase kinase 3β signaling.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252859	32302-76-4	C12H19N3O6	10 mg

• HR-73
  HR-73 is a splitomycin derivative and a SIRT1 inhibitor. HR-73 induces p53 hyperacetylation and decreases HIV transcription.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-255207	959571-93-8	C19H13BrO2	5 mg

• Hypaconitine
  A diterpene alkaloid isolated from Aconiti Carmichaeli Praeparata which is a neuromuscular blocker.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205717	6900-87-4	C33H45NO10	10 mg/25 mg

• IIK7
  IIK7 is a melatonin receptor agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300823	n.n.	C22H24N2O2	1 mg

• iso-Talipexole, Dihydrochloride
  An analogue of Talipexole, an alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-280851	n.n.	C10H17Cl2N3S	50 mg

• IWP-2
  Inhibits Wnt production; useful in both regenerative medicine and anticancer efforts.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252928	686770-61-6	C22H18N4O2S3	5 mg

• JNJ 17203212

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300853	n.n.	C17H15F6N5O	5 mg

• JZL 184 hydrate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300854	n.n.	C27H24N2O9•xH2O	5 mg

• K 185
  K 185 is a melatonin receptor antagonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300855	32223-82-8	C24H28N2O2	1 mg

• KH7
  A selective peptide inhibitor of soluble adenylyl cyclase and transepithelial Na⁺ current.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252933	330676-02-3	C17H15BrN4O2S	5 mg

• (±)-L-Alliin
  Sulfur-containing amino acid that is converted to allicin by alliinase. Constituent of garlic (Alliumsativum).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252937	17795-26-5	C6H11NO3S	10 mg

• L-BMAA hydrochloride
  A neurotoxic amino acid originally isolated from Cycas circinalis, which may cause Guam disease, a form of amyotrophic lateral sclerosis.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252938	16012-55-8	C4H10N2O2•HCl	10 mg

• L-Kynurenine
  Key intermediate in the breakdown pathway of tryptophan.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202688	2922-83-0	C10H12N2O3	50 mg

• LED209 hydrate
  Sensor histidine kinase QseC is conserved in many bacterial pathogens. QseC upon presence of the bacterial aromatic signal autoinducer (AI-3) and/or host norepinephrine or epinephrine autophosphorylates and subsequently phosphorylates transcription factor QseB. These result in transcription of key virulence genes. LED209 antagonizes NE binding to QseC. It does not inhibits the pathogen growth but markedly inhibits virulence (for example Shiga toxin which is induced in EHEC by treatment with traditional antibiotics). LED209 does not interfere with mammalian adrenergic signaling, is orally bioavailable, and is non toxic to mice.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-252950	245342-14-7 (anhydrous)	C19H17N3O2S2•xH2O	5 mg

• lomerizine

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279282	101477-55-8	C27H30F2N2O3	1 g

• Meta Fluoxetine Hydrochloride
  A 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor derivative.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-211803	79088-29-2	C17H19ClF3NO	25 mg

• Methoprene acid
  Retinoic acid receptor (RXR) agonist used in gene regulation research. Analog of juvenile hormone, an insect growth hormone.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253007	53092-52-7	C16H28O3	5 mg

• MOCPAC
  Selective HDAC1 substrate (over HDAC6, class I over class II).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253051	787549-26-2	C27H31N3O6	2 mg

• Muscimol hydrobromide
  A potent but toxic structural analog of g-aminobutyric acid (GABA), with a zwitterionic structure that can cross the blood-brain barrier.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-218894	18174-72-6	C4H6N2O2•HBr	10 mg

• Myra A hydrochloride
  Myra A hydrochloride is a small molecule transcription factor inhibitor (c-Myc/Max DNA binding).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-301177	n.n.	C19H20N2O4•xHCl	5 mg

• N-(3X-Oxooctanoyl)-DL-homoserine lactone
  It is an autoinducer and potent antagonist. This stimulates the tra gene expression.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-257812	106983-27-1	C12H19NO4	25 mg

• N-(4-Amino-2-chlorophenyl)phthalimide
  An anticonvulsant.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253068	19348-53-9	C14H9ClN2O2	5 mg

• N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide
  A metabolite of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219275	n.n.	C20H29NO8	1 mg

• N,O-Didesmethyl-(rac-venlafaxine) Glucuronide Hydrochloride
  A metabolite of Venlafaxine which may at as a reuptake inhibitor of serotonin and noradrenaline.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208072	1021933-99-2	C21H32ClNO8	1 mg

