| | Glutamatergics
- (±)-1-(1,2-Diphenylethyl)piperidine maleate
NMDA receptor ion channel blocker.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203732 | 36794-52-2 | C19H23N ·C4H4O4 | 10 mg/50 mg |
- 1-Aminocyclobutane-cis-1,3-dicarboxylic acid
A very potent, competitive and selective inhibitor of glutamate uptake.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200438 | 117488-23-0 | C6H9NO4 | 5 mg/25 mg |
- 1-Aminocyclobutane-trans-1,3-dicarboxylic acid
A very potent, competitive and selective inhibitor of glutamate uptake.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361072 | 73550-55-7 | C6H9NO4 | 10 mg/50 mg |
- 1-Aminocyclopentanecarboxylic acid
NMDA receptor antagonist acting at the glycine site.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202392 | 52-52-8 | C6H11NO2 | 10 mg |
- 1-Aminocyclopropane-1-carboxylic Acid
An agonist at the glycine modulatory site of the NMDA receptor. Mimics the effects of glycine on the NMDAR and competitively inhibits glycine-NMDAR binding.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202393 | 22059-21-8 | C4H7NO2 | 500 mg |
- 1-BCP
Centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203454 | 34023-62-6 | C13H15NO3 | 10 mg/50 mg |
- 1-Benzyl-APDC hydrochloride
A selective ligand of mGlu6 receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-220463 | n.n. | C13H16N2O4•HCl | 1 mg/5 mg |
- (1R,3R)-homo-ACPD
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-206296 | n.n. | C8H13NO4 | 5 mg |
- (1R,3S)-homo-ACPD
Inactive isomer of trans-1,3-homo-ACPD.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-206299 | n.n. | C8H13NO4 | 5 mg |
- (1S,3R)-ACPD
A rigid analog of glutamate. Excites metabotropic receptors with α-kainic acid-like action.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202009 | 111900-32-4 | C7H11NO4 | 5 mg/25 mg |
- (1S,3R)-homo-ACPD
Active isomer of trans-1,2-homo-ACPD. Highly selective agonist for group II mGluRs and has no effect at ionotropic excitatory amino acid receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205919 | n.n. | C8H13NO4 | 5 mg |
- (1S,3S)-homo-ACPD
Isomer of cis-1,3-homo-ACPD. Partial agonist for group II mGluRs. Displays no effect at ionotropic excitatory amino acid receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-206307 | n.n. | C8H13NO4 | 5 mg |
- (-/+)-2-amino-7-phosphonoheptanoic acid
This product is a NMDA antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-287806 | 85797-13-3 | C7H16NO5P | 2 mg/5 mg |
- 2,4-Dihydroxyphenylacetyl-L-asparagine
Component of various spider toxins and purported specific blocker of glutamate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203468 | 111872-98-1 | C12H14N2O6 | 10 mg/50 mg |
- (2R,3S)-Chlorpheg
A weakly active NMDA receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203775 | n.n. | C11H12ClNO4 | 10 mg |
- (2R,4R)-(+)-Azetidine-2,4-dicarboxylic acid
A selective pharmacological agent of the metabotropic glutamate (mGlu) receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205922 | 161596-63-0 | C5H7NO4 | 1 mg |
- (2R,4R)-APDC
A highly selective agonist for group II metabotropic glutamate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202408 | 169209-63-6 | C6H10N2O4 | 1 mg/5 mg |
- (2S,3S,4S)-2-Methyl-2-(carboxycyclopropyl)glycine
Selective group II mGluR antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202014 | 157141-16-7 | C7H11NO4 | 1 mg/5 mg |
- (2S,4R)-4-Methylglutamic Acid
A highly selective and potent agonist for kainate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-216338 | 31137-74-3 | C6H11NO4 | 5 mg |
- (2S,4S)-(-)-Azetidine-2,4-dicarboxylic acid
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-220844 | 161596-62-9 | C5H7NO4 | 1 mg |
- (2S)-2-Hydroxyglutaric Acid
Potential inhibitor of glutamate carboxypeptidase.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-311696 | 13095-48-2 | C5H8O5 | 25 mg |
- (2S)-α-Ethylglutamic acid
Group II mGluR antagonist| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-220848 | n.n. | C7H13NO4 | 1 mg |
- (+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid
Displays NMDA antagonistic activity.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-288641 | 100828-16-8 | C8H17N2O5P | 10 mg |
- 3-MATIDA
Potent metabotropic glutamate mGlu1 receptor antagonist (IC50 = 6.3 μM at rat mGlu1a).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203470 | 518357-51-2 | C8H9NO4S•xH20 | 10 mg/50 mg |
- 5,7-Dichlorokynurenic acid
A potent antagonist at the NMDA receptor glycine modulatory site. Noncompetitively antagonizes NMDA-stimulated responses.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200440 | 131123-76-7 | C10H5Cl2NO3 | 10 mg/50 mg |
- 5,7-Dichlorokynurenic acid sodium salt
A sodium salt of 5,7-Dichlorokynurenic acid (sc-200440). Acts as a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine). | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-291018 | 131123-76-7 (non-salt) | C10H4Cl2NNaO3 | 10 mg/50 mg |
- 6,7-Dinitroquinoxaline-2,3-dione (DNQX)
A non-NMDA receptor complex antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200444 | 2379-57-9 | C8H4N4O6 | 10 mg/50 mg |
- 7-Chlorokynurenic acid
NMDA receptor antagonist acting at the glycine site.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358717 | 18000-24-3 | C10H6CINO3 | 10 mg/50 mg |
- 7-Chlorokynurenic acid sodium salt
Sodium salt of 7-Chlorokynurenic acid (sc-202893), an NMDA receptor antagonist acting at the glycine site. Acts as a potent competitive inhibitor of L-glutamate transport into synaptic vesicles.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-291578 | n.n. | C10H5CINNaO3 | 10 mg/50 mg |
- 7-Chlorothiokynurenic acid hydrochloride
NMDA receptor antagonist acting at the glycine site. More potent than the corresponding kynurenic acid analog.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202430 | 135025-56-8 | C10H6ClNO2S ·HCl | 5 mg |
- A 841720
Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analgesic effects; decreases mechanical allodynia in models of neuropathic pain;impairs cognitive function| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203792 | 869802-58-4 | C17H21N5OS | 10 mg/50 mg |
- ACBC
NMDA receptor antagonist acting at the glycine site.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203493 | 22264-50-2 | C5H9NO2 | 25 mg |
- ACDPP hydrochloride
Antagonist at the mGlu5 receptor (Ki = 295 nM). Inhibits human mGlu5 receptor-mediated calcium flux with an IC50 of 134 nM.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203494 | 37804-11-8 | C12H13ClN6O•HCl•xH20 | 10 mg/50 mg |
- ACET
Potent and selective GluR5-containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA recptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203801 | n.n. | C20H19N3O6S | 10 mg |
