santa cruz biotechnology, inc.
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| | Leukotriene Receptor Ligands
- BAY-u 9773
A cysteinyl leukotriene receptor antagonist which displays equal affinity towards CysLT1 and CysLT2 receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203835 | 154978-38-8 | C27H36O5S | 50 µg |
- Cinalukast
Potent, selective leukotriene D4 receptor antagonist; orally active| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203893 | 128312-51-6 | C23H28N2O3S | 10 mg/50 mg |
- Dapsone
Leukotriene B4 (LTB4) antagonist. Inhibits LTB4 induced lysozyme release.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203023 | 80-08-0 | C12H12N2O2S | 1 g/5 g |
- FPL 55712
A LTD4, LTE4, LTF4, and LTC4 competitive antagonist. Shown to also be an SRS-A antagonist as well.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-203583 | 40786-08-1 | C27H30O9 | 10 mg |
- Leukotriene B4-dimethyl Amide
Leukotriene B4 antagonist. Antagonizes the degranulation response to LTB4 in rabbit PMNL acting, most likely, via receptor desensitization. Partial agonist at higher concentrations (5 µM).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-200702 | 83024-92-4 | C22H37NO3 | 50 µg |
- LY-255283
A hydroxyacetophenone that acts as a leukotriene B4 receptor antagonist which specifically binds to the BLT1 and BLT 2 receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-201346 | 117690-79-6 | C19H28N4O3 | 1 mg/5 mg |
- MK-571
Shown to be a leukotriene receptor ligand which specifically inhibits LTD4 binding to CysLT1 receptors. Also reported as an anti-inflammatory agent. | Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-201340 | 115104-28-4 | C26H26ClN2O3S2··Na | 5 mg/25 mg |
- ONO 1078
CysLT1 antagonist. Downplays contraction of smooth airway muscle, microvascular leakage into airways and eosinophil infiltration. Potential to decrease symptoms of bronchial asthma.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-204148 | 103177-37-3 | C27H23N5O4 | 50 mg |
- REV-5901
A dual activity leukotriene D4 antagonist (Ki=0.7 µM, inhibition of [3H]-LTD4 binding to guinea pig lung membranes)1 and 5-lipoxygenase inhibitor (IC50=6 µM).| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-205488 | 101910-24-1 | C22H25NO2 | 10 mg/50 mg |
- SR 2640 Hydrochloride
Potent and selective competitive leukotriene D4 and E4 receptor antagonist. Inhibits LTD4- but not histamine-induced guinea pig ileum and trachea contraction (pA2 = 8.7). Also inhibits LTD4-attenuation of human PMN chemotaxis. Orally active in vivo.
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| sc-204902 | 105350-26-3 | C23H18N2O3 ·HCl | 10 mg/50 mg |
- U-75302
Selective leukotriene B4 antagonist, Ki=159 nM for inhibition of [3H]-LTB4 binding to guinea pig lung membranes.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-201331 | 119477-85-9 | C22H35NO3 | 100 µg |
- Verlukast
A receptor antagonist for the treatment of respiratory diseases.| Katalog # | CAS Nummer | Summenformel | Menge |
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| sc-213152 | 120443-16-5 | C26H27ClN2O3S2 | 5 mg |
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