• N2-Ethyl-2'-deoxyguanosine
  Adduct between DNA and acetaldehyde, the first metabolite of ethanol, that strongly blocks transcription by RNAPs (including RNAPII, both mammalian and yeast, E. coli RNAP, and T7 RNAP).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253167	101803-03-6	C12H17N5O4	5 mg

• Naphmethonium dibromide
  Very potent allosteric modulator of muscarinic receptors, selective for M2-receptors. Retards the dissociation of the antagonist N-methylscopolamine and exhibits positive cooperativity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202726	505059-27-8	C38H50Br2N4O4	5 mg

• NIDA-41020
  NIDA-41020 is a CB1 cannabinoid receptor antagonist. NIDA-41020 is structurally similar to Rimonabant, which is currently in clinical development. NIDA-41020 is less lipophilic; developed at NIDA as a potential radioligand for CB1 receptors, Ki = 4.1 nM [in comparison AM 251, AM 281, SR 141716 (Rimonabant) have Ki of 0.6, 4.5 and 1.8 nM respectively].

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253189	502486-89-7	C23H24Cl2N4O2	10 mg

• Norharmane hydrochloride
  Inhibitor of indoleamine 2,3-dioxygenase (IDO).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253201	7259-44-1	C11H8N2•HCl	100 mg

• NSC 295642
  A potent inhibitor of cell migration.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253204	77111-29-6	C30H28Cl2Cu2N6S4	5 mg

• NVP-231
  Ceramide kinase presents an attractive target for drug development because of its involvement in cell growth and inflammation. CerK biology is still poorly understood thus discovery and availability of inhibitors will facilitate research at this area. NVP-231 is a newly discovered potent, specific and reversible CerK inhibitor that competitively inhibits binding of ceraminde to CerK.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-255397	362003-83-6	C25H25N3O2S	5 mg

• OPC 4392 Hydrochloride
  An analogue of Aripiprazole, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219492	n.n.	C24H30ClN3O2	10 mg

• OU749
  Gamma-glutamyl transpeptidase (GGT; aka gamma-glutamyl transferase) cleaves the gamma-glutamyl bond of glutathione, making extracellular glutathione available for intracellular use. Elevated intracellular glutathione contributes to resistance of tumors to chemotherapy and radiation. GGT is a therapeutic target for treatment-resistance cancers, as treatment with GGT inhibitors prior to chemotherapy or radiation could sensitize GGT-positive tumors to treatment by decreasing glutathione levels. Previously, all GGT inhibitors have been glutamine analogues, which are competitive for the gamma-glutamyl site. Due to high toxicity, these compounds cannot be used in the clinic. OU749 is the first non-glutamine GGT inhibitor. It is also non-competitive for the gamma-glutamyl site. OU749 inhibits human GGT in an enzyme assay and is much less toxic than other GGT inhibitors, including azaserine (glutamine analogue, Sigma catalog).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253219	519170-13-9	C16H15N3O3S2	5 mg

• Oxiracetam
  Nootropic agent shown to exhibit learning and memory improvement and cognitive function impairment prevention. Mechanism of action has not been quantified, but current theories suggest a modulation of glutamatergic and cholinergic neurotransmissions with the possibility of PKC involvement.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-269996	62613-82-5	C6H10N2O3	10 mg

• Palmitoyl chloride

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-281122	112-67-4	C16H31ClO	100 ml/500 ml

• Pergolide Sulfone
  A metabolite of Pergolide, a dopaminergic agonist that also decrease plasma prolactin concentrations. An antiparkinsonian agent.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219576	n.n.	C19H26N2O2S	1 mg

• perospirone

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279959	150915-41-6	C23H30N4O2S	1 g

• Philanthotoxin 433 tris(trifluoroacetate) salt
  A polyamine-containing toxin that blocks NMDA-gated ion channels. Originally isolated from the venom of the wasp Philanthus triangulum.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-255421	276684-27-6	C23H41N5O3•3C2HF3O2	777 µg

• Phorbol
  A mammary tumor promoter used in experimental models.1

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253267	17673-25-5	C20H28O6	5 mg

• Phorbol 12,13-dinonanoate 20-homovanillate
  This product is a resiniferatoxin-type vanilloid phorbol ester that displays capsaicin-like selectivity for the vanilloid receptor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-301544	251362-87-5	C47H68O11	1 mg/5 mg

• PHPS1 sodium salt hydrate
  A phenylhydrazonopyrazolone sulfonate, which inhibits the phosphatase and cellular activities of Shp2.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253272	314291-83-3 (non-salt)	C21H14N5O6SNa ·xH2O	5 mg

