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Cholinergics

  • 1-Acetyl-4-methylpiperazine hydrochloride
    Acetylcholine analog that acts as a nAChR agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20375960787-05-5C7H14N2O.HCl10 mg/50 mg
  • 1-Benzyl-1-methyl-4-cyclopentylmethoxycarbonyl-piperidinium bromide
    Strong inhibitor of the active transport of acetylcholine by synaptic vesicles.
    Katalog #CAS NummerSummenformelMenge
    sc-220461n.n.C20H30BrNO25 mg
  • 4-Acetyl-1,1-dimethylpiperazinium iodide
    Structural analog of acetylcholine that acts as a nicotinic agonist (Ki = 29.9 nM at α4β2). Upregulates the number of α4β2 binding sites in M10 cells in vitro by 440%.
    Katalog #CAS NummerSummenformelMenge
    sc-20347375667-84-4C8N17IN2O10 mg/50 mg
  • 4-DAMP
    4-DAMP is a muscarinic receptor antagonist. Shown to be a useful ligand for labeling the M1 and M3 muscarinic receptor subtypes.
    Katalog #CAS NummerSummenformelMenge
    sc-2001671952-15-4C21H26INO250 mg
  • 5-IODO-A-85380 dihydrochloride hydrate
    A highly potent and subtype-selective agonist for the α4β2 and α6β2 nicotinic acetylcholine receptors; activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release.
    Katalog #CAS NummerSummenformelMenge
    sc-203478213764-92-2C9H11IN2O ·2HCl5 mg
  • 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative
    Precursor to the highly potent and selective ligand for the α4β2 nicotinic receptor, 5-Iodo-A-85380. Suitable for radioiodination.
    Katalog #CAS NummerSummenformelMenge
    sc-203479213766-21-3C17H28N2O3Sn200 µg
  • 5-Methylfurmethide
    Potent muscarinic agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-2028911197-60-0C9H16INO10 mg/50 mg
  • 14-Acetylvirescenine from Delphinium sp.
    Blocks the propagation of the action potential at the nicotinic cholinoreceptors of vegetative ganglia and neuro-muscular junctions. Has hypotensive and curare-like action.
    Katalog #CAS NummerSummenformelMenge
    sc-29797371609-79-5C25H39NO710 mg
  • A-85380 dihydrochloride
    A potent and selective neuronal nicotinic acetylcholine receptor (nAChR) agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-300146n.n.C9H14Cl2N2O5 mg
  • α-NETA
    Potent, fluorescent inhibitor of choline acetyltransferase.
    Katalog #CAS NummerSummenformelMenge
    sc-22119031059-54-8C16H20INO5 mg/25 mg
  • AB-MECA
    This is a high affinity A3 adenosine receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-239176152918-26-8C18H21N7O41 mg
  • Acephate
    Anticholinesterase insecticide that produces cholinotoxicity. Displays weak inhibition of rat acetylcholinesterase (AChE) but potently inhibits cockroach AChE
    Katalog #CAS NummerSummenformelMenge
    sc-20380030560-19-1C4H10NO3PS50 mg
  • Acetyl-L-carnitine chloride
    Katalog #CAS NummerSummenformelMenge
    sc-2107475080-50-2C9H18NClO41 g
  • (±)-Acetylcarnitine chloride
    A weak cholinergic agonist. Acylcarnitines are important intermediates in lipid metabolism.
    Katalog #CAS NummerSummenformelMenge
    sc-2034952504-11-2C9H18CINO4100 mg
  • Acetylcholine chloride
    A cholinergic neurotransmitter that can induce the opening of calcium channels, as well as act on nicotinic and muscarinic acetylcholine receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20290460-31-1C7H16ClNO25 g/25 g
  • Acetylcholine-d9 Chloride
    Cholinergic.
    Katalog #CAS NummerSummenformelMenge
    sc-217569344298-95-9C7H16ClNO25 mg
  • Acetylethylcholine mustard hydrochloride
    An inhibitor of choline acetyl-transferase. A precursor for ethylcholine mustard aziridinium ion (AF-64A). An irreversible ligand for the high affinity choline transport system. And a specific presynaptic long action cholinotoxin.