- AIDA
A selective antagonist of the mGluR1. Competitively antagonizes the stimulatory response of glutamate at mGluR1a.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202047 | 168560-79-0 | C11H11NO4 | 5 mg |
- (+/-)-alpha-Amino-3-hydroxy-5-methylisoxazole- 4-propionic Acid Hydrobromide
Shows highly potent agonist activity towards central glutamate/quisqualate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-291862 | 118896-96-1 | C7H10N2O4 ·HBr | 1 mg/5 mg |
- α-Benzylquisqualic acid
Selective antagonist of group II mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-221178 | n.n. | C12H13N3O5 | 1 mg/5 mg |
- α-Ketoglutaric acid sodium salt
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-214449 | 22202-68-2 | C5H5NaO5 | 1 g/5 g |
- AMN082 Dihydrochloride
Potent and selective agonist at mGluR7 acting at an allosteric site.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200483 | 83027-13-8 | C28H28N2 ·2HCl | 10 mg/50 mg |
- AMPA
A potent agonist of the AMPA receptor, a glutamate-recognizing ionotropic receptor. Agonism of the AMPA receptor produces neuronal excitation.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200437 | 74341-63-2 | C7H10N2O4 | 5 mg/50 mg |
- Aniracetam
Nootropic with modulatory actions through allosteric potentiation of reduction of glutamate receptor desensitization, AMPA specific receptors, and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203514 | 72432-10-1 | C12H13NO3 | 50 mg/250 mg |
- Arcaine sulfate
Arcaine is a novel and potent antagonist of the polyamine site on the NMDA receptor. it can inhibit [3H]MK801 binding in the absence of added polyamines.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200475 | 14923-17-2 | C6H16N6 ·H2SO4 | 20 mg/50 mg |
- BINA
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361121 | 866823-73-6 | C30H30O4 | 10 mg/50 mg |
- Boc-L-Glutamic acid 5-fluorenyl methyl ester
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-285175 | 123417-18-5 | C24H27NO6 | 1 g/5 g |
- CBiPES hydrochloride
Positive allosteric modulator of the mGlu2 receptor| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358830 | 856702-40-4 | C21H19N3O2S•HCl | 10 mg/50 mg |
- CCMQ
Acts selectively when inhibiting homoquinolinic acid binding to non-NMDA sensitive sites. Works in combination with [3H]-homoquinolinic acid to characterize NR2B-containing NMDA receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205625 | n.n. | C12H9NO4 | 10 mg/50 mg |
- CFM-2
A novel, selective, non-competitive AMPA antagonist1.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203429 | 178616-26-7 | C17H17N3O3 | 10 mg |
- CGP 37849
Potent, competitive and selective NMDA antagonist. Orally active anticonvulsive.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203880 | 127910-31-0 | C6H12NO5P | 10 mg/50 mg |
- CGP 39551
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361139 | 127910-32-1 | C8H16NO5P | 10 mg/50 mg |
- CGP 78608 hydrochloride
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361144 | 206648-13-7 | C11H13BrN3O5P.HCl | 10 mg/50 mg |
- CGS 19755
Potent, competitive NMDA antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203882 | 110347-85-8 | C7H14NO5P | 10 mg/50 mg |
- Chicago Sky Blue 6B
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361146 | 2610-05-1 | C34H24N6Na4O16S4 | 25 g |
- CHPG
A selective metabotropic glutamate receptor agonist, mGlu5. Inactive at mGlu1a receptors which are expressed in CHO cells. Active in vivo.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205931 | 170846-74-9 | C8H8NO3Cl | 10 mg/50 mg |
- CHPG Sodium salt
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361148 | n.n. | C8H7ClNO3 ·Na | 10 mg/50 mg |
- cis-(+/-)-3,4-Dichloro-N-Methyl-N-(2-[1-Pyrrolidinyl]Cyclo- Hexyl)Benzeneacetamide Hydrochloride
Shown to be a potent antagonist of NMDA and displays anticonvulsant effects.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-294036 | 92953-41-8 | C18H24Cl2N2O | 1 mg/5 mg |
- cis-1,3-homo-ACPD
An equimolar mixture of (1R,3R)-homo-ACPD and (1S,3S)-homo-ACPD. This compound is a selective agonist for group II mGluRs and has no effect at ionotropic excitatory amino acid receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205932 | n.n. | C8H13NO4 | 5 mg |
- cis-ACPD
Potent NMDA agonist. Equimolar mixture of (1R,3R)-ACPD| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202102 | 39026-63-6 | C7H11NO4 | 5 mg |
- Cl-HIBO
Highly desensitising AMPA receptor agonist. Subtype selective for GluR1 and GluR2 subunit-containing receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205934 | n.n. | C6H7ClN2O4 | 10 mg/50 mg |
- CNQX disodium salt
Water soluble, potent competitive kainate/quisqualate (non-NMDA) receptor antagonist. More soluble form of CNQX| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203003 | 115066-14-3 (non-salt) | C9H2N4O4Na2 | 5 mg/10 mg |
- Co 101244 hydrochloride
Highly selective N-methyl-D-aspartate (NMDA) NR2B subtype antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203899 | 193359-26-1 | C21H27NO3 ·HCl | 10 mg/50 mg |
- CP 465022 hydrochloride
AMPA antagonist which is selective, non-competitive and displays anti-convulsant activity.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205272 | 199655-36-2 | C26H24ClFN4O ·HCl | 10 mg/50 mg |
- CPCCOEt
The compound CPCCOEt is a reversible and non-competitive antagonist of type 1α metabotropic glutamate receptor activation.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200481 | 179067-99-3 | C13H13NO4 | 5 mg/25 mg |
- CX546
AMPA receptor potentiator which is specifically bound to agonist bound non-desensitized receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205278 | 215923-54-9 | C14H17NO3 | 10 mg/50 mg |
- D-AP3
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-211171 | 128241-72-5 | C3H8NO5P | 5 mg |
- D-AP7
More active form of DL-AP7| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203016 | 81338-23-0 | C7H16NO5P | 5 mg |
- D-Aspartic acid
Endogenous NMDA receptor agonist with similar activity to the L-isomer. Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202562 | 1783-96-6 | C4H7NO4 | 1 g |
- D-CPP-ene
Potent, competitive N-methyl-D-aspartic acid (NMDA) antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203910 | 117414-74-1 | C8H15N2O5P | 10 mg |
- D-Cycloserine
Reported to improve memory-dependent tasks in rats. Partial agonist of NMDA receptors at the glycine modulatory site. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-221470 | 68-41-7 | C3H6N2O2 | 200 mg/1 g |
- D-Quisqualic acid
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358857 | 52809-07-1 (L-isomer) | C5H7N3O5 | 10 mg |