• Physostigmine
  An alkaloid that acts as a potent and reversible inhibitor of cholinesterase. Forms an enzyme complex with aetylcholinesterase (AChE).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202764	57-47-6	C15H21N3O2	100 mg

• Phytoceramide C2
  This product has been shown to inhibit yeast growth, and to act as a ceramide-activated protein phosphatase (CAPP) activator.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-301547	n.n.	C20H41NO4	5 mg

• pikamilone sodium salt

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-279983	62936-56-5	C10H11NaN2O3	1 g

• PNU-74654
  Inhibits the Wnt-βcatenin pathway by blocking the interaction between β-catenin and TCF (T cell factor). Also an anti-tumor agent.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-258020	113906-27-7	C19H16N2O3	5 mg

• PP121
  PP121 has been shown to be anl inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-301605	1092788-83-4	C17H17N7	5 mg

• PP242 hydrate
  PP242 has been shown to be a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-301606	1092351-67-1 (anhydrous)	C16H16N6O•xH2O	5 mg/1 mg

• pramiracetam

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-280016	68497-62-1	C14H27N3O2	200 mg

• Psammaplin A
  An antibiotic, anti-tumor, DNA methyltransferase inhibitor. It is a bromotyrosine-derived, symmetrical conjugate of cystamine, which was first isolated from the Psammaplinaplysilla sponge. Impedes angiogenesis as well as bacterial and tumor cell growth. Inhibits the activities of several key enzymes in prokaryotic and eukaryotic systems including those involved in epigenetic control of gene expression, DNA replication, angiogensis, and microbial detoxification.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-258049	110659-91-1	C22H24Br2N4O6S2	1 mg/5 mg

• QBP1
  QBP1 is an inhibitor of polyglutamine protein aggregation and cell death. QBP1 inhibits polyglutamine aggregation in COS-7 cells at a concentration of 25 µM, as shown by complete inhibition of thioredoxin-Q62 aggregation assayed by turbidity at 405 nm. QBP1 reduces cell death of these cells by 50% and increases median life span from 5.5-52 days in Drosophilla melanogaster that expresses the expanded polyglutamine; can be shortened to 8 amino acids (Trp-Ley-Trp-Trp-Pro-Gly-Ile-Phe) without the loss of ability to inhibit polyglutamine aggregation. Several inherited neurodegenerative diseases, Huntington's dentatorubral pallidoluysian atrophy, spinobulbar muscular atrophy, and spinocerebellar ataxia are caused by the expanded CAG repeats in the coding region of the gene, leading to accumulation of polyglutamine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-301629	274914-75-9	C72H90N16O16•xC2HF3O2	1 mg

• quetiapine

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-280046	111974-69-7	C21H25N3O2S	2.5 mg

• R-Venlafaxine
  An isomer of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine with reported weak inhibitory effect on dopamine reuptake.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208209	93413-46-8	C17H27NO2	5 mg

• R-Venlafaxine-di-p-toluoyl-D-tartrate Salt
  A (-)-Venlafaxine derivative which may act as a reuptake inhibitor of serotonin and noradrenaline.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208210	272788-00-8	C37H45NO10	5 mg

• (R)-Fluoxetine Hydrochloride
  A 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208240	114247-09-5	C17H19ClF3NO	2.5 mg

• (R)-Fluoxetine-d5 Hydrochloride
  A deuterium-labeled 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219754	114247-09-5 (unlabeled)	C17H14D5ClF3NO	1 mg

• rac O-Desmethyl Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester
  A metabolic intermediate of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219870	n.n.	C29H41NO11	1 mg

• rac O-Desmethyl Venlafaxine β-D-Glucuronide
  A metabolite of the serotonin and noradrenalin reuptake inhibitor, Venlafaxine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208279	1021933-98-1	C22H33NO8	1 mg

• rac α-Methyl DOPA
  An antihypertensive agent.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219872	55-40-3	C10H13NO4	2.5 mg

• Retrorsine
  A pyrrolizidine alkaloid that contains antimitotic, cytotoxic, mutagenic properties. Retrorsine activation results after metabolism by cytochrome P450.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-215805	480-54-6	C18H25NO6	100 mg/500 mg

• Rizatriptan Benzoate
  A selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-219983	145202-66-0	C22H25N5O2	10 mg

• RM-65
  Compound is of interest to Broad researchers studying chromatin modifying compounds (e.g. BIX-01294). Cell (HepG2) permeable. Not selective between human and fungal PRMT, unlike AMI-1 (CLIC 2931). Paper tests diastereomeric mixture, yet models the R,R isomer. Compound does not hit lysine methyltransferase SET7/9.: Compound is of interest to Broad researchers studying chromatin modifying compounds (e.g. BIX-01294). Cell (HepG2) permeable.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-255522	947508-41-0	C34H32N2O4S2	5 mg

• S-(+)-O-Desmethyl Venlafaxine
  A metabolite of the neuroamine inhibitor Venlafaxine. May potentially inhibit reuptake of serotonin and norepinephrine with reported weak inhibitory effect on dopamine reuptake.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208319	142761-12-4	C16H25NO2	5 mg

• S-Venlafaxine
  An isomer of Venlafaxine, the reuptake inhibitor of neuroamines such as serotonin and norepinephrine with reported weak inhibitory effect on dopamine reuptake.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208330	93413-44-6	C17H27NO2	5 mg

• S-Venlafaxine-di-p-toluoyl-L-tartrate Salt
  A (+)-Venlafaxine derivative that may act as a serotonin and noradrenaline reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208331	272788-02-0	C37H45NO10	5 mg

• (S)-Citalopram Oxalate
  A derivative of Citalopram and a potential selective inhibitor of the 5-hydroxytryptamine transporter (serotonin).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208365	219861-08-2	C22H23FN2O5	10 mg/100 mg

• (S)-Fluoxetine Hydrochloride
  A 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-208367	114247-06-2	C17H19ClF3NO	2.5 mg

• (S)-Fluoxetine-d5 Hydrochloride
  A deuterium-labeled 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-220069	114247-06-2	C17H14D5ClF3NO	1 mg

• salicylsalicylic acid

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-281146	552-94-3	C14H10O5	25 g

• Sarcosine
  Endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204262	107-97-1	C3H7NO2	50 mg

• Sazetidine A dihydrochloride
  Novel ligand of nACh receptors. Potent agonist of native and recombinant α4β2 nACHRs.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203256	820231-95-6	C15H20N2O2 ·2HCl	1 mg

• tardan

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-280109	113-59-7	C18H18ClNS	5 mg

• Terodiline hydrochloride
  Terodiline hydrochloride is a non-selective calcium channel antagonist that has anticholinergic and vasodilatory activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253624	7082-21-5	C20H27N··HCl	5 mg

• Thapsigargicin
  Mobilizes intracellular Ca²⁺.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253692	67526-94-7	C32H46O12	1 mg

• TPBM
  An effective inhibitor of the alpha estrogen receptor via blockage of the ER-alpha dinging to consensus estrogen response element DNA. Displays minimal cellular toxicity and no effect on estrogen-independent cell growth.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-272620	6466-43-9	C15H16N4O2S	5 mg

• Tryptamine hydrochloride
  The prototypical indole of the Tryptamine family. Described to produce vasocontriction, potentially through the TAAR-1 receptor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202843	343-94-2	C10H12N2 ·HCl	5 g

• Vacuolin-1
  Alters the morphology of lysosomes, but not cell resealing.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-216045	351986-85-1	C26H24IN7O	1 mg

• Valpromide
  A derivative of Valproic acid (VPA) and is employed as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253822	2430-27-5	C8H17NO	10 mg

• Vanillic acid diethylamide
  A stimulant reactive to the CNS and respiratory.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253824	304-84-7	C12H17NO3	10 g

• Vecuronium Bromide
  A nonpolarizing neuromuscular relaxant.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-205880	50700-72-6	C34H57BrN2O4	10 mg/50 mg

• Venlafaxine Cyclic Impurity H
  An impurity of Venlafaxine, the neuroamine reuptake inhibitor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-213151	93413-70-8	C17H25NO2	1 mg

• Venlafaxine Hydrochloride
  A reuptake inhibitor of neurotransmitters such as serotonin and norepinephrine with reported weak inhibitory effect on dopamine reuptake.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201102	99300-78-4	C17H27NO2 ·HCl	10 mg/50 mg

• ω-Agatoxin IVA
  This toxin is found in the venom of the funnel web spider, Agelenopsis aptera. It is a potent, selective blocker of mammalian P-type voltage-dependent calcium channels.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-302015	145017-83-0	C217H360N68O60S10	100 µg

• Zonisamide sodium salt
  Zonisamide sodium salt is an anti-epileptic, that is effective in various animal epilepsy models and humans with both partial and generalized epileptic seizures. Zonisamide sodium salt scavenges nitric oxide (NO) as well.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253857	68291-98-5	C8H7N2NaO3S	10 mg