santa cruz biotechnology, inc.
SCBT Logo

Willkommen!        Produkt(e) im Warenkorb.     Bestellen
Home » Chemikalien » Histaminergics
 

Histaminergics

  • 2-Pyridylethylamine dihydrochloride
    Histamine H1 receptor agonist that produces vasoconstriction in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-2034673343-39-3C7H10N2•2HCl50 mg
  • 4-Methylhistamine dihydrochloride
    Potent, high affinity H4 receptor agonist (Ki = 7 nM) that displays > 100-fold selectivity as compared to other human histamine receptor subtypes.
    Katalog #CAS NummerSummenformelMenge
    sc-20347536376-47-3C6H11N3.2HCl10 mg/50 mg
  • (+)-α-Methylhistamine dihydrobromide
    Less active enantiomer of H3 agonist R-(-)-α-methylhistamine. 120-fold less potent than R-(-) at H3.
    Katalog #CAS NummerSummenformelMenge
    sc-20442675614-93-6C6H11N3•2HBr10 mg/50 mg
  • A 987306
    A potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo (ED50 = 42 μmol/kg, ip).
    Katalog #CAS NummerSummenformelMenge
    sc-2917761082954-71-9C18H25N5O10 mg/50 mg
  • Aminopotentidine
    A very potent and specific histamine H2-receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203817140873-26-3C26H35N7O210 mg
  • Amthamine
    Amthamine is a highly selective histamine H2 agonist, devoid of stimulatory activity at H1 and H3 receptors
    Katalog #CAS NummerSummenformelMenge
    sc-201087142437-67-0C6H11N3S5 mg
  • Amthamine dihydrobromide
    Amthamine dihydrobromide is a H2 histamine receptor agonist. This is similar to histamine, which inhibits H2 receptor-mediated eosinophil peroxidase (EPO) release with IC50 = 0.4 µM; a weak antagonist at H3 and shows no activity at H1 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-239248142457-00-9C6H11N3S•2HBr10 mg
  • Antazoline hydrochloride
    Imidazoline binding site ligand; a potent inducer of insulin secretion in rat pancreas and also an antihistamine.
    Katalog #CAS NummerSummenformelMenge
    sc-2035152508-72-7C17H19N3 ·HCl100 mg
  • Astemizole
    A potent antihistamine (H1-receptor antagonist) that displays selectivity for H1 receptors over 5-HT, dopamine and muscarinic acetylcholine receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20108868844-77-9C28H31FN4O10 mg/50 mg
  • Azelastine HCl
    An H1-receptor antagonist with associated antiallergic activity. Also shown to block the secretion of IL-6, IL-8, and TNF-α from mast cells.
    Katalog #CAS NummerSummenformelMenge
    sc-20109679307-93-0C22H24ClN3O ·HCl100 mg
  • Buclizine, Dihydrochloride
    An antihistamine used as an anti-emetic.
    Katalog #CAS NummerSummenformelMenge
    sc-210969129-74-8C28H37Cl3N250 mg
  • Brompheniramine Maleate
    Antihistaminic.
    Katalog #CAS NummerSummenformelMenge
    sc-210967980-71-2C16H19BrN2 ·C4H4O425 mg/250 mg
  • Burimamide oxalate
    Mixed H2/H3 antagonist. IN SK-N-MC cells, displays partial agonist activity. Following intraventricular administration, produces antinociceptive effects.
    Katalog #CAS NummerSummenformelMenge
    sc-20353534970-69-9C9H16N4S•C2H2O410 mg/50 mg
  • Chlorpheniramine Maleate
    An antagonist of the histamine H1-receptor. Blocks the induction of ornithine decarboxylase activity by histamine in multiple systems.
    Katalog #CAS NummerSummenformelMenge
    sc-204684113-92-8C16H19ClN2 ·C4H4O45 g/25 g
  • Cetirizine Dihydrochloride
    Histamine H1 receptor antagonist that displays selectivity over other receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20299283881-52-1C21H25ClN2O3 ·2HCl50 mg
  • Cimetidine
    Immunomodulator. Suppresses the growth of several tumors, including gastrointestinal cancer.An anti-angiogenic agent.