- D(-)-2-Amino-4-phosphonobutanoic acid (D-AP4)
NMDA antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200429 | 78739-01-2 | C4H8NO5P-2 | 5 mg |
- D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)
A selective antagonist of the NMDA receptors. Antagonizes amino acid- and electrically-induced synaptic excitations. Protects neurons against oxidative damage, increasing levels of SOD, catalase, and GSH.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200434 | 79055-68-8 | C5H12NO5P | 5 mg |
- DCB
Allosteric ligand for the metabotropic glutamate receptor mGlu5; displays neutral modulation. Does not affect agonist-stimulated mGlu5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB and DMeOB.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203560 | 6971-97-7 | C14H10Cl2N2 | 10 mg/50 mg |
- Desmethyl-YM 298198
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361167 | 299901-57-8 | C17H20N4OS.HCl | 10 mg/50 mg |
- Dextromethorphan Hydrobromide
An NMDA receptor agonist that is the d-form of racemethorphan, where it is widely used as a cough suppressant. Newer uses include its anticonvulsive and neuro-protective properties. It was also found to improve cerebral ischemia.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204716 | 125-69-9 | C18H25NO ·HBr | 5 g/10 g |
- DFB
Selective allosteric potentiator of metabotropic glutamate receptor subtype 5 (mGlu5).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203918 | 15332-10-2 | C14H10F2N2 | 10 mg/50 mg |
- DL-2-Amino-3-phosphonopropionic acid (AP3)
An inhibitor of phosphoserine phosphatase and antagonist of mGluR, blocking mGluR-mediated phosphoinositide turnover. D-AP3 produces phosphoserine phosphatase inhibition and L-AP3 both antagonizes mGluR and inhibits phosphoserine phosphatase with similar potency.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200433 | 20263-06-3 | C3H8NO5P | 50 mg |
- DL-2-Amino-5-phosphonovaleric acid (AP5)
Shown to be a potent and selective NMDA antagonist which causes antagonism of synaptic and amino-acid induced excitation in nerves.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-201503 | 76326-31-3 | C5H12NO5P | 10 mg/50 mg |
- DL-2-Aminoadipic acid
An excitatory amino acid analogue, which functions as a glutamine synthetase inhibitor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-255121 | 542-32-5 | C6H11NO4 | 1 g/5 g |
- DL-AP7
A competitive antagonist of the ionotropic glutamate receptor, NMDA.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203028 | 78966-69-5 | C7H16NO5P | 5 mg |
- DMEOB
Negative allosteric modulator at mGlu5. Exhibits reversible non-competitive inhibition of mGlu5-mediated responses.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203569 | 40252-74-2 | C16H16N2O2 | 10 mg/50 mg |
- Domoic acid
An analogue of the neurotransmitter glutamate and an effective excitatory neurotransmitter that activates kainate subtype glutamate receptors| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200446 | 14277-97-5 | C15H21NO6 | 1 mg/5 mg |
- E4CPG
Group I/group II metabotropic glutamate receptor antagonist which is more potent than (RS)-MCPG.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205943 | n.n. | C11H13NO4 | 10 mg/50 mg |
- EGLU
Selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord. Assumed to be a group II mGlu receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205944 | n.n. | C7H13NO4 | 10 mg/50 mg |
- Eliprodil
Non-competitive NR2B-selective NMDA antagonist. Noncardiac drug with neuroprotective properties.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203939 | 119431-25-3 | C20H23ClFNO | 10 mg/50 mg |
- Felbamate
Anticonvulsant, acting as an antagonist at the NMDA-associated glycine binding site.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203579 | 25451-15-4 | C11H14N2O4 | 10 mg/50 mg |
- Fenobam
A selective non-competitive antagonist of the mGluR-5 receptor. Produces inverse agonist activity through an allosteric modulatory site. Demonstrates anxiolytic effects.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202608 | 57653-26-6 | C11H11ClN4O2 | 5 mg/25 mg |
- gamma-D-Glutamylaminomethylsulfonic acid
This product is a selective antagonist of kainate/quisqualate.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-295005 | 90237-02-8 | C6H12N2O6S | 1 mg/5 mg |
- γDGG
Broad spectrum glutamate receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203728 | 6729-55-1 | C7H12N2O5 | 50 mg |
- Gavestinel
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361183 | 153436-22-7 | C18H11Cl2N2O3Na | 10 mg/50 mg |
- GYKI 47261 dihydrochloride
Non-competitive AMPA antagonist receptor (IC50 = 2.5 μM). In vivo, displays broad spectrum anticonvulsive activity and neuroprotective effects.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203993 | 220445-20-5 | C18H15ClN4 ·2HCl ·xH2O | 10 mg/50 mg |
- GYKI 52466 dihydrochloride
Selective non-competitive allosteric AMPA receptor antagonist. Anticonvulsant; skeletal muscle relaxant. Exhibits anti-proliferative effects in transformed cells.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203591 | 102771-26-6 | C17H15N3O2•2HCl•xH2O | 10 mg/50 mg |
- HexylHIBO
Group I mGlu antagonist (receptor). In vitro, decreases sEPSCs in rat pyramidal neurons.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203597 | 334887-43-3 | C12H20N2O4 | 10 mg/50 mg |
- (±)-HIP-A
Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC50 = 1.6 μM) rather than [3H]L-glutamate uptake (IC50 = 18 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 43 and 8 μM respectively).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203598 | 227619-64-9 | C6H8N2O4 | 10 mg |
- HIP-B
Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [3H]D-aspartate release (IC550= 1.2 μM) rather than [3H]L-glutamate uptake (IC50 = 16.9 μM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 35 and 45 μM respectively).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203599 | 227619-65-0 | C6H8N2O4 | 10 mg |
- HomoAMPA
Higher homologue of AMPA. Compound is completely inactive at ionotropic glutamate receptors but instead is a relatively potent and highly mGlu6 subtype selective metabotropic glutamate receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204001 | n.n. | C8H12N2O4 | 10 mg/50 mg |
- Homoquinolinic acid
An analog of glutamic acid shown to excite rat cortical neurons and also be a neurotoxic agent. Found to specifically target the NR2A/B subunit of NMDA.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200456 | 490-75-5 | C8H7NO4 | 5 mg/25 mg |
- Ibotenic acid
A conformationally restricted analogue of glutamic acid which is a useful tool in morphological and functional analysis of central neuronal systems in vivo and in vitro.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200449 | 2552-55-8 | C5H6N2O4 | 1 mg/5 mg |
- Ibotenic acid monohydrate
A hydrate of Ibotenic acid and a conformationally restricted analogue of glutamic acid which is a useful tool in morphological and functional analysis of central neuronal systems in vivo and in vitro.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-295172 | 60573-88-8 | n.n. | 1 mg/5 mg |
- IEM 1460
Adamantane derivative. Open-channel blocker of AMPA currents; selectively blocks GluR2-lacking, Ca2+-permeable AMPA receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204007 | 121034-89-7 | C19H37N2Br•HBr | 10 mg/50 mg |
- IEM 1754 dihydrobromide
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362747 | C16H30N2.2HBr | 162831-31-4 | 10 mg/50 mg |
- IEM 1925 dihydrobromide
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362748 | 258282-23-4 | C17H28N2.2HBr | 10 mg/50 mg |
- Ifenprodil Tartrate Salt
Shown to be a NMDA receptor antagonist, believed to act at the polyamine site. A neuroprotective agent, an alpha-adrenergic central and peripheral vasodilator, and an alpha ligand.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-295173 | 23210-56-2 | C21H27NO2 | 5 mg/10 mg |
- Ifenprodil hemitartrate
NMDA receptor antagonist, acting at the polyamine site. Also an α-adrenergic vasodilator. σ2 ligand displaying about 3-fold selectivity over σ 1 sites.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203601 | 23210-58-4 | (C21H27NO2)2 ·C4H6O6 | 10 mg/50 mg |
- Ivermectin
Positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Also modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203609 | 70288-86-7 | C48H74O14 ·(B1a ·form) | 100 mg/1 g |
- JNJ 16259685
Sub-nanomolar potent, non-competitive mGlu1 antagonist. Inhibits glutamate-induced Ca2+ response at the human mGluR1. Selective over mGluR5. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202670 | 409345-29-5 | C20H23NO3 | 5 mg/25 mg |
- Joro Spider Toxin
Originally isolated from the spider Nephila clavata, shown to selectively block postsynaptic glutamate potentials and quisqualate-sensitive glutamate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200453 | 112163-33-4 | C27H47N7O6 | 100 µg |
- Kynurenic acid
A potential ligand of GPR35 G-protein-coupled receptor, antagonist of excitatory amino acids (EAA) and N-methyl-D-aspartate (NMDA) receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202683 | 492-27-3 | C10H7NO3 | 250 mg/1 g |
- Kynurenic acid sodium salt
A sodium salt of Kynurenic acid. A potential ligand of GPR35 G-protein-coupled receptor, antagonist of excitatory amino acids (EAA) and N-methyl-D-aspartate (NDMA) receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358835 | 492-27-3 (non-salt) | C10H6NO3•Na | 100 mg |
- L-(-)-threo-3-Hydroxyaspartic acid
Potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204033 | 7298-99-9 | C4H7NO5 | 10 mg |
- L-689,560
A selective antagonist at the glycine-binding site of the NMDA receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202684 | 139051-78-8 | C17H15N3O3Cl2 | 1 mg |
- L-701,252
NMDA receptor antagonist acting at the glycine site1. Anticonvulsant.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205726 | 151057-13-5 | C13H10ClNO3 | 10 mg/50 mg |
- L-701,324
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361224 | 142326-59-8 | C21H14CINO3 | 10 mg/50 mg |
- L-AP3
Selective antagonist of the PI-linked metabotropic glutamate response.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202201 | 23052-80-4 | C3H8NO5P | 5 mg/25 mg |
- L-AP6
QUIS-sensitized L-AP4 receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202202 | 78944-89-5 | C6H14NO5P | 5 mg/1 mg |
- L-BMAA hydrochloride
Monocarboxylic, neurotoxic amino acid; can act at the strychnine-insensitive glycine modulatory site to modify the activity of N-methyl-D-aspartate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204049 | 15920-93-1 | C4H10N2O2.HCl | 10 mg |
- L-CCG-I
Potent group II mGluR agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203097 | 117857-93-9 | C6H9NO4 | 1 mg |
- L-CCG-IV
Potent NMDA receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203098 | 117857-95-1 | C6H9NO4 | 1 mg |
- L-Cysteinesulfinic acid
An amino acid neurotransmitter.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203620 | 1115-65-7 | C3H7NO4S | 100 mg |
- L-Glutamic acid γ-(α-naphthylamide) monohydrate
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-215217 | 81012-91-1 | C15H16N2O3⋅H2O | 25 mg/1 g |
- L-Glutamic acid γ-(β-naphthylamide)
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-215219 | 14525-44-1 | C15H16N2O3 | 100 mg/1 g |
- L-Glutamic acid γ-(3-carboxy-4-hydroxyanilide)
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-215215 | 74929-17-2 | C12H14N2O6 | 10 mg/250 mg |
- L-Pyroglutamic acid 4-nitroanilide
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-211711 | 66642-35-1 | C11H11N3O4 | 25 mg |
- L-Quisqualic acid
Quisqualate acts as an agonist for metabotropic glutamate receptor 1 (mGluR1), and can be used to differentiate between mGluR1 and mGluR4.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200467 | 52809-07-1 | C5H7N3O5 | 5 mg/25 mg |
- L-trans-Pyrrolidine-2,4-dicarboxylic acid
An inhibitior of glutamate transport. Demonstrates an increase in extracellular glutamate levels, leading to massive NMDAR-mediated neuronal death with no observed agonism of NMDAR.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200477 | 64769-66-0 | C6H9NO4 | 5 mg/25 mg |
- L(+)-2-Amino-4-phosphonobutanoic acid (L-AP4)
An amino-acid derivative and a mGluR4 and mGluR6 metabotropic glutamate receptor agonist. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200432 | 23052-81-5 | C4H10NO5P | 5 mg |
- L(+)-2-Amino-5-phosphonovaleric acid
This product has been shown to be an NMDA antagonist. It has also been oberved to be an agonist at quisqualate-sensitized AP6 site, where it is more potent than the D-isomer. There is evidence that L-AP5 can preferentially block cone signals in the rat retina.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358599 | 79055-67-7 | C5H12NO5P | 5 mg/50 mg |
- Lamotrigine isethionate
A water soluble phenyltriazine compound, which functions as an inhibitor of voltage gated sodium channels of presynaptic neurons.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-218654 | 113170-86-8 | C9H7Cl2N5.C2H6O4S | 10 mg |
- LY 233053
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361238 | 125546-04-5 | C8H13N5O2 | 1 mg/10 mg |
- LY 235959
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361239 | 137433-06-8 | C11H20NO5P | 10 mg/50 mg |
- LY 341495
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361244 | 201943-63-7 | C20H19NO5 | 1 mg/10 mg |
- LY 341495 disodium salt
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362765 | n.n. | C20H17NNa2O5 | 1 mg/10 mg |
- LY 354740
This compound is a highly selective and potent group II (mGlu 2/3) receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204064 | 176199-48-7 | C8H11NO4 | 10 mg/50 mg |
- LY 367385
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361246 | 198419-91-9 | C10H11NO4 | 10 mg/50 mg |
- LY 379268
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361247 | 191471-52-0 | C7H9NO5 | 10 mg/50 mg |
- LY 395756
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-359013 | 842679-66-4 | C9H13NO4 | 10 mg/50 mg |
- LY 456236 hydrochloride
Selective mGlu1 antagonist. Reduces formalin-induced hyperalgesic behavior in both mouse and rat with ED50 values of 28 and 16.3 mg/kg, respectively.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203625 | 338738-57-1 | C16H15N3O2.HCl | 10 mg/50 mg |
- LY 487379 hydrochloride
Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204065 | 353231-17-1 | C21H19F3N2O4S ·HCl | 10 mg/50 mg |
- MAP4
Selective agonist for group III mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202221 | 157381-42-5 | C5H12NO5P | 5 mg |
- Matrine
An alkaloid. Has antiulcerogenic activity against stress ulcer in rat. It depresses both glutamate-induced responses and neurally evoked excitatory junctional potentials.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205741 | 519-02-8 | C15H24N2O | 100 mg/500 mg |
- Memantine hydrochloride
An antagonist at the NMDA receptor, binding to the ion channel site. Used in the treatment of Parkinsonism.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203628 | 41100-52-1 | C12H21N ·HCl | 50 mg |
- mGluR5 Ligand, CDPPB
A pyrazole amide compound that crosses the blood-brain barrier and acts as a potent, selective, reversible, positive allosteric modulator for metabotropic glutamate receptor subtype 5 (mGluR5). This also exerts anti-psychotic-like effects. It is reported to potentiate the response to glutamate (~300 nM) in CHO-mGluR5 cells (EC50 = 10 nM for human, 4-fold potentiation; 20 nM for rat, 4.3-fold potentiation) and reverse amphetamine-induced disruption of pre-pulse inhibition (PPI) in rats. The specificity was determined using a panel of kinases and receptors. It does not potentiate the activity of other glutamate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-221942 | 781652-57-1 | C23H16N4O | 1 mg |
- (-)-MK 801 maleate
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361253 | 77086-19-2 | C16H15N.C4H4O4 | 10 mg/50 mg |
- (+)-MK 801 Maleate
A selective non-competitive antagonist of the NMDA receptor. Interacts with NMDA-associated ion channel, blocking Ca2+ flux and NMDA-induced depolarization. Demonstrates neuroprotective effects.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203137 | 77086-22-7 | C16H15N•C4H4O4 | 10 mg |
- MMPIP hydrochloride
Potent allosteric mGlu7-selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC50 = 15 nM), indicating inverse agonist activity.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204093 | 479077-02-6 | C19H15N3O3 ·HCl | 1 mg/10 mg |
- MNI caged kainic acid
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-359014 | 487-79-6 (uncaged) | C19H23N3O6 | 10 mg |
- MNI-caged-L-glutamate
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361257 | 295325-62-1 | C14H17N3O6 | 10 mg/50 mg |
- MNI-caged-NMDA
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361258 | n.n. | C14H17N3O6 | 10 mg |
- MPDC
A strong inhibitor of the Na+-dependent high-affinity synaptosomal glutamate transporter.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204097 | n.n. | C7H9NO4 | 10 mg |
- MPPG
Potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons. Antagonist of mGlu receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203143 | 169209-65-8 | C9H12NO5P | 10 mg/50 mg |
- MSOP
Selective group III metabotropic glutamate receptor antagonist. Displays an apparent Kd of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Has no activity on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203637 | 66515-29-5 | C4H10NO6P | 10 mg/50 mg |
- MTEP
A brain-permeable (thiazole-pyridine)alkyne compound that acts as a potent, selective and non-competitive mGluR5 antagonist with in vivo anxiolytic activity in a rodent model. Highly selective and potent with a 5-fold higher anxiolytic activity than MPEP. Shows fewer off-target effects than MPEP.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205956 | n.n. | C11H8N2S | 5 mg/25 g |
- MTEP hydrochloride
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361267 | n.n. | C11H8N2S.HCl | 10 mg/50 mg |
- MTPG
Group II/group III mGlu antagonist, showing selectivity for group II in electrophysiological studies. Potent antagonist for (1S,3S)-ACPD-sensitive receptors; preference for GluR2 and GluR3 subtypes.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204106 | 169209-66-9 | C10H11N5O2 | 10 mg/50 mg |
- N-(3-Aminopropyl)cyclohexylamine
An inhibitor of spermine synthase. Described to specifically deplete spermidine and spermine levels in cultured rat hepatoma cells. Anatagonizes the facilitating effect of spermidine on NMDLA-induced seizures.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202715 | 3312-60-5 | C9H20N2 | 1 g |
- N-(4-Hydroxyphenylacetyl)-spermine
A wasp toxin analog of naturally occurring PhTX-433. This is a very potent glutamate antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200466 | 130210-32-1 | C18H32N4O2 | 250 µg |
- N-(4-Hydroxyphenylpropanoyl) spermine trihydrochloride
Wasp toxin analog. More potent than PhTX-343 at locust NMJ. Antagonist of the quisqualate-sensitive L-glutamate receptor (quis-GluR) of locust muscle.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204109 | 130631-59-3 | C19H34N4O2 ·3HCl | 250 µg |
- N-Acetyl-Asp-Glu-OH
Endogenous neurotransmitter with high affinity for the brain glutamate receptor. mGluR3 activator. NMDA receptor antagonist. Neuroprotective.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202717 | 3106-85-2 | C11H16N2O8 | 10 mg/50 mg |
- N-Acetylglycyl-D-glutamic acid
Excitatory peptide, more potent than L-glutamic acid at inducing seizures in mice. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204111 | 135701-69-8 | C9N14N2O6 | 10 mg/50 mg |
- N-Glutaryl-Gly-Phe-4-methoxy-β-naphthylamide
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-215459 | 100940-58-7 | C27H29N3O6 | 10 mg/25 mg |
- N-Glutaryl-L-phenylalanine p-nitroanilide
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-215460 | 5800-34-0 | C20H21N3O6 | 1 g/5 g |
- N20C hydrochloride
Non-competitive NMDA receptor open-channel blocker. Binds to receptor-associated ion channels and prevents glutamate-induced Ca2+ influx. Displays neuroprotective activity in vivo, and reportedly to be a brain-penetrant.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204116 | 76991-05-4 | C17H20N2O•HCl | 10 mg/50 mg |
- Neuronal Differentiation Inducer III
A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation in various stem/progenitor cells.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222058 | n.n. | C11H10N2O2S | 10 mg |
- NPEC-caged-(1S,3R)-ACPD
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-359016 | n.n. | C16H18N2O8 | 10 mg/50 mg |
- NPEC-caged-(S)-3,4-DCPG
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-359017 | n.n. | C19H16N2O10 | 10 mg/50 mg |
- NPEC-caged-(S)-AMPA
Caged compound; a 1-(2-nitrophenyl)ethyl caged version of (S)-AMPA agonist at the AMPA receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358838 | n.n. | C16H17N3O8 | 10 mg |
- NPEC-caged-D-AP5
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362772 | n.n. | C14H19N2O9P | 10 mg/50 mg |
- NPEC-caged-LY 379268
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-359019 | n.n. | C16H16N2O9 | 10 mg |
- NS 3763
Selective non-competitive kainate receptor antagonist; displays selectivity for GLUK5 subunit-containing receptors (IC50 values are 1.6 and > 30 mM for homomeric GLUK5 and GLUK6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC50 >> 30 mM).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203651 | 70553-45-6 | C22H16N2O6 | 10 mg/50 mg |
- O-Phospho-L-serine
L-AP4 agonist. Competitive NMDA antagonist. Has affinity for type IV, but not type I, metabotropic glutamate receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202257 | 407-41-0 | C3H8NO6P | 1 g |
- PCCG-13
A potent, selective and competitive antagonist of PLD-coupled mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205962 | n.n. | C12H13NO4 | 1 mg |
- PCCG-4
Selective group II mGluR antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222130 | n.n. | C12H13NO4 | 1 mg/5 mg |
- Pentamidine isethionate
Exhibits inhibitory actions on constitutive nitric oxide synthase in the brain and acts as a NMDA Glu antagonist. Antimicrobial, neuroprotective agent.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204176 | 140-64-7 | C19H24N4O2•2C2H6O4S | 50 mg |
- PEPA
Allosteric potentiator of AMPA desensitization. Decreases rate of onset of desensitization and potentiates steady-state equilibrium currents induced by Glu with splic variant and subunit selectivity. Enhances post-ischemic memory impairment in rats post i.v. administration.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204178 | 141286-78-4 | C16H16F2N2O4S2 | 10 mg/50 mg |
- PHCCC
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361292 | n.n. | C17H14N2O3 | 10 mg/50 mg |
- Philanthotoxin 74
Subtype-selective AMPA receptor antagonist that inhibits GluR1/2 but not GluR2/3 receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204189 | 401601-12-5 | C24H42N4O3 ·2HCl | 1 mg/10 mg |
- Piracetam
Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux. Through AMPA receptors, potentiates Na+ influx. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204196 | 7491-74-9 | C6H10N2O2 | 5 g/25 g |
- PMPA (NMDA antagonist)
Short-chain competitive NMDA antagonist. Displays Ki values of 0.84, 2.74, 3.53 and 4.16 μM at NR2A, NR2B, NR2C and NR2D subunit-containing receptors respectively. Selective over AMPA receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204850 | 113919-36-1 | C6H13N2O5P | 10 mg/50 mg |
- PPDA
Subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors (Ki values are 0.096, 0.125, 0.31 and 0.55 μM for NR2C, NR2D, NR2B and NR2A subunits respectively).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204210 | n.n. | C21H18N2O5 ·xH2O | 10 mg/50 mg |
- PPPA
Competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors (Ki values are 0.13, 0.47, 1.10 and 3.86 μM for NR2A, NR2B, NR2C and NR2D subunits respectively).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204212 | n.n. | C9H18NO5P | 10 mg/50 mg |
- Putrescine dihydrochloride
A compound that binds to the polyamine modulatory site of the NMDA (N-methyl D-aspartate) receptor and potentiate NMDA-induced currents. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202786 | 333-93-7 | C4H12N2 ·2HCl | 1 g |
- Quinolinic acid
Metabolite of tryptophan. Putative NMDA receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203226 | 89-00-9 | C7H5NO4 | 1 g |
- (R,S)-ATPA
Potent and selective agonist of the GluR5 subtype of the kainate receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203232 | 140158-50-5 | C10H16N2O4 | 1 mg/5 mg |
- (R)-(+)-HA-966
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361303 | 123931-04-4 | C4H8N2O2 | 10 mg/50 mg |
- (R)-3-Carboxy-4-hydroxyphenylglycine
Moderately potent NMDA and AMPA/kainate receptor antagonist. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204871 | 13861-03-5 | C9H9NO5 | 10 mg/50 mg |
- (R)-3,4-DCPG
AMPA receptor antagonist with little activity at kainate receptors and weak activity at NMDA receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204227 | n.n. | C10H9NO6 | 10 mg/50 mg |
- (R)-4-Carboxyphenylglycine
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361304 | 134052-68-9 | C9H9NO4 | 10 mg/50 mg |
- (R)-AMPA
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361305 | 83654-13-1 | C7H10N2O4 | 10 mg |
- (R)-CPP
Highly potent NMDA receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202308 | 126453-07-4 | C8H17N2O5P | 1 mg/10 mg |
- Remacemide hydrochloride
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361307 | 111686-79-4 | C17H20N2O.HCl | 10 mg/50 mg |
- Ro 01-6128
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362789 | 302841-86-7 | C17H17NO3 | 10 mg/50 mg |
- Ro 04-5595 hydrochloride
Selective antagonist for NR2B-containing NMDA receptors. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204885 | 194089-07-1 | C19H22ClNO2.HCl | 10 mg/50 mg |
- Ro 25-6981 maleate
NMDA agonist. Potent and selective activity-dependent blocker NR2B subunit-containing NMDA receptors . IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Acts as a neuroprotectant in vivo and in vitro. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204887 | 169274-78-6 | C22H29NO2 ·C4H4O4 | 1 mg/10 mg/50 mg |
- Ro 67-4853
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362790 | 302841-89-0 | C19H19NO4 | 10 mg/50 mg |
- Ro 8-4304 Hydrochloride
NMDA receptor antagonist (IC50 = 0.4 μM) that displays > 100 fold selectivity for NR2B-containing receptors over NR2A-containing receptors. Displays an activity-dependent mechanism of NMDA antagonism and is competitive with respect to spermine.
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204241 | 195988-65-9 | C21H23FN2O3 ·HCl | 10 mg/50 mg |
- (RS)-(Tetrazol-5-yl)glycine
Highly potent NMDA receptor agonist
Potent NMDA receptor agonist, approximately 20 times more active than NMDA. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205495 | 138199-51-6 | C3H5N5O2 | 10 mg/50 mg |
- (RS)-α-Methyl-3-carboxy-4-hydroxyphenylglycine
This is a potent antagonist of both L-AP4 and L-CCG-I-induced depressions of forskolin-stimulated cAMP production. It shows preferential antagonist activity versus L-CCG-I. Group I/group II mGluR antagonist at cloned receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222264 | n.n. | C10H11NO5 | 5 mg |
- (RS)-3-Hydroxyphenylglycine
Agonist at PI-linked metabotropic glutamate receptors. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204246 | 31932-87-3 | C8H9NO3 | 10 mg/50 mg |
- (RS)-3,4-DCPG
Systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG (mGlu8-selective agonist) or (R)-3,4,-DCPG (AMPA/NMDA antagonist).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204247 | n.n. | C10H9NO6 | 10 mg/50 mg |
- (RS)-3,5-DHPG
Selective group I metabotropic glutamate receptor agonist which activates both mGlu1 and mGlu5.Reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205496 | 19641-83-9 | C8H9NO4 | 10 mg/50 mg |
- (RS)-4-Bromo-homo-ibotenic acid
Potent AMPA receptor agonist. Selective but relatively non-potent group I mGluR agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203244 | 71366-32-0 | C6H7N2O4Br | 5 mg |
- (RS)-4-Carboxyphenylglycine
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361319 | 7292-81-1 | C9H9NO4 | 10 mg/50 mg |
- (RS)-4C3H-PG
'Broad spectrum' EAA ligand| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203245 | 134052-66-7 | C9H9NO5 | 10 mg/50 mg |
- (RS)-AMPA hydrobromide
More water soluble form of sc-200437.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203246 | 77521-29-0 | C7H10N2O4 ·HBr | 1 mg |
- (RS)-APICA
A rigidified analog of MPPG; a selective group II metabotropic glutamate receptor antagonist (IC50 = 30 μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses an unusual inverse agonist-like action.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204248 | n.n. | C10H12NO5P | 10 mg/50 mg |
- (RS)-CPPG
Most potent group II/III mGluR antagonist, with approx. 20-fold selectivity for group III over group II.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203448 | 183364-82-1 | C11H14NO5P | 5 mg/25 mg |
- (RS)-MCPG
A non-selective antagonist of group I/II mGluRs. Used as a tool for probing the mGluR system.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202325 | 146669-29-6 | C10H11NO4 | 5 mg |
- (RS)-MCPG disodium salt
A non-selective group I/group II metabotropic glutamate receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358840 | n.n. | C10H9NNa2O4 | 10 mg |
- (RS)-MSPG
A non-selective antagonist of mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203247 | 169209-64-7 | C9H11NO5S | 10 mg |
- (RS)-PPG
Potent and selective group III mGluR agonist, with a subtype specificity towards the mGlu3 receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202797 | 120667-15-4 | C8H10NO5P | 5 mg |
- S-(+)-CBPG
This is a potent and selective, structurally new group I mGluR antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222268 | n.n. | C8H11NO4 | 1 mg/5 mg |
- S-(N,N-Diethylcarbamoyl)glutathione
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-220012 | 157723-51-8 | C15H26N4O7S | 5 mg |
- S-(N,N-Diethylcarbamoyl)glutathione Sulfoxide
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-220013 | n.n. | C14H26N4O8S | 5 mg |
- S-Sulfo-L-cysteine sodium salt
EAA receptor agonist. Agonist at mGlu1α and mGlu5a subtypes expressed in clonal RGT cell lines. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205498 | 1637-71-4 | C3H6NO5S2Na.xH2O | 10 mg/50 mg |
- (S)-(-)-5-Fluorowillardiine
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361326 | 140187-23-1 | C7H8FN3O4 | 10 mg/50 mg |
- (S)-(-)-5-Iodowillardiine
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361327 | 140187-25-3 | C7H8IN3O4 | 10 mg/50 mg |
- (S)-3-Carboxy-4-hydroxyphenylglycine
Mixed group II mGlu agonist and group I metabotropic glutamate receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203689 | 55136-48-6 | C9H9NO5 | 10 mg/50 mg |
- (S)-3-Hydroxyphenylglycine
Agonist at group I metabotropic glutamate receptors (mGlu1) having no effect at mGlu2 or mGlu4.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204254 | 71301-82-1 | C8H9NO3 | 10 mg/50 mg |
- (S)-3,4-DCPG
Potent, selective mGlu8a agonist (EC50 = 31 nM). Displays > 100-fold selectivity over mGlu1-7 and displays little/no activity at NMDA and kainate receptors. Increases c-Fos expression in stress-related brain areas following systemic administration in mice in vivo. Also a potent anticonvulsant in mice in vivo.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204255 | 201730-11-2 | C10H9NO6 | 10 mg/50 mg |
- (S)-3,5-DHPG
Selective group I mGlu receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204256 | 162870-29-3 | C8H9NO4 | 5 mg/10 mg |
- (S)-4C-PG
Competitve group I mGluR antagonist, with selectivity for mGlu1 over mGlu5 receptor.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203449 | 134052-73-6 | C9H9NO4 | 1 mg/5 mg/50 mg |
- (S)-4C3H-PG
Agonist for group II mGluRs. Competitive antagonist for group I mGluR1; mixed effects at mGluR5.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203249 | 85148-82-9 | C9H9NO5 | 1 mg/5 mg |
- (S)-CPW 399
Subtype-selective weakly desensitising AMPA agonist. At GluR1 and GluR2 subunit-containing AMPA receptors, exhibits potent agonist activity. Excitotoxic in vitro.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203690 | 389888-02-2 | C10H13N3O4 | 10 mg/50 mg |
- (S)-HexylHIBO
Group I mGlu antagonist. Enantiomer of hexylHIBO.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203691 | 334887-48-8 | C12H20N2O4 | 10 mg/50 mg |
- (S)-MCPG
An antagonist of the group I/II mGluRs. Active isomer of (RS)-MCPG preparations. Affects spatial learning and blocks induction of LTP through interaction with the mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202329 | 150145-89-4 | C10H11NO4 | 5 mg/25 mg |
- (S)-MPPG
This is the active isomer of (RS)-MPPG. It is a highly potent L-AP4-sensitive receptor antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222283 | 201608-25-5 | C9H12NO5P | 1 mg/5 mg |
- (S)-MPPG (cyclic)
This is a selective antagonist of group II mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222284 | n.n. | C10H12NO5P | 1 mg |
- Salsolinol-1-carboxylic acid
An amino acid that occurs naturally in the CNS.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204259 | 57256-34-5 | C11H13NO4 | 10 mg/50 mg |
- SDZ 220-040
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361354 | 174575-40-7 | C16H16Cl2NO6P | 10 mg/50 mg |
- SDZ 220-581
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361355 | n.n. | n.n. | 10 mg/50 mg |
- SIB 1757
A highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204277 | 31993-01-8 | C12H11N3O | 10 mg/50 mg |
- SIB 1893
Highly selective non-competitive antagonist for the metabotropic glutamate mGlu5 receptor subtype.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203262 | 6266-99-5 | C14H13N | 10 mg/50 mg |
- Spermidine trihydrochloride
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-360822 | 334-50-9 | C7H19N3•3HCl | 1 g/5 g |
- SYM 2206
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361369 | 173952-44-8 | C20H22N4O3 | 10 mg/50 mg |
- t-CAA
This is a potent in vivo inhibitor of glutamate uptake and a Kainate receptor agonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222334 | n.n. | C6H9NO4 | 1 mg |
- TCN 238
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-362803 | 125404-04-8 | C12H11N3 | 10 mg/50 mg |
- TCS 46b
Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204328 | 302799-86-6 | C22H23N3O | 10 mg/50 mg |
- Threo Ifenprodil hemitartrate
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361381 | 74991-34-7 | C21H27NO2.½C4H6O6 | 10 mg/50 mg |
- (±)-threo-3-Methylglutamic acid
A potent blocker of glutamate transport. Selective for EAAT2 and EAAT4 (IC50 values are 90, 109, 1600 and 1080 μM for EAAT2, EAAT4, EAAT1 and EAAT3 respectively).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204344 | 63088-04-0 | C6H11NO4 | 10 mg/50 mg |
- Topiramate
Anticonvulsant that antagonizes GluR5 kainate receptors (IC50 = 0.46 μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204350 | 97240-79-4 | C12H21NO8S | 10 mg/50 mg |
- trans-1,2-homo-ACPD
Selective antagonist for group II mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-208456 | n.n. | C8H13NO4 | 5 mg |
- trans-1,3-homo-ACPD
Equimolar mixture of (1R,3S)-homo-ACPD and (1S,3R)-homo-ACPD. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-205981 | n.n. | C8H13NO4 | 5 mg |
- TRANS-ACPD
An equimolar mixture of Trans-(1S,3R)-ACPD and Trans-(1R,3S)-APCD. Agonist of metabotropic glutamate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-202367 | 67684-64-4 | C7H11NO4 | 10 mg/50 mg |
- (±)-trans-Azetidine-2,4-dicarboxylic acid
Selective agonist for group I mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203300 | 161596-62-9 | C5H7NO4 | 1 mg |
- U-54494A hydrochloride
NMDA antagonist.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-200479 | 112465-94-8 | C18H24Cl2N2O··HCl | 5 mg/25 mg |
- UBP 282
AMPA and kainate receptor antagonist that distinguishes between motoneuron and dorsal root kainate receptors. Inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203715 | 544697-47-4 | C15H15N3O6 | 10 mg/50 mg |
- UBP 296
Potent and selective GluR5-subunit containing kainate receptor antagonist (apparent Kd = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres. Has little or no action at NMDA or group I mGlu receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204366 | n.n. | C15H15N3O6 | 10 mg/50 mg |
- UBP 301
Kainate potent receptor antagonist (apparent Kd = 5.94 mM). Displays ~ 30-fold selectivity over AMPA receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203716 | 569371-10-4 | C15H14IN3O6 | 10 mg/50 mg |
- UBP 302
Potent and selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist; active enantiomer of UBP 296.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204367 | n.n. | C15H15N3O6 | 10 mg/50 mg |
- UBP1112
A group III mGlu receptor antagonist that is selective (apparent Kd values are 5.1 and 488 μM for group III and group II mGlu receptors respectively; IC50 > 1 mM for group I, NMDA, AMPA and kainate receptors).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204368 | n.n. | C10H14NO5P | 10 mg/50 mg |
- VU 0155041
Potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). In vivo models of Parkinson's disease, active following i.c.v. administration.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204385 | n.n. | C14H15Cl2NO3 | 10 mg/50 mg |
- VU 0155041 sodium salt
A positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204386 | n.n. | C14H14Cl2NNaO3 | 10 mg/50 mg |
- VU 0361737
A selective positive allosteric modulator at mGlu4 receptors (EC50 values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors. Also a brain penetrant. | Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-301976 | 1161205-04-4 | C13H11CIN2O2 | 10 mg/50 mg |
- VU 1545
Positive allosteric modulator of metabotropic glutamate receptor 5 (mGlu5) (EC50 = 9.6 nM, Ki = 156 nM at rat mGlu5).| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204388 | 890764-63-3 | C22H15FN4O3 | 10 mg/50 mg |
- WAY 213613
Strong, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards metabotropic and ionotropic glutamate receptors.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-203720 | 868359-05-1 | C16H13BrF2N2O4 | 10 mg/50 mg |
- XE-CCG-I
Selective and highly active group II mGluR antagonist with a subtype specificity towards the mGlu3 receptor. XE-CCG-I has no activity towards group I and group III mGluRs.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-222421 | n.n. | C21H21NO5 | 1 mg |
- YM 230888
A selective mGLU1 antagonist reported to inhibit mGlu1-mediated inositol phosphate production.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-358843 | 446257-23-4 | C19H28N4OS | 10 mg/50 mg |
- YM 298198 hydrochloride
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361412 | 748758-45-4 | C18H22N4OS.HCl | 10 mg/50 mg |
- YM 90K hydrochloride
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361415 | 154164-30-4 | C11H7N5O4.HCl | 10 mg/50 mg |
- Z-Cyclopentyl-AP4
Group III mGlu receptor agonist that displays higher potency at mGlu4 than mGlu8 (EC50 values are 49 and 124 μM respectively) with no activity at mGlu7. Selectively inhibits synaptic activity in the lateral perforant pathway (IC50 values are 130 and 1859 μM in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4.
| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204413 | 103439-17-4 | C6H12NO5P | 10 mg/50 mg |
- ZJ 43
Has been shown to be a potent inhibitor of glutamate carboxypeptidase II and III. a potent inhibitor of glutamate carboxypeptidase II and III.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-361420 | 723331-20-2 | C12H20N2O7 | 1 mg/10 mg |
- ZK 200775
Competitive AMPA/kainate antagonist; inhibits currents induced by AMPA, kainate and NMDA; Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo.| Katalog # | CAS Nummer | Summenformel | Menge |
|---|
| sc-204421 | 161605-73-8 | C14H15N3O6F3P | 10 mg/50 mg |
|