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Glutamatergics

  • (±)-1-(1,2-Diphenylethyl)piperidine maleate
    NMDA receptor ion channel blocker.
    Katalog #CAS NummerSummenformelMenge
    sc-20373236794-52-2C19H23N ·C4H4O410 mg/50 mg
  • 1-Aminocyclobutane-cis-1,3-dicarboxylic acid
    A very potent, competitive and selective inhibitor of glutamate uptake.
    Katalog #CAS NummerSummenformelMenge
    sc-200438117488-23-0C6H9NO45 mg/25 mg
  • 1-Aminocyclobutane-trans-1,3-dicarboxylic acid
    A very potent, competitive and selective inhibitor of glutamate uptake.
    Katalog #CAS NummerSummenformelMenge
    sc-36107273550-55-7C6H9NO410 mg/50 mg
  • 1-Aminocyclopentanecarboxylic acid
    NMDA receptor antagonist acting at the glycine site.
    Katalog #CAS NummerSummenformelMenge
    sc-20239252-52-8C6H11NO210 mg
  • 1-Aminocyclopropane-1-carboxylic Acid
    An agonist at the glycine modulatory site of the NMDA receptor. Mimics the effects of glycine on the NMDAR and competitively inhibits glycine-NMDAR binding.
    Katalog #CAS NummerSummenformelMenge
    sc-20239322059-21-8C4H7NO2500 mg
  • 1-BCP
    Centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.
    Katalog #CAS NummerSummenformelMenge
    sc-20345434023-62-6C13H15NO310 mg/50 mg
  • 1-Benzyl-APDC hydrochloride
    A selective ligand of mGlu6 receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-220463n.n.C13H16N2O4•HCl1 mg/5 mg
  • (1R,3R)-homo-ACPD
    Katalog #CAS NummerSummenformelMenge
    sc-206296n.n.C8H13NO45 mg
  • (1R,3S)-homo-ACPD
    Inactive isomer of trans-1,3-homo-ACPD.
    Katalog #CAS NummerSummenformelMenge
    sc-206299n.n.C8H13NO45 mg
  • (1S,3R)-ACPD
    A rigid analog of glutamate. Excites metabotropic receptors with α-kainic acid-like action.
    Katalog #CAS NummerSummenformelMenge
    sc-202009111900-32-4C7H11NO45 mg/25 mg
  • (1S,3R)-homo-ACPD
    Active isomer of trans-1,2-homo-ACPD. Highly selective agonist for group II mGluRs and has no effect at ionotropic excitatory amino acid receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-205919n.n.C8H13NO45 mg
  • (1S,3S)-homo-ACPD
    Isomer of cis-1,3-homo-ACPD. Partial agonist for group II mGluRs. Displays no effect at ionotropic excitatory amino acid receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-206307n.n.C8H13NO45 mg
  • (-/+)-2-amino-7-phosphonoheptanoic acid
    This product is a NMDA antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-28780685797-13-3C7H16NO5P2 mg/5 mg
  • 2,4-Dihydroxyphenylacetyl-L-asparagine
    Component of various spider toxins and purported specific blocker of glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203468111872-98-1C12H14N2O610 mg/50 mg
  • (2R,3S)-Chlorpheg
    A weakly active NMDA receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203775n.n.C11H12ClNO410 mg
  • (2R,4R)-(+)-Azetidine-2,4-dicarboxylic acid
    A selective pharmacological agent of the metabotropic glutamate (mGlu) receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-205922161596-63-0C5H7NO41 mg
  • (2R,4R)-APDC
    A highly selective agonist for group II metabotropic glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-202408169209-63-6C6H10N2O41 mg/5 mg
  • (2S,3S,4S)-2-Methyl-2-(carboxycyclopropyl)glycine
    Selective group II mGluR antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-202014157141-16-7C7H11NO41 mg/5 mg
  • (2S,4R)-4-Methylglutamic Acid
    A highly selective and potent agonist for kainate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-21633831137-74-3C6H11NO45 mg
  • (2S,4S)-(-)-Azetidine-2,4-dicarboxylic acid
    Katalog #CAS NummerSummenformelMenge
    sc-220844161596-62-9C5H7NO41 mg
  • (2S)-2-Hydroxyglutaric Acid
    Potential inhibitor of glutamate carboxypeptidase.
    Katalog #CAS NummerSummenformelMenge
    sc-31169613095-48-2C5H8O525 mg
  • (2S)-α-Ethylglutamic acid
    Group II mGluR antagonist
    Katalog #CAS NummerSummenformelMenge
    sc-220848n.n.C7H13NO41 mg
  • (+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid
    Displays NMDA antagonistic activity.
    Katalog #CAS NummerSummenformelMenge
    sc-288641100828-16-8C8H17N2O5P10 mg
  • 3-MATIDA
    Potent metabotropic glutamate mGlu1 receptor antagonist (IC50 = 6.3 μM at rat mGlu1a).
    Katalog #CAS NummerSummenformelMenge
    sc-203470518357-51-2C8H9NO4S•xH2010 mg/50 mg
  • 5,7-Dichlorokynurenic acid
    A potent antagonist at the NMDA receptor glycine modulatory site. Noncompetitively antagonizes NMDA-stimulated responses.
    Katalog #CAS NummerSummenformelMenge
    sc-200440131123-76-7C10H5Cl2NO310 mg/50 mg
  • 5,7-Dichlorokynurenic acid sodium salt
    A sodium salt of 5,7-Dichlorokynurenic acid (sc-200440). Acts as a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine).
    Katalog #CAS NummerSummenformelMenge
    sc-291018131123-76-7 (non-salt)C10H4Cl2NNaO310 mg/50 mg
  • 6,7-Dinitroquinoxaline-2,3-dione (DNQX)
    A non-NMDA receptor complex antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-2004442379-57-9C8H4N4O610 mg/50 mg
  • 7-Chlorokynurenic acid
    NMDA receptor antagonist acting at the glycine site.
    Katalog #CAS NummerSummenformelMenge
    sc-35871718000-24-3C10H6CINO310 mg/50 mg
  • 7-Chlorokynurenic acid sodium salt
    Sodium salt of 7-Chlorokynurenic acid (sc-202893), an NMDA receptor antagonist acting at the glycine site. Acts as a potent competitive inhibitor of L-glutamate transport into synaptic vesicles.
    Katalog #CAS NummerSummenformelMenge
    sc-291578n.n.C10H5CINNaO310 mg/50 mg
  • 7-Chlorothiokynurenic acid hydrochloride
    NMDA receptor antagonist acting at the glycine site. More potent than the corresponding kynurenic acid analog.
    Katalog #CAS NummerSummenformelMenge
    sc-202430135025-56-8C10H6ClNO2S ·HCl5 mg
  • A 841720
    Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analgesic effects; decreases mechanical allodynia in models of neuropathic pain;impairs cognitive function
    Katalog #CAS NummerSummenformelMenge
    sc-203792869802-58-4C17H21N5OS10 mg/50 mg
  • ACBC
    NMDA receptor antagonist acting at the glycine site.
    Katalog #CAS NummerSummenformelMenge
    sc-20349322264-50-2C5H9NO225 mg
  • ACDPP hydrochloride
    Antagonist at the mGlu5 receptor (Ki = 295 nM). Inhibits human mGlu5 receptor-mediated calcium flux with an IC50 of 134 nM.