    Katalog #CAS NummerSummenformelMenge
    sc-281685103994-00-9C8H16CINO2•HCI5 mg/25 mg
  • Acetylthiocholine iodide
    This compound is an acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-2083231866-15-5C7H16INOS1 g/5 g
  • AF-DX 116
    SelectiveM2 antagonist
    Katalog #CAS NummerSummenformelMenge
    sc-223772102394-31-0C24H31N5O210 mg
  • AF-DX 384
    Potent M2/M4 selective antagonist (pKi values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human M2, M4, M1, M3 and M5 receptors respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-203498118290-27-0C28H42N6O5S10 mg/50 mg
  • Ambenonium dichloride
    A selective rapidly reversible noncovalent inhibitor of AChE. Demonstrates high affinity at AChE (IC50 = 0.698 nM) and lower affinity at BChE (IC50 = 8.20 μM).
    Katalog #CAS NummerSummenformelMenge
    sc-20350752022-31-8C28H42Cl4N4O2•xH2O10 mg/50 mg
  • Aminobenztropine
    Muscarinic ligand displaying high affinity. Useful in affinity purification of muscarinic cholinergic receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-30019488097-86-3C21H26N2O50 mg
  • (±)-Anatoxin A
    A cyanotoxin agonist of nicotinic acetylcholine receptors. Produces neurotoxicity through overstimulation of cholinergic neurons.
    Katalog #CAS NummerSummenformelMenge
    sc-20018564285-06-9C10H15NO··C4H4O41 mg
  • AQ-RA 741
    High affinity, selective muscarinic M2 receptor antagonist (pKi values are 8.3, 7.7 and 6.82 for M2 , M1 and M3 receptors, respectively). In vivo, displays cardioselectivity over tracheal, intestinal and bladder muscarinic receptors; inhibits vagally and agonist-induced bradycardia.
    Katalog #CAS NummerSummenformelMenge
    sc-203517123548-16-3C27H37N5O210 mg/50 mg
  • Arecaidine but-2-ynyl ester tosylate
    A potent muscarinicagonist, 4.6-fold that is selective for M2 receptors in the atrium versus those in the ileum.
    Katalog #CAS NummerSummenformelMenge
    sc-203519499-04-7C11H15NO2•C7H8SO310 mg/50 mg
  • Arecaidine propargyl ester tosylate
    A potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203520147202-94-6C10H13NO2S ·C7H8SO310 mg/50 mg
  • Atropine Sulfate Monohydrate
    A cholinergic receptor antagonist isolated from Atropa belladona L., Datura stramonium L., and other plants of Solanaceae family.
    Katalog #CAS NummerSummenformelMenge
    sc-2033225908-99-6(C17H23NO3)2 ·H2SO4•H2O100 mg
  • Benzoquinonium Dibromide
    Nicotinic antagonist, ganglion blocker. Activates single channels but blocks open channels at nicotinic receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203839311-09-1C34H50Br2N4O210 mg/50 mg
  • Benzoylcholine chloride
    Katalog #CAS NummerSummenformelMenge
    sc-2145902964-09-2C12H18ClNO210 g/50 g
  • Bevonium Methyl Sulfate
    An antibacterial used as an anticholinergic, antispasmodic, and brochodilator.
    Katalog #CAS NummerSummenformelMenge
    sc-2109145205-82-3C23H31NO7S5 mg
  • Biperiden hydrochloride
    Muscarinic receptor antagonist that displays some selectivity for the M1 subtype (Ki values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M1, M4, M3, M2 and M5 receptors respectively). Displays antiparkinsonian activity. Alleviates extrapyramidal symptoms associated with antipsychotic drugs.
    Katalog #CAS NummerSummenformelMenge
    sc-2038461235-82-1C21H29NO.HCl10 mg/50 mg
  • BQCA
    Highly selective allosteric potentiator of the M1 muscarinic acetylcholine receptor (mAChR). Reduces the concentration of ACh required to activate M1 up to 129-fold and displays no potentiation, agonism or antagonism activity at other mAChRs at concentrations up to 100µM. Reverses scopolamine-induced memory deficits and increases blood flow to the cerebral cortex in mouse models. M1 activators slow the progression of Alzheimers disease. Induces β-arrestin recruