Hydroperoxy-Acids, DiHETEs, HETEs and Other Hydroxy-Acids

• (±)5-HETrE
  An essential fatty acid analogue of arachidonic acid that is readily converted to leukotriene A3 via the 5-lipoxygenase-leukotriene pathway.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200948	88053-46-7	C20H34O3	50 µg

• (±) 5-HETE Lactone
  A unique marker for 5-lipoxygenase activation.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200957	73279-37-5	C20H30O2	50 µg/1 mg

• 5(S)-HETE
  5-HETE is a product of the arachidonic acid metabolism lioxygenase pathway. It is chemotactic and chemokinetic for human neutrophils.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200939	70608-72-9	C20H32O3	50 µg

• 5(S),6(R)-DiHETE
  An enzymatic metabolite of leukotriene A4 that functions as a LTD4 (sc-201048) receptor agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200421	82948-88-7	C20H32O4	50 µg/1 mg

• 5(S)-HPETE
  A monohydroperoxy polyunsaturated fatty acid produced by 5-LO metabolism of arachidonic acid. A biosynthetic precursor to leukotrienes. Demonstrated to modulate histamine release in basophils and to induce c-fos in TA1 cells.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200962	71774-08-8	C20H32O4	50 µg/1 mg

• 5(S),12(S)-DiHETE (6-trans-12-epi-LTB4)
  Biosynthesis via nonenzymatic hydrolysis of LTA4 and by myeloperoxidase-dependent metabolism of cysteinyl leukotrienes.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200426	73151-67-4	C20H32O4	50 µg/1 mg

• 5(S),15(S)-DiHETE
  5(S),15(S)-DiHETE is biosynthesised in human eosinophils. It has shown to enhance neutrophil degranulation and serve as a potent chemotaxin for human eosinophils.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200413	82200-87-1	C20H32O4	50 µg/1 mg

• 8(S)-HETE
  A polyunsaturated fatty acid chemotactic for neutrophils and an intermediate in the synthesis of the family of eicosanoids known as leukotrienes shown to regulate epithelial cell migration during wound healing.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200940	98462-03-4	C20H32O3	50 µg

• 8(R),15(S)-DiHETE
  Produces a dose-dependent hyperalgesia. Stereospecifically sensitizes C-fiber mechanoheat nociceptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200425	80234-67-9	C20H32O4	50 µg

• 8(S),15(S)-DiHETE (Z, E, Z, E)
  A novel dioxygenation product of arachidonic acid which possesses chemotactic activity for human polymorphonuclear leukocytes (PMNLs) comparable to that of leukotriene B4.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200415	80234-65-7	C20H32O4	50 µg/1 mg

• 8(S),15(S)-DiHETE (Z, E, E, E)
  Antagonizes hyperalgesic effects produced by 8(R),15(S)-DiHETE.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200428	80234-66-8	C20H32O4	50 µg

• (+/-)-9-HETE
  Metabolism of free radical-mediated arachidonic acid oxidation forms 9-HETE.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200941	79495-85-5	C20H32O3	50 µg

• 12(S)-HETE
  An arachidonic acid metabolite synthesized in the 12-lipoxygenase pathway in platelets and macrophages.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200942	54397-83-0	C20H32O3	50 µg/1 mg

• 12(R)-HETE
  An arachidonic acid metabolite synthesized in the 12-lipoxygenase pathway in platelets and macrophages.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200946	82337-46-0	C20H32O3	50 µg/1 mg

• 12(S)-HHT
  This product is know to inhibit human platelet aggregation. It has been shown to stimulate the production of prostacyclin.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200969	54397-84-1	C17H28O3	50 µg/1 mg

• 12(S),20-DiHETE
  An Arachidonic acid metabolite that activates cytoplasmic and lysosomal cholesteryl ester hydrolytic activity

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200412	89614-44-8	C20H32O4	50 µg

• 15(S)-HETE
  15(S)-HETE is an arachidonic acid metabolite with immunosuppressive, stimulation of endothelial cellmigration and neovascularization and anti tumor activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200944	54845-95-3	C20H32O3	50 µg/1 mg

• 15(S)-HETrE
  Biosynthesis from dihomo-γ-linolenic acid in human platelets and mouse peritoneal macrophages. Anti-inflammatory, inhibits 5-LO and 12-LO.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200949	13222-49-6	C20H34O3	50 µg/1 mg

• 15(S)-HEPE
  This is a polyunsaturated fatty acid, that is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200951	86282-92-0	C20H30O3	50 µg

• 15(S)-HPETE
  This inhibits prostacyclin synthase and arachidonic acid induced platelet aggregation.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200966	70981-96-3	C20H32O4	50 µg/1 mg

• 15(S)- HPEPE
  Primary metabolite of eicosapentaenoic acid via the 15-lipoxygenase pathway. It is expected to behave similarly to 15(S)-HpETE (catalog number sc-200966 and sc-200966A).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-200968	125992-60-1	C20H30O4	50 µg