    Katalog #CAS NummerSummenformelMenge
    sc-20349437804-11-8C12H13ClN6O•HCl•xH2010 mg/50 mg
  • ACET
    Potent and selective GluR5-containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA recptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.
    Katalog #CAS NummerSummenformelMenge
    sc-203801n.n.C20H19N3O6S10 mg
  • AIDA
    A selective antagonist of the mGluR1. Competitively antagonizes the stimulatory response of glutamate at mGluR1a.
    Katalog #CAS NummerSummenformelMenge
    sc-202047168560-79-0C11H11NO45 mg
  • (+/-)-alpha-Amino-3-hydroxy-5-methylisoxazole- 4-propionic Acid Hydrobromide
    Shows highly potent agonist activity towards central glutamate/quisqualate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-291862118896-96-1C7H10N2O4 ·HBr1 mg/5 mg
  • α-Benzylquisqualic acid
    Selective antagonist of group II mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-221178n.n.C12H13N3O51 mg/5 mg
  • α-Ketoglutaric acid sodium salt
    Katalog #CAS NummerSummenformelMenge
    sc-21444922202-68-2C5H5NaO51 g/5 g
  • AMN082 Dihydrochloride
    Potent and selective agonist at mGluR7 acting at an allosteric site.
    Katalog #CAS NummerSummenformelMenge
    sc-20048383027-13-8C28H28N2 ·2HCl10 mg/50 mg
  • AMPA
    A potent agonist of the AMPA receptor, a glutamate-recognizing ionotropic receptor. Agonism of the AMPA receptor produces neuronal excitation.
    Katalog #CAS NummerSummenformelMenge
    sc-20043774341-63-2C7H10N2O45 mg/50 mg
  • Aniracetam
    Nootropic with modulatory actions through allosteric potentiation of reduction of glutamate receptor desensitization, AMPA specific receptors, and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration.
    Katalog #CAS NummerSummenformelMenge
    sc-20351472432-10-1C12H13NO350 mg/250 mg
  • Arcaine sulfate
    Arcaine is a novel and potent antagonist of the polyamine site on the NMDA receptor. it can inhibit [3H]MK801 binding in the absence of added polyamines.
    Katalog #CAS NummerSummenformelMenge
    sc-20047514923-17-2C6H16N6 ·H2SO420 mg/50 mg
  • BINA
    Katalog #CAS NummerSummenformelMenge
    sc-361121866823-73-6C30H30O410 mg/50 mg
  • Boc-L-Glutamic acid 5-fluorenyl methyl ester
    Katalog #CAS NummerSummenformelMenge
    sc-285175123417-18-5C24H27NO61 g/5 g
  • CBiPES hydrochloride
    Positive allosteric modulator of the mGlu2 receptor
    Katalog #CAS NummerSummenformelMenge
    sc-358830856702-40-4C21H19N3O2S•HCl10 mg/50 mg
  • CCMQ
    Acts selectively when inhibiting homoquinolinic acid binding to non-NMDA sensitive sites. Works in combination with [3H]-homoquinolinic acid to characterize NR2B-containing NMDA receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-205625n.n.C12H9NO410 mg/50 mg
  • CFM-2
    A novel, selective, non-competitive AMPA antagonist1.
    Katalog #CAS NummerSummenformelMenge
    sc-203429178616-26-7C17H17N3O310 mg
  • CGP 37849
    Potent, competitive and selective NMDA antagonist. Orally active anticonvulsive.
    Katalog #CAS NummerSummenformelMenge
    sc-203880127910-31-0C6H12NO5P10 mg/50 mg
  • CGP 39551
    Katalog #CAS NummerSummenformelMenge
    sc-361139127910-32-1C8H16NO5P10 mg/50 mg
  • CGP 78608 hydrochloride
    Katalog #CAS NummerSummenformelMenge
    sc-361144206648-13-7C11H13BrN3O5P.HCl10 mg/50 mg
  • CGS 19755
    Potent, competitive NMDA antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203882110347-85-8C7H14NO5P10 mg/50 mg
  • Chicago Sky Blue 6B
    Katalog #CAS NummerSummenformelMenge
    sc-3611462610-05-1C34H24N6Na4O16S425 g
  • CHPG
    A selective metabotropic glutamate receptor agonist, mGlu5. Inactive at mGlu1a receptors which are expressed in CHO cells. Active in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-205931170846-74-9C8H8NO3Cl10 mg/50 mg
  • CHPG Sodium salt
    Katalog #CAS NummerSummenformelMenge
    sc-361148n.n.C8H7ClNO3 ·Na10 mg/50 mg
  • cis-(+/-)-3,4-Dichloro-N-Methyl-N-(2-[1-Pyrrolidinyl]Cyclo- Hexyl)Benzeneacetamide Hydrochloride
    Shown to be a potent antagonist of NMDA and displays anticonvulsant effects.
    Katalog #CAS NummerSummenformelMenge
    sc-29403692953-41-8C18H24Cl2N2O1 mg/5 mg
  • cis-1,3-homo-ACPD
    An equimolar mixture of (1R,3R)-homo-ACPD and (1S,3S)-homo-ACPD. This compound is a selective agonist for group II mGluRs and has no effect at ionotropic excitatory amino acid receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-205932n.n.C8H13NO45 mg
  • cis-ACPD
    Potent NMDA agonist. Equimolar mixture of (1R,3R)-ACPD
    Katalog #CAS NummerSummenformelMenge
    sc-20210239026-63-6C7H11NO45 mg
  • Cl-HIBO
    Highly desensitising AMPA receptor agonist. Subtype selective for GluR1 and GluR2 subunit-containing receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-205934n.n.C6H7ClN2O410 mg/50 mg
  • CNQX disodium salt
    Water soluble, potent competitive kainate/quisqualate (non-NMDA) receptor antagonist. More soluble form of CNQX
    Katalog #CAS NummerSummenformelMenge
    sc-203003115066-14-3 (non-salt)C9H2N4O4Na25 mg/10 mg
  • Co 101244 hydrochloride
    Highly selective N-methyl-D-aspartate (NMDA) NR2B subtype antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203899193359-26-1C21H27NO3 ·HCl10 mg/50 mg
  • CP 465022 hydrochloride
    AMPA antagonist which is selective, non-competitive and displays anti-convulsant activity.
    Katalog #CAS NummerSummenformelMenge
    sc-205272199655-36-2C26H24ClFN4O ·HCl10 mg/50 mg
  • CPCCOEt
    The compound CPCCOEt is a reversible and non-competitive antagonist of type 1α metabotropic glutamate receptor activation.
    Katalog #CAS NummerSummenformelMenge
    sc-200481179067-99-3C13H13NO45 mg/25 mg
  • CX546
    AMPA receptor potentiator which is specifically bound to agonist bound non-desensitized receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-205278215923-54-9C14H17NO310 mg/50 mg
  • D-AP3
    Katalog #CAS NummerSummenformelMenge
    sc-211171128241-72-5C3H8NO5P5 mg
  • D-AP7
    More active form of DL-AP7
    Katalog #CAS NummerSummenformelMenge
    sc-20301681338-23-0C7H16NO5P5 mg
  • D-Aspartic acid
    Endogenous NMDA receptor agonist with similar activity to the L-isomer. Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.
    Katalog #CAS NummerSummenformelMenge
    sc-2025621783-96-6C4H7NO41 g
  • D-CPP-ene
    Potent, competitive N-methyl-D-aspartic acid (NMDA) antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203910117414-74-1C8H15N2O5P10 mg
  • D-Cycloserine
    Reported to improve memory-dependent tasks in rats. Partial agonist of NMDA receptors at the glycine modulatory site.
    Katalog #CAS NummerSummenformelMenge
    sc-22147068-41-7C3H6N2O2200 mg/1 g
  • D-Quisqualic acid
    Katalog #CAS NummerSummenformelMenge
    sc-35885752809-07-1 (L-isomer)C5H7N3O510 mg
  • D(-)-2-Amino-4-phosphonobutanoic acid (D-AP4)
    NMDA antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20042978739-01-2C4H8NO5P-25 mg
  • D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)
    A selective antagonist of the NMDA receptors. Antagonizes amino acid- and electrically-induced synaptic excitations. Protects neurons against oxidative damage, increasing levels of SOD, catalase, and GSH.
    Katalog #CAS NummerSummenformelMenge
    sc-20043479055-68-8C5H12NO5P5 mg
  • DCB
    Allosteric ligand for the metabotropic glutamate receptor mGlu5; displays neutral modulation. Does not affect agonist-stimulated mGlu5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB and DMeOB.
    Katalog #CAS NummerSummenformelMenge
    sc-2035606971-97-7C14H10Cl2N210 mg/50 mg
  • Desmethyl-YM 298198
    Katalog #CAS NummerSummenformelMenge
    sc-361167299901-57-8C17H20N4OS.HCl10 mg/50 mg
  • Dextromethorphan Hydrobromide
    An NMDA receptor agonist that is the d-form of racemethorphan, where it is widely used as a cough suppressant. Newer uses include its anticonvulsive and neuro-protective properties. It was also found to improve cerebral ischemia.
    Katalog #CAS NummerSummenformelMenge
    sc-204716125-69-9C18H25NO ·HBr5 g/10 g
  • DFB
    Selective allosteric potentiator of metabotropic glutamate receptor subtype 5 (mGlu5).
    Katalog #CAS NummerSummenformelMenge
    sc-20391815332-10-2C14H10F2N210 mg/50 mg
  • DL-2-Amino-3-phosphonopropionic acid (AP3)
    An inhibitor of phosphoserine phosphatase and antagonist of mGluR, blocking mGluR-mediated phosphoinositide turnover. D-AP3 produces phosphoserine phosphatase inhibition and L-AP3 both antagonizes mGluR and inhibits phosphoserine phosphatase with similar potency.
    Katalog #CAS NummerSummenformelMenge
    sc-20043320263-06-3C3H8NO5P50 mg
  • DL-2-Amino-5-phosphonovaleric acid (AP5)
    Shown to be a potent and selective NMDA antagonist which causes antagonism of synaptic and amino-acid induced excitation in nerves.
    Katalog #CAS NummerSummenformelMenge
    sc-20150376326-31-3C5H12NO5P10 mg/50 mg
  • DL-2-Aminoadipic acid
    An excitatory amino acid analogue, which functions as a glutamine synthetase inhibitor.
    Katalog #CAS NummerSummenformelMenge
    sc-255121542-32-5C6H11NO41 g/5 g
  • DL-AP7
    A competitive antagonist of the ionotropic glutamate receptor, NMDA.
    Katalog #CAS NummerSummenformelMenge
    sc-20302878966-69-5C7H16NO5P5 mg
  • DMEOB
    Negative allosteric modulator at mGlu5. Exhibits reversible non-competitive inhibition of mGlu5-mediated responses.
    Katalog #CAS NummerSummenformelMenge
    sc-20356940252-74-2C16H16N2O210 mg/50 mg
  • Domoic acid
    An analogue of the neurotransmitter glutamate and an effective excitatory neurotransmitter that activates kainate subtype glutamate receptors
    Katalog #CAS NummerSummenformelMenge
    sc-20044614277-97-5C15H21NO61 mg/5 mg
  • E4CPG
    Group I/group II metabotropic glutamate receptor antagonist which is more potent than (RS)-MCPG.
    Katalog #CAS NummerSummenformelMenge
    sc-205943n.n.C11H13NO410 mg/50 mg
  • EGLU
    Selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord. Assumed to be a group II mGlu receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-205944n.n.C7H13NO410 mg/50 mg
  • Eliprodil
    Non-competitive NR2B-selective NMDA antagonist. Noncardiac drug with neuroprotective properties.
    Katalog #CAS NummerSummenformelMenge
    sc-203939119431-25-3C20H23ClFNO10 mg/50 mg
  • Felbamate
    Anticonvulsant, acting as an antagonist at the NMDA-associated glycine binding site.
    Katalog #CAS NummerSummenformelMenge
    sc-20357925451-15-4C11H14N2O410 mg/50 mg
  • Fenobam
    A selective non-competitive antagonist of the mGluR-5 receptor. Produces inverse agonist activity through an allosteric modulatory site. Demonstrates anxiolytic effects.
    Katalog #CAS NummerSummenformelMenge
    sc-20260857653-26-6C11H11ClN4O25 mg/25 mg
  • gamma-D-Glutamylaminomethylsulfonic acid
    This product is a selective antagonist of kainate/quisqualate.
    Katalog #CAS NummerSummenformelMenge
    sc-29500590237-02-8C6H12N2O6S1 mg/5 mg
  • γDGG
    Broad spectrum glutamate receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-2037286729-55-1C7H12N2O550 mg
  • Gavestinel
    Katalog #CAS NummerSummenformelMenge
    sc-361183153436-22-7C18H11Cl2N2O3Na10 mg/50 mg
  • GYKI 47261 dihydrochloride
    Non-competitive AMPA antagonist receptor (IC50 = 2.5 μM). In vivo, displays broad spectrum anticonvulsive activity and neuroprotective effects.
    Katalog #CAS NummerSummenformelMenge
    sc-203993220445-20-5C18H15ClN4 ·2HCl ·xH2O10 mg/50 mg
  • GYKI 52466 dihydrochloride
    Selective non-competitive allosteric AMPA receptor antagonist. Anticonvulsant; skeletal muscle relaxant. Exhibits anti-proliferative effects in transformed cells.
    Katalog #CAS NummerSummenformelMenge
    sc-203591102771-26-6C17H15N3O2•2HCl•xH2O10 mg/50 mg
  • HexylHIBO
    Group I mGlu antagonist (receptor). In vitro, decreases sEPSCs in rat pyramidal neurons.
    Katalog #CAS NummerSummenformelMenge
    sc-203597334887-43-3C12H20N2O410 mg/50 mg
  • (±)-HIP-A
    Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC50 = 1.6 μM) rather than [3H]L-glutamate uptake (IC50 = 18 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 43 and 8 μM respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-203598227619-64-9C6H8N2O410 mg
  • HIP-B
    Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC550= 1.2 μM) rather than [3H]L-glutamate uptake (IC50 = 16.9 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 35 and 45 μM respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-203599227619-65-0C6H8N2O410 mg
  • HomoAMPA
    Higher homologue of AMPA. Compound is completely inactive at ionotropic glutamate receptors but instead is a relatively potent and highly mGlu6 subtype selective metabotropic glutamate receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-204001n.n.C8H12N2O410 mg/50 mg
  • Homoquinolinic acid
    An analog of glutamic acid shown to excite rat cortical neurons and also be a neurotoxic agent. Found to specifically target the NR2A/B subunit of NMDA.
    Katalog #CAS NummerSummenformelMenge
    sc-200456490-75-5C8H7NO45 mg/25 mg
  • Ibotenic acid
    A conformationally restricted analogue of glutamic acid which is a useful tool in morphological and functional analysis of central neuronal systems in vivo and in vitro.
    Katalog #CAS NummerSummenformelMenge
    sc-2004492552-55-8C5H6N2O41 mg/5 mg
  • Ibotenic acid monohydrate
    A hydrate of Ibotenic acid and a conformationally restricted analogue of glutamic acid which is a useful tool in morphological and functional analysis of central neuronal systems in vivo and in vitro.
    Katalog #CAS NummerSummenformelMenge
    sc-29517260573-88-8n.n.1 mg/5 mg
  • IEM 1460
    Adamantane derivative. Open-channel blocker of AMPA currents; selectively blocks GluR2-lacking, Ca2+-permeable AMPA receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204007121034-89-7C19H37N2Br•HBr10 mg/50 mg
  • IEM 1754 dihydrobromide
    Katalog #CAS NummerSummenformelMenge
    sc-362747C16H30N2.2HBr162831-31-410 mg/50 mg
  • IEM 1925 dihydrobromide
    Katalog #CAS NummerSummenformelMenge
    sc-362748258282-23-4C17H28N2.2HBr10 mg/50 mg
  • Ifenprodil Tartrate Salt
    Shown to be a NMDA receptor antagonist, believed to act at the polyamine site. A neuroprotective agent, an alpha-adrenergic central and peripheral vasodilator, and an alpha ligand.
    Katalog #CAS NummerSummenformelMenge
    sc-29517323210-56-2C21H27NO25 mg/10 mg
  • Ifenprodil hemitartrate
    NMDA receptor antagonist, acting at the polyamine site. Also an α-adrenergic vasodilator. σ2 ligand displaying about 3-fold selectivity over σ 1 sites.
    Katalog #CAS NummerSummenformelMenge
    sc-20360123210-58-4(C21H27NO2)2 ·C4H6O610 mg/50 mg
  • Ivermectin
    Positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Also modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM).
    Katalog #CAS NummerSummenformelMenge
    sc-20360970288-86-7C48H74O14 ·(B1a ·form)100 mg/1 g
  • JNJ 16259685
    Sub-nanomolar potent, non-competitive mGlu1 antagonist. Inhibits glutamate-induced Ca2+ response at the human mGluR1. Selective over mGluR5.
    Katalog #CAS NummerSummenformelMenge
    sc-202670409345-29-5C20H23NO35 mg/25 mg
  • Joro Spider Toxin
    Originally isolated from the spider Nephila clavata, shown to selectively block postsynaptic glutamate potentials and quisqualate-sensitive glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-200453112163-33-4C27H47N7O6100 µg
  • Kynurenic acid
    A potential ligand of GPR35 G-protein-coupled receptor, antagonist of excitatory amino acids (EAA) and N-methyl-D-aspartate (NMDA) receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-202683492-27-3C10H7NO3250 mg/1 g
  • Kynurenic acid sodium salt
    A sodium salt of Kynurenic acid. A potential ligand of GPR35 G-protein-coupled receptor, antagonist of excitatory amino acids (EAA) and N-methyl-D-aspartate (NDMA) receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-358835492-27-3 (non-salt)C10H6NO3•Na100 mg
  • L-(-)-threo-3-Hydroxyaspartic acid
    Potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor.
    Katalog #CAS NummerSummenformelMenge
    sc-2040337298-99-9C4H7NO510 mg
  • L-689,560
    A selective antagonist at the glycine-binding site of the NMDA receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-202684139051-78-8C17H15N3O3Cl21 mg
  • L-701,252
    NMDA receptor antagonist acting at the glycine site1. Anticonvulsant.
    Katalog #CAS NummerSummenformelMenge
    sc-205726151057-13-5C13H10ClNO310 mg/50 mg
  • L-701,324
    Katalog #CAS NummerSummenformelMenge
    sc-361224142326-59-8C21H14CINO310 mg/50 mg
  • L-AP3
    Selective antagonist of the PI-linked metabotropic glutamate response.
    Katalog #CAS NummerSummenformelMenge
    sc-20220123052-80-4C3H8NO5P5 mg/25 mg
  • L-AP6
    QUIS-sensitized L-AP4 receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20220278944-89-5C6H14NO5P5 mg/1 mg
  • L-BMAA hydrochloride
    Monocarboxylic, neurotoxic amino acid; can act at the strychnine-insensitive glycine modulatory site to modify the activity of N-methyl-D-aspartate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20404915920-93-1C4H10N2O2.HCl10 mg
  • L-CCG-I
    Potent group II mGluR agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203097117857-93-9C6H9NO41 mg
  • L-CCG-IV
    Potent NMDA receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203098117857-95-1C6H9NO41 mg
  • L-Cysteinesulfinic acid
    An amino acid neurotransmitter.
    Katalog #CAS NummerSummenformelMenge
    sc-2036201115-65-7C3H7NO4S100 mg
  • L-Glutamic acid γ-(α-naphthylamide) monohydrate
    Katalog #CAS NummerSummenformelMenge
    sc-21521781012-91-1C15H16N2O3⋅H2O25 mg/1 g
  • L-Glutamic acid γ-(β-naphthylamide)
    Katalog #CAS NummerSummenformelMenge
    sc-21521914525-44-1C15H16N2O3100 mg/1 g
  • L-Glutamic acid γ-(3-carboxy-4-hydroxyanilide)
    Katalog #CAS NummerSummenformelMenge
    sc-21521574929-17-2C12H14N2O610 mg/250 mg
  • L-Pyroglutamic acid 4-nitroanilide
    Katalog #CAS NummerSummenformelMenge
    sc-21171166642-35-1C11H11N3O425 mg
  • L-Quisqualic acid
    Quisqualate acts as an agonist for metabotropic glutamate receptor 1 (mGluR1), and can be used to differentiate between mGluR1 and mGluR4.
    Katalog #CAS NummerSummenformelMenge
    sc-20046752809-07-1C5H7N3O55 mg/25 mg
  • L-trans-Pyrrolidine-2,4-dicarboxylic acid
    An inhibitior of glutamate transport. Demonstrates an increase in extracellular glutamate levels, leading to massive NMDAR-mediated neuronal death with no observed agonism of NMDAR.
    Katalog #CAS NummerSummenformelMenge
    sc-20047764769-66-0C6H9NO45 mg/25 mg
  • L(+)-2-Amino-4-phosphonobutanoic acid (L-AP4)
    An amino-acid derivative and a mGluR4 and mGluR6 metabotropic glutamate receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20043223052-81-5C4H10NO5P5 mg
  • L(+)-2-Amino-5-phosphonovaleric acid
    This product has been shown to be an NMDA antagonist. It has also been oberved to be an agonist at quisqualate-sensitized AP6 site, where it is more potent than the D-isomer. There is evidence that L-AP5 can preferentially block cone signals in the rat retina.
    Katalog #CAS NummerSummenformelMenge
    sc-35859979055-67-7C5H12NO5P5 mg/50 mg
  • Lamotrigine isethionate
    A water soluble phenyltriazine compound, which functions as an inhibitor of voltage gated sodium channels of presynaptic neurons.
    Katalog #CAS NummerSummenformelMenge
    sc-218654113170-86-8C9H7Cl2N5.C2H6O4S10 mg
  • LY 233053
    Katalog #CAS NummerSummenformelMenge
    sc-361238125546-04-5C8H13N5O21 mg/10 mg
  • LY 235959
    Katalog #CAS NummerSummenformelMenge
    sc-361239137433-06-8C11H20NO5P10 mg/50 mg
  • LY 341495
    Katalog #CAS NummerSummenformelMenge
    sc-361244201943-63-7C20H19NO51 mg/10 mg
  • LY 341495 disodium salt
    Katalog #CAS NummerSummenformelMenge
    sc-362765n.n.C20H17NNa2O51 mg/10 mg
  • LY 354740
    This compound is a highly selective and potent group II (mGlu 2/3) receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-204064176199-48-7C8H11NO410 mg/50 mg
  • LY 367385
    Katalog #CAS NummerSummenformelMenge
    sc-361246198419-91-9C10H11NO410 mg/50 mg
  • LY 379268
    Katalog #CAS NummerSummenformelMenge
    sc-361247191471-52-0C7H9NO510 mg/50 mg
  • LY 395756
    Katalog #CAS NummerSummenformelMenge
    sc-359013842679-66-4C9H13NO410 mg/50 mg
  • LY 456236 hydrochloride
    Selective mGlu1 antagonist. Reduces formalin-induced hyperalgesic behavior in both mouse and rat with ED50 values of 28 and 16.3 mg/kg, respectively.
    Katalog #CAS NummerSummenformelMenge
    sc-203625338738-57-1C16H15N3O2.HCl10 mg/50 mg
  • LY 487379 hydrochloride
    Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204065353231-17-1C21H19F3N2O4S ·HCl10 mg/50 mg
  • MAP4
    Selective agonist for group III mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-202221157381-42-5C5H12NO5P5 mg
  • Matrine
    An alkaloid. Has antiulcerogenic activity against stress ulcer in rat. It depresses both glutamate-induced responses and neurally evoked excitatory junctional potentials.
    Katalog #CAS NummerSummenformelMenge
    sc-205741519-02-8C15H24N2O100 mg/500 mg
  • Memantine hydrochloride
    An antagonist at the NMDA receptor, binding to the ion channel site. Used in the treatment of Parkinsonism.
    Katalog #CAS NummerSummenformelMenge
    sc-20362841100-52-1C12H21N ·HCl50 mg
  • mGluR5 Ligand, CDPPB
    A pyrazole amide compound that crosses the blood-brain barrier and acts as a potent, selective, reversible, positive allosteric modulator for metabotropic glutamate receptor subtype 5 (mGluR5). This also exerts anti-psychotic-like effects. It is reported to potentiate the response to glutamate (~300 nM) in CHO-mGluR5 cells (EC50 = 10 nM for human, 4-fold potentiation; 20 nM for rat, 4.3-fold potentiation) and reverse amphetamine-induced disruption of pre-pulse inhibition (PPI) in rats. The specificity was determined using a panel of kinases and receptors. It does not potentiate the activity of other glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-221942781652-57-1C23H16N4O1 mg
  • (-)-MK 801 maleate
    Katalog #CAS NummerSummenformelMenge
    sc-36125377086-19-2C16H15N.C4H4O410 mg/50 mg
  • (+)-MK 801 Maleate
    A selective non-competitive antagonist of the NMDA receptor. Interacts with NMDA-associated ion channel, blocking Ca2+ flux and NMDA-induced depolarization. Demonstrates neuroprotective effects.
    Katalog #CAS NummerSummenformelMenge
    sc-20313777086-22-7C16H15N•C4H4O410 mg
  • MMPIP hydrochloride
    Potent allosteric mGlu7-selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC50 = 15 nM), indicating inverse agonist activity.
    Katalog #CAS NummerSummenformelMenge
    sc-204093479077-02-6C19H15N3O3 ·HCl1 mg/10 mg
  • MNI caged kainic acid
    Katalog #CAS NummerSummenformelMenge
    sc-359014487-79-6 (uncaged)C19H23N3O610 mg
  • MNI-caged-L-glutamate
    Katalog #CAS NummerSummenformelMenge
    sc-361257295325-62-1C14H17N3O610 mg/50 mg
  • MNI-caged-NMDA
    Katalog #CAS NummerSummenformelMenge
    sc-361258n.n.C14H17N3O610 mg
  • MPDC
    A strong inhibitor of the Na+-dependent high-affinity synaptosomal glutamate transporter.
    Katalog #CAS NummerSummenformelMenge
    sc-204097n.n.C7H9NO410 mg
  • MPPG
    Potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons. Antagonist of mGlu receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203143169209-65-8C9H12NO5P10 mg/50 mg
  • MSOP
    Selective group III metabotropic glutamate receptor antagonist. Displays an apparent Kd of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Has no activity on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons.
    Katalog #CAS NummerSummenformelMenge
    sc-20363766515-29-5C4H10NO6P10 mg/50 mg
  • MTEP
    A brain-permeable (thiazole-pyridine)alkyne compound that acts as a potent, selective and non-competitive mGluR5 antagonist with in vivo anxiolytic activity in a rodent model. Highly selective and potent with a 5-fold higher anxiolytic activity than MPEP. Shows fewer off-target effects than MPEP.
    Katalog #CAS NummerSummenformelMenge
    sc-205956n.n.C11H8N2S5 mg/25 g
  • MTEP hydrochloride
    Katalog #CAS NummerSummenformelMenge
    sc-361267n.n.C11H8N2S.HCl10 mg/50 mg
  • MTPG
    Group II/group III mGlu antagonist, showing selectivity for group II in electrophysiological studies. Potent antagonist for (1S,3S)-ACPD-sensitive receptors; preference for GluR2 and GluR3 subtypes.
    Katalog #CAS NummerSummenformelMenge
    sc-204106169209-66-9C10H11N5O210 mg/50 mg
  • N-(3-Aminopropyl)cyclohexylamine
    An inhibitor of spermine synthase. Described to specifically deplete spermidine and spermine levels in cultured rat hepatoma cells. Anatagonizes the facilitating effect of spermidine on NMDLA-induced seizures.
    Katalog #CAS NummerSummenformelMenge
    sc-2027153312-60-5C9H20N21 g
  • N-(4-Hydroxyphenylacetyl)-spermine
    A wasp toxin analog of naturally occurring PhTX-433. This is a very potent glutamate antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-200466130210-32-1C18H32N4O2250 µg
  • N-(4-Hydroxyphenylpropanoyl) spermine trihydrochloride
    Wasp toxin analog. More potent than PhTX-343 at locust NMJ. Antagonist of the quisqualate-sensitive L-glutamate receptor (quis-GluR) of locust muscle.
    Katalog #CAS NummerSummenformelMenge
    sc-204109130631-59-3C19H34N4O2 ·3HCl250 µg
  • N-Acetyl-Asp-Glu-OH
    Endogenous neurotransmitter with high affinity for the brain glutamate receptor. mGluR3 activator. NMDA receptor antagonist. Neuroprotective.
    Katalog #CAS NummerSummenformelMenge
    sc-2027173106-85-2C11H16N2O810 mg/50 mg
  • N-Acetylglycyl-D-glutamic acid
    Excitatory peptide, more potent than L-glutamic acid at inducing seizures in mice.
    Katalog #CAS NummerSummenformelMenge
    sc-204111135701-69-8C9N14N2O610 mg/50 mg
  • N-Glutaryl-Gly-Phe-4-methoxy-β-naphthylamide
    Katalog #CAS NummerSummenformelMenge
    sc-215459100940-58-7C27H29N3O610 mg/25 mg
  • N-Glutaryl-L-phenylalanine p-nitroanilide
    Katalog #CAS NummerSummenformelMenge
    sc-2154605800-34-0C20H21N3O61 g/5 g
  • N20C hydrochloride
    Non-competitive NMDA receptor open-channel blocker. Binds to receptor-associated ion channels and prevents glutamate-induced Ca2+ influx. Displays neuroprotective activity in vivo, and reportedly to be a brain-penetrant.
    Katalog #CAS NummerSummenformelMenge
    sc-20411676991-05-4C17H20N2O•HCl10 mg/50 mg
  • Neuronal Differentiation Inducer III
    A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation in various stem/progenitor cells.
    Katalog #CAS NummerSummenformelMenge
    sc-222058n.n.C11H10N2O2S10 mg
  • NPEC-caged-(1S,3R)-ACPD
    Katalog #CAS NummerSummenformelMenge
    sc-359016n.n.C16H18N2O810 mg/50 mg
  • NPEC-caged-(S)-3,4-DCPG
    Katalog #CAS NummerSummenformelMenge
    sc-359017n.n.C19H16N2O1010 mg/50 mg
  • NPEC-caged-(S)-AMPA
    Caged compound; a 1-(2-nitrophenyl)ethyl caged version of (S)-AMPA agonist at the AMPA receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-358838n.n.C16H17N3O810 mg
  • NPEC-caged-D-AP5
    Katalog #CAS NummerSummenformelMenge
    sc-362772n.n.C14H19N2O9P10 mg/50 mg
  • NPEC-caged-LY 379268
    Katalog #CAS NummerSummenformelMenge
    sc-359019n.n.C16H16N2O910 mg
  • NS 3763
    Selective non-competitive kainate receptor antagonist; displays selectivity for GLUK5 subunit-containing receptors (IC50 values are 1.6 and > 30 mM for homomeric GLUK5 and GLUK6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC50 >> 30 mM).
    Katalog #CAS NummerSummenformelMenge
    sc-20365170553-45-6C22H16N2O610 mg/50 mg
  • O-Phospho-L-serine
    L-AP4 agonist. Competitive NMDA antagonist. Has affinity for type IV, but not type I, metabotropic glutamate receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-202257407-41-0C3H8NO6P1 g
  • PCCG-13
    A potent, selective and competitive antagonist of PLD-coupled mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-205962n.n.C12H13NO41 mg
  • PCCG-4
    Selective group II mGluR antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-222130n.n.C12H13NO41 mg/5 mg
  • Pentamidine isethionate
    Exhibits inhibitory actions on constitutive nitric oxide synthase in the brain and acts as a NMDA Glu antagonist. Antimicrobial, neuroprotective agent.
    Katalog #CAS NummerSummenformelMenge
    sc-204176140-64-7C19H24N4O2•2C2H6O4S50 mg
  • PEPA
    Allosteric potentiator of AMPA desensitization. Decreases rate of onset of desensitization and potentiates steady-state equilibrium currents induced by Glu with splic variant and subunit selectivity. Enhances post-ischemic memory impairment in rats post i.v. administration.
    Katalog #CAS NummerSummenformelMenge
    sc-204178141286-78-4C16H16F2N2O4S210 mg/50 mg
  • PHCCC
    Katalog #CAS NummerSummenformelMenge
    sc-361292n.n.C17H14N2O310 mg/50 mg
  • Philanthotoxin 74
    Subtype-selective AMPA receptor antagonist that inhibits GluR1/2 but not GluR2/3 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204189401601-12-5C24H42N4O3 ·2HCl1 mg/10 mg
  • Piracetam
    Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux. Through AMPA receptors, potentiates Na+ influx. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-2041967491-74-9C6H10N2O25 g/25 g
  • PMPA (NMDA antagonist)
    Short-chain competitive NMDA antagonist. Displays Ki values of 0.84, 2.74, 3.53 and 4.16 μM at NR2A, NR2B, NR2C and NR2D subunit-containing receptors respectively. Selective over AMPA receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204850113919-36-1C6H13N2O5P10 mg/50 mg
  • PPDA
    Subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors (Ki values are 0.096, 0.125, 0.31 and 0.55 μM for NR2C, NR2D, NR2B and NR2A subunits respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-204210n.n.C21H18N2O5 ·xH2O10 mg/50 mg
  • PPPA
    Competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors (Ki values are 0.13, 0.47, 1.10 and 3.86 μM for NR2A, NR2B, NR2C and NR2D subunits respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-204212n.n.C9H18NO5P10 mg/50 mg
  • Putrescine dihydrochloride
    A compound that binds to the polyamine modulatory site of the NMDA (N-methyl D-aspartate) receptor and potentiate NMDA-induced currents.
    Katalog #CAS NummerSummenformelMenge
    sc-202786333-93-7C4H12N2 ·2HCl1 g
  • Quinolinic acid
    Metabolite of tryptophan. Putative NMDA receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20322689-00-9C7H5NO41 g
  • (R,S)-ATPA
    Potent and selective agonist of the GluR5 subtype of the kainate receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-203232140158-50-5C10H16N2O41 mg/5 mg
  • (R)-(+)-HA-966
    Katalog #CAS NummerSummenformelMenge
    sc-361303123931-04-4C4H8N2O210 mg/50 mg
  • (R)-3-Carboxy-4-hydroxyphenylglycine
    Moderately potent NMDA and AMPA/kainate receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20487113861-03-5C9H9NO510 mg/50 mg
  • (R)-3,4-DCPG
    AMPA receptor antagonist with little activity at kainate receptors and weak activity at NMDA receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204227n.n.C10H9NO610 mg/50 mg
  • (R)-4-Carboxyphenylglycine
    Katalog #CAS NummerSummenformelMenge
    sc-361304134052-68-9C9H9NO410 mg/50 mg
  • (R)-AMPA
    Katalog #CAS NummerSummenformelMenge
    sc-36130583654-13-1C7H10N2O410 mg
  • (R)-CPP
    Highly potent NMDA receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-202308126453-07-4C8H17N2O5P1 mg/10 mg
  • Remacemide hydrochloride
    Katalog #CAS NummerSummenformelMenge
    sc-361307111686-79-4C17H20N2O.HCl10 mg/50 mg
  • Ro 01-6128
    Katalog #CAS NummerSummenformelMenge
    sc-362789302841-86-7C17H17NO310 mg/50 mg
  • Ro 04-5595 hydrochloride
    Selective antagonist for NR2B-containing NMDA receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204885194089-07-1C19H22ClNO2.HCl10 mg/50 mg
  • Ro 25-6981 maleate
    NMDA agonist. Potent and selective activity-dependent blocker NR2B subunit-containing NMDA receptors . IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Acts as a neuroprotectant in vivo and in vitro.
    Katalog #CAS NummerSummenformelMenge
    sc-204887169274-78-6C22H29NO2 ·C4H4O41 mg/10 mg/50 mg
  • Ro 67-4853
    Katalog #CAS NummerSummenformelMenge
    sc-362790302841-89-0C19H19NO410 mg/50 mg
  • Ro 8-4304 Hydrochloride
    NMDA receptor antagonist (IC50 = 0.4 μM) that displays > 100 fold selectivity for NR2B-containing receptors over NR2A-containing receptors. Displays an activity-dependent mechanism of NMDA antagonism and is competitive with respect to spermine.
    Katalog #CAS NummerSummenformelMenge
    sc-204241195988-65-9C21H23FN2O3 ·HCl10 mg/50 mg
  • (RS)-(Tetrazol-5-yl)glycine
    Highly potent NMDA receptor agonist Potent NMDA receptor agonist, approximately 20 times more active than NMDA.
    Katalog #CAS NummerSummenformelMenge
    sc-205495138199-51-6C3H5N5O210 mg/50 mg
  • (RS)-α-Methyl-3-carboxy-4-hydroxyphenylglycine
    This is a potent antagonist of both L-AP4 and L-CCG-I-induced depressions of forskolin-stimulated cAMP production. It shows preferential antagonist activity versus L-CCG-I. Group I/group II mGluR antagonist at cloned receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-222264n.n.C10H11NO55 mg
  • (RS)-3-Hydroxyphenylglycine
    Agonist at PI-linked metabotropic glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20424631932-87-3C8H9NO310 mg/50 mg
  • (RS)-3,4-DCPG
    Systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG (mGlu8-selective agonist) or (R)-3,4,-DCPG (AMPA/NMDA antagonist).
    Katalog #CAS NummerSummenformelMenge
    sc-204247n.n.C10H9NO610 mg/50 mg
  • (RS)-3,5-DHPG
    Selective group I metabotropic glutamate receptor agonist which activates both mGlu1 and mGlu5.Reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D.
    Katalog #CAS NummerSummenformelMenge
    sc-20549619641-83-9C8H9NO410 mg/50 mg
  • (RS)-4-Bromo-homo-ibotenic acid
    Potent AMPA receptor agonist. Selective but relatively non-potent group I mGluR agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20324471366-32-0C6H7N2O4Br5 mg
  • (RS)-4-Carboxyphenylglycine
    Katalog #CAS NummerSummenformelMenge
    sc-3613197292-81-1C9H9NO410 mg/50 mg
  • (RS)-4C3H-PG
    'Broad spectrum' EAA ligand
    Katalog #CAS NummerSummenformelMenge
    sc-203245134052-66-7C9H9NO510 mg/50 mg
  • (RS)-AMPA hydrobromide
    More water soluble form of sc-200437.
    Katalog #CAS NummerSummenformelMenge
    sc-20324677521-29-0C7H10N2O4 ·HBr1 mg
  • (RS)-APICA
    A rigidified analog of MPPG; a selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses an unusual inverse agonist-like action.
    Katalog #CAS NummerSummenformelMenge
    sc-204248n.n.C10H12NO5P10 mg/50 mg
  • (RS)-CPPG
    Most potent group II/III mGluR antagonist, with approx. 20-fold selectivity for group III over group II.
    Katalog #CAS NummerSummenformelMenge
    sc-203448183364-82-1C11H14NO5P5 mg/25 mg
  • (RS)-MCPG
    A non-selective antagonist of group I/II mGluRs. Used as a tool for probing the mGluR system.
    Katalog #CAS NummerSummenformelMenge
    sc-202325146669-29-6C10H11NO45 mg
  • (RS)-MCPG disodium salt
    A non-selective group I/group II metabotropic glutamate receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-358840n.n.C10H9NNa2O410 mg
  • (RS)-MSPG
    A non-selective antagonist of mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-203247169209-64-7C9H11NO5S10 mg
  • (RS)-PPG
    Potent and selective group III mGluR agonist, with a subtype specificity towards the mGlu3 receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-202797120667-15-4C8H10NO5P5 mg
  • S-(+)-CBPG
    This is a potent and selective, structurally new group I mGluR antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-222268n.n.C8H11NO41 mg/5 mg
  • S-(N,N-Diethylcarbamoyl)glutathione
    Katalog #CAS NummerSummenformelMenge
    sc-220012157723-51-8C15H26N4O7S5 mg
  • S-(N,N-Diethylcarbamoyl)glutathione Sulfoxide
    Katalog #CAS NummerSummenformelMenge
    sc-220013n.n.C14H26N4O8S5 mg
  • S-Sulfo-L-cysteine sodium salt
    EAA receptor agonist. Agonist at mGlu1α and mGlu5a subtypes expressed in clonal RGT cell lines.
    Katalog #CAS NummerSummenformelMenge
    sc-2054981637-71-4C3H6NO5S2Na.xH2O10 mg/50 mg
  • (S)-(-)-5-Fluorowillardiine
    Katalog #CAS NummerSummenformelMenge
    sc-361326140187-23-1C7H8FN3O410 mg/50 mg
  • (S)-(-)-5-Iodowillardiine
    Katalog #CAS NummerSummenformelMenge
    sc-361327140187-25-3C7H8IN3O410 mg/50 mg
  • (S)-3-Carboxy-4-hydroxyphenylglycine
    Mixed group II mGlu agonist and group I metabotropic glutamate receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20368955136-48-6C9H9NO510 mg/50 mg
  • (S)-3-Hydroxyphenylglycine
    Agonist at group I metabotropic glutamate receptors (mGlu1) having no effect at mGlu2 or mGlu4.
    Katalog #CAS NummerSummenformelMenge
    sc-20425471301-82-1C8H9NO310 mg/50 mg
  • (S)-3,4-DCPG
    Potent, selective mGlu8a agonist (EC50 = 31 nM). Displays > 100-fold selectivity over mGlu1-7 and displays little/no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo. Also a potent anticonvulsant in mice in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-204255201730-11-2C10H9NO610 mg/50 mg
  • (S)-3,5-DHPG
    Selective group I mGlu receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-204256162870-29-3C8H9NO45 mg/10 mg
  • (S)-4C-PG
    Competitve group I mGluR antagonist, with selectivity for mGlu1 over mGlu5 receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-203449134052-73-6C9H9NO41 mg/5 mg/50 mg
  • (S)-4C3H-PG
    Agonist for group II mGluRs. Competitive antagonist for group I mGluR1; mixed effects at mGluR5.
    Katalog #CAS NummerSummenformelMenge
    sc-20324985148-82-9C9H9NO51 mg/5 mg
  • (S)-CPW 399
    Subtype-selective weakly desensitising AMPA agonist. At GluR1 and GluR2 subunit-containing AMPA receptors, exhibits potent agonist activity. Excitotoxic in vitro.
    Katalog #CAS NummerSummenformelMenge
    sc-203690389888-02-2C10H13N3O410 mg/50 mg
  • (S)-HexylHIBO
    Group I mGlu antagonist. Enantiomer of hexylHIBO.
    Katalog #CAS NummerSummenformelMenge
    sc-203691334887-48-8C12H20N2O410 mg/50 mg
  • (S)-MCPG
    An antagonist of the group I/II mGluRs. Active isomer of (RS)-MCPG preparations. Affects spatial learning and blocks induction of LTP through interaction with the mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-202329150145-89-4C10H11NO45 mg/25 mg
  • (S)-MPPG
    This is the active isomer of (RS)-MPPG. It is a highly potent L-AP4-sensitive receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-222283201608-25-5C9H12NO5P1 mg/5 mg
  • (S)-MPPG (cyclic)
    This is a selective antagonist of group II mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-222284n.n.C10H12NO5P1 mg
  • Salsolinol-1-carboxylic acid
    An amino acid that occurs naturally in the CNS.
    Katalog #CAS NummerSummenformelMenge
    sc-20425957256-34-5C11H13NO410 mg/50 mg
  • SDZ 220-040
    Katalog #CAS NummerSummenformelMenge
    sc-361354174575-40-7C16H16Cl2NO6P10 mg/50 mg
  • SDZ 220-581
    Katalog #CAS NummerSummenformelMenge
    sc-361355n.n.n.n.10 mg/50 mg
  • SIB 1757
    A highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
    Katalog #CAS NummerSummenformelMenge
    sc-20427731993-01-8C12H11N3O10 mg/50 mg
  • SIB 1893
    Highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype.
    Katalog #CAS NummerSummenformelMenge
    sc-2032626266-99-5C14H13N10 mg/50 mg
  • Spermidine trihydrochloride
    Katalog #CAS NummerSummenformelMenge
    sc-360822334-50-9C7H19N3•3HCl1 g/5 g
  • SYM 2206
    Katalog #CAS NummerSummenformelMenge
    sc-361369173952-44-8C20H22N4O310 mg/50 mg
  • t-CAA
    This is a potent in vivo inhibitor of glutamate uptake and a Kainate receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-222334n.n.C6H9NO41 mg
  • TCN 238
    Katalog #CAS NummerSummenformelMenge
    sc-362803125404-04-8C12H11N310 mg/50 mg
  • TCS 46b
    Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.
    Katalog #CAS NummerSummenformelMenge
    sc-204328302799-86-6C22H23N3O10 mg/50 mg
  • Threo Ifenprodil hemitartrate
    Katalog #CAS NummerSummenformelMenge
    sc-36138174991-34-7C21H27NO2.½C4H6O610 mg/50 mg
  • (±)-threo-3-Methylglutamic acid
    A potent blocker of glutamate transport. Selective for EAAT2 and EAAT4 (IC50 values are 90, 109, 1600 and 1080 μM for EAAT2, EAAT4, EAAT1 and EAAT3 respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-20434463088-04-0C6H11NO410 mg/50 mg
  • Topiramate
    Anticonvulsant that antagonizes GluR5 kainate receptors (IC50 = 0.46 μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
    Katalog #CAS NummerSummenformelMenge
    sc-20435097240-79-4C12H21NO8S10 mg/50 mg
  • trans-1,2-homo-ACPD
    Selective antagonist for group II mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-208456n.n.C8H13NO45 mg
  • trans-1,3-homo-ACPD
    Equimolar mixture of (1R,3S)-homo-ACPD and (1S,3R)-homo-ACPD.
    Katalog #CAS NummerSummenformelMenge
    sc-205981n.n.C8H13NO45 mg
  • TRANS-ACPD
    An equimolar mixture of Trans-(1S,3R)-ACPD and Trans-(1R,3S)-APCD. Agonist of metabotropic glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20236767684-64-4C7H11NO410 mg/50 mg
  • (±)-trans-Azetidine-2,4-dicarboxylic acid
    Selective agonist for group I mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-203300161596-62-9C5H7NO41 mg
  • U-54494A hydrochloride
    NMDA antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-200479112465-94-8C18H24Cl2N2O··HCl5 mg/25 mg
  • UBP 282
    AMPA and kainate receptor antagonist that distinguishes between motoneuron and dorsal root kainate receptors. Inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres.
    Katalog #CAS NummerSummenformelMenge
    sc-203715544697-47-4C15H15N3O610 mg/50 mg
  • UBP 296
    Potent and selective GluR5-subunit containing kainate receptor antagonist (apparent Kd = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres. Has little or no action at NMDA or group I mGlu receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204366n.n.C15H15N3O610 mg/50 mg
  • UBP 301
    Kainate potent receptor antagonist (apparent Kd = 5.94 mM). Displays ~ 30-fold selectivity over AMPA receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203716569371-10-4C15H14IN3O610 mg/50 mg
  • UBP 302
    Potent and selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist; active enantiomer of UBP 296.
    Katalog #CAS NummerSummenformelMenge
    sc-204367n.n.C15H15N3O610 mg/50 mg
  • UBP1112
    A group III mGlu receptor antagonist that is selective (apparent Kd values are 5.1 and 488 μM for group III and group II mGlu receptors respectively; IC50 > 1 mM for group I, NMDA, AMPA and kainate receptors).
    Katalog #CAS NummerSummenformelMenge
    sc-204368n.n.C10H14NO5P10 mg/50 mg
  • VU 0155041
    Potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). In vivo models of Parkinson's disease, active following i.c.v. administration.
    Katalog #CAS NummerSummenformelMenge
    sc-204385n.n.C14H15Cl2NO310 mg/50 mg
  • VU 0155041 sodium salt
    A positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4).
    Katalog #CAS NummerSummenformelMenge
    sc-204386n.n.C14H14Cl2NNaO310 mg/50 mg
  • VU 0361737
    A selective positive allosteric modulator at mGlu4 receptors (EC50 values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors. Also a brain penetrant.
    Katalog #CAS NummerSummenformelMenge
    sc-3019761161205-04-4C13H11CIN2O210 mg/50 mg
  • VU 1545
    Positive allosteric modulator of metabotropic glutamate receptor 5 (mGlu5) (EC50 = 9.6 nM, Ki = 156 nM at rat mGlu5).
    Katalog #CAS NummerSummenformelMenge
    sc-204388890764-63-3C22H15FN4O310 mg/50 mg
  • WAY 213613
    Strong, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards metabotropic and ionotropic glutamate receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203720868359-05-1C16H13BrF2N2O410 mg/50 mg
  • XE-CCG-I
    Selective and highly active group II mGluR antagonist with a subtype specificity towards the mGlu3 receptor. XE-CCG-I has no activity towards group I and group III mGluRs.
    Katalog #CAS NummerSummenformelMenge
    sc-222421n.n.C21H21NO51 mg
  • YM 230888
    A selective mGLU1 antagonist reported to inhibit mGlu1-mediated inositol phosphate production.
    Katalog #CAS NummerSummenformelMenge
    sc-358843446257-23-4C19H28N4OS10 mg/50 mg
  • YM 298198 hydrochloride
    Katalog #CAS NummerSummenformelMenge
    sc-361412748758-45-4C18H22N4OS.HCl10 mg/50 mg
  • YM 90K hydrochloride
    Katalog #CAS NummerSummenformelMenge
    sc-361415154164-30-4C11H7N5O4.HCl10 mg/50 mg
  • Z-Cyclopentyl-AP4
    Group III mGlu receptor agonist that displays higher potency at mGlu4 than mGlu8 (EC50 values are 49 and 124 μM respectively) with no activity at mGlu7. Selectively inhibits synaptic activity in the lateral perforant pathway (IC50 values are 130 and 1859 μM in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4.
    Katalog #CAS NummerSummenformelMenge
    sc-204413103439-17-4C6H12NO5P10 mg/50 mg
  • ZJ 43
    Has been shown to be a potent inhibitor of glutamate carboxypeptidase II and III. a potent inhibitor of glutamate carboxypeptidase II and III.
    Katalog #CAS NummerSummenformelMenge
    sc-361420723331-20-2C12H20N2O71 mg/10 mg
  • ZK 200775
    Competitive AMPA/kainate antagonist; inhibits currents induced by AMPA, kainate and NMDA; Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-204421161605-73-8C14H15N3O6F3P10 mg/50 mg