    Katalog #CAS NummerSummenformelMenge
    sc-20299651481-61-9C10H16N6S5 g/10 g
  • Clemastine fumarate
    Selective histamine H1 antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20389714976-57-9C21H26ClNO ·C4H4O4100 mg
  • Clobenpropit Dihydrobromide, VUF 9153
    Shown to be a histamine H3 receptor antagonist through increase of brain histidine decarboxylase activity. Has also been reported to modulate neurotransmitter release.
    Katalog #CAS NummerSummenformelMenge
    sc-202999145231-45-4C14H17ClN4S ·2HBr10 mg/50 mg
  • Clobenpropit hydrobromide
    A selective histamine H3 receptor antagonist that crosses the blood-brain barrier, inhibiting histamine binding in rat brain. Exhibits protection of cultured cortical neurons from NMDA-induced excitotoxicity by stimulating GABA release and in mice and rats, protects against kindled seizures through its effects on histamine and GABA.
    Katalog #CAS NummerSummenformelMenge
    sc-205258145231-35-2C14H17ClN4S ·2HBr1 mg/10 mg
  • Conessine
    Selective and potent histamine H3 receptor antagonist (pKi values are 7.61 and 8.27 at rat and human H3 receptors respectively). A steroidal alkaloid which displays in vitro antiplasmodial activity (IC50 = 1.04 μM). High affinity for α2C adrenoceptors (pKi = 7.98).
    Katalog #CAS NummerSummenformelMenge
    sc-203554546-06-5C24H40N250 mg
  • Dimaprit·2HCl
    Selective histamine H2 agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20109023256-33-9C6H15N3S•2HCl100 mg
  • Dimebolin dihydrochloride
    Dimebolin (hydrochloride), also known as Dimebon™, is an orally-available drug, approved in Russia for use as a non-selective antihistamine, that has shown promise in the treatment of neurodegenerative diseases, including Alzheimer’s disease and Huntington’s disease. In addition to preventing the onset and progression of disease by being neuroprotective, Dimebolin appears to promote clinical improvement by increasing cognitive function. At the cellular level, Dimebolin appears to have diverse effects, inhibiting the neurotoxic action of β-amyloid and blocking L-type calcium channels, inhibiting NMDA-type glutamate receptors, and preventing mitochondrial leakage.,6,7 The hydrochloride form of Dimebolin is soluble in both aqueous and organic solvents.
    Katalog #CAS NummerSummenformelMenge
    sc-29434897657-92-6C21H25N3•2HCl1 mg/5 mg/50 mg
  • DPPE Fumarate
    Has high affinity for the anti-estrogen binding site. Inhibits histamine binding at the intracellular histamine (Hlc) site. Does not bind to the estrogen receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-205942n.n.C19H25NO ·C4H4O410 mg/50 mg
  • Doxepin hydrochloride
    Highly potent histamine H1 antagonist. Also binds to H4 receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-2039301229-29-4C19H21NO•HCl1 g
  • Ebastine
    A non-sedating histamine H1 receptor antagonist that inhibits T cell migration as well and may find a use in the treatment of Th2-type autoimmune diseases.
    Katalog #CAS NummerSummenformelMenge
    sc-20566390729-43-4C32H39NO21 g/5 g
  • Fexofenadine HCl
    Shown to be a nonsedating histamine H1 receptor agonist that is a metabolite of terfenadine. Also reported as an inhibitor of Cox-1 and Cox-2 activity.
    Katalog #CAS NummerSummenformelMenge
    sc-203047153439-40-8C32H39NO4 ·HCl10 mg/50 mg
  • Histamine dihydrochloride
    A potent vasodilator that acts as an agonist for endogenous histamine receptors, H1 and H2.
    Katalog #CAS NummerSummenformelMenge
    sc-20265056-92-8C5H9N3 ·2HCl5 g
  • HTMT dimaleate
    Mixed H1/H2 histamine agonist; significantly more potent than histamine itself.
    Katalog #CAS NummerSummenformelMenge
    sc-204003195867-54-0C19H25F3N4O•2C4H4O410 mg/50 mg
  • Hydroxyzine Dihydrochloride
    Anxiolytic, antihistaminic piperazine compound. It is a hetercyclic H1 receptor antagonist that is also known to block mast cells.
    Katalog #CAS NummerSummenformelMenge
    sc-2057162192-20-3C21H27ClN2O2•2HCl5 g/10 g
  • ICI 162,846
    Katalog #CAS NummerSummenformelMenge
    sc-36120784545-30-2C11H17F3N6O50 mg
  • Imetit dihydrobromide
    Effective, high affinity H3 and H4 agonist with KI values of 0.3 and 2.7 nM. Triggers eosinophil shape change with EC50 of 25 nM. Centrally active after systemic administration.
    Katalog #CAS NummerSummenformelMenge
    sc-20360232385-58-3C6H10N4S•2HBr10 mg
  • Immethridine dihydrobromide
    Strong and highly selective histamine H3 receptor agonist (pEC50 = 9.74) that displays 300-fold selectivity over the H4 receptor (pKi values are 9.07 and 6.61 respectively). Does not bind to H1 or H2 receptors at concentrations up to 10 μM.
    Katalog #CAS NummerSummenformelMenge
    sc-20360387976-03-2C9H9N3•2HBr10 mg/50 mg
  • Immepip dihydrobromide
    Standard histamine agonist. Selective for H3 and H4. Equipotent or slightly more active on H3 receptors than sc-201091.
    Katalog #CAS NummerSummenformelMenge
    sc-204010164391-47-3C9H15N3•2HBr10 mg/50 mg
  • Impentamine dihydrobromide
    Selective H3 receptor antagonist. Displays >30000-fold selectivity over H1 and H2 receptors. In SK-N-MC cells expressing human H3 receptors, this can act as a partial agonist. Following central in vivo administration, produces antnociception, possibly through a non-H1, -H2, or -H3 receptor-mediated mechanism.
    Katalog #CAS NummerSummenformelMenge
    sc-20360434973-91-6C8H15N3•2HBr10 mg/50 mg
  • Iodophenpropit dihydrobromide
    Katalog #CAS NummerSummenformelMenge
    sc-361213143407-29-8C15H19IN4S.2HBr10 mg/50 mg
  • JNJ 10191584 maleate
    Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM) and is > 540-fold selective over the H3 receptor (Ki = 14.1 μM). In vitro, inhibits mast cell and eosinophil chemotaxis with IC50 values of 138 and 530 nM respectively. Orally active in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-203613869497-75-6C13H15ClN4O C4H4O410 mg/50 mg
  • Ketotifen fumarate
    A histamine H1 antagonist and inhibitor of mast cell growth. Also an inhibitor of vascular permeability and conjuctival edema.
    Katalog #CAS NummerSummenformelMenge
    sc-20109434580-14-8C19H19NOS ·C4H4O41 g
  • L-Histidinol dihydrochloride
    A precursor of histamine and a reversible inhibitor of protein synthesis.
    Katalog #CAS NummerSummenformelMenge
    sc-2078011596-64-1C6H11N3O•2HCl1 g
  • Levocabastine HCl
    Histamine H1 receptor antagonist. Anti-allergic agent. An antagonist of low affinity neurotensin receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20109579547-78-7C26H29FN2O2•HCl10 mg
  • Loratadine
    A non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.
    Katalog #CAS NummerSummenformelMenge
    sc-20311779794-75-5C22H23ClN2O210 mg/50 mg
  • Mepyramine maleate
    Selective inverse agonist for the H1 receptor. Inhibits histamine induced inositol phosphate (InsP) production (log EC50 = -7.94) and intracellular calcium mobilization. Sequesters Gq/11 protein, reducing its availability for other receptors associated with the same signaling pathway.
    Katalog #CAS NummerSummenformelMenge
    sc-20362959-33-6C21H27N3O5100 mg
  • Methimepip dihydrobromide
    Extremely selective histamine H3 receptor agonist (pKi values are 9.0, 5.7, < 5.0 and < 5.0 for hH3, hH4, hH1 and hH2 receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD2 = 8.26).
    Katalog #CAS NummerSummenformelMenge
    sc-204080151070-80-3C10H17N3.2HBr10 mg/50 mg
  • R(-)-α-Methylhistamine·2HBr
    A selective agonist of the histamine H3-receptor with one order of magnitude higher affinity than histamine itself. Agonism of the H3-receptor attenuates histamine secretion and release from histaminergic neurons.
    Katalog #CAS NummerSummenformelMenge
    sc-20109175614-87-8C6H11N3 ·2HBr10 mg
  • N-Methyl-1H-imidazole-4-ethanamine dihydrochloride
    Potent histamine agonist, especially at H3 receptors (potency relative to histamine is 81, 185, and 270% at H1, H2 and H3 respectively). Displays agonist properties at H4 receptors to which it binds with moderate affinity (Ki = 23 nM).
    Katalog #CAS NummerSummenformelMenge
    sc-203638673-50-7C6H11N3 ·2HCl10 mg/50 mg
  • Nizatidine
    An H2-receptor antagonist. A potent inhibitor of gastric acid secretion.
    Katalog #CAS NummerSummenformelMenge
    sc-20577176963-41-2C12H21N5O2S25 g/10 g
  • Orphenadrine Citrate Salt
    Used as a skeletal muscle relaxant which exhibits antihistaminic properties.
    Katalog #CAS NummerSummenformelMenge
    sc-2124814682-36-4C18H23NO ·C6H8O75 g
  • Proxyfan oxalate
    High affinity histamine H3 receptor ligand that acts as a protean (shape changing) agonist at recombinant and native receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204867177708-09-7C13H16N2O.C4H4O410 mg/50 mg
  • Ranitidine
    A non-imidazole blocker of histamine receptors which mediate gastric secretion (H2 receptors). Used to treat gastrointestinal ulcers.
    Katalog #CAS NummerSummenformelMenge
    sc-20367966357-35-5C13H22N4O3S1 g
  • Ranitidine hydrochloride
    A histamine H2-receptor antagonist used in the treatment of gastrointestinal lesions due to excessive gastric acid secretion.
    Katalog #CAS NummerSummenformelMenge
    sc-20487466357-59-3C13H22N4O3S ·HCl1 g
  • ROS 234 dioxalate
    Potent H3 antagonist. Limited blood brain barrier permeability.
    Katalog #CAS NummerSummenformelMenge
    sc-204893184576-87-2C17H19N5O810 mg/50 mg
  • Roxatidine Acetate Hydrochloride
    A histamine H2-receptor antagonist used in ulcer treatment. This compound has been found to inhibit platelet function in vitro.
    Katalog #CAS NummerSummenformelMenge
    sc-20584493793-83-0C19H28N2O4 ·HCl100 mg/500 mg
  • S15535
    A potent, orally active, partial 5-HT1A receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-250959146998-34-7C21H24N2O25 mg
  • Thioperamide·maleate
    A selective histamine H3 receptor antagonist shown to cross the blood-brain barrier, that binds to rat cerebral cortical cells in vitro, and inhibits histamine binding in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-201092106243-16-7C15H24N4S ·C4H4O410 mg/50 mg
  • Tiotidine
    Katalog #CAS NummerSummenformelMenge
    sc-36138269014-14-8C10H16N8S210 mg/50 mg
  • trans-Triprolidine hydrochloride
    Potent H1 receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-2043546138-79-0C19H22N2•HCl100 mg
  • VUF 5681 dihydrobromide
    Potent histamine H3 receptor silent antagonist (pKi = 8.35).
    Katalog #CAS NummerSummenformelMenge
    sc-204389639089-06-8C11H19N3 ·2HBr10 mg/50 mg
  • VUF 8430 dihydrobromide
    A potent histamine H4 receptor full agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20371998021-17-1C4H11N5S ·2HBr ·14 ·H2O10 mg/50 mg
  • Zolantidine dimaleate
    Katalog #CAS NummerSummenformelMenge
    sc-361422104076-38-2C22H27N3OS.2C4H4O410 mg/50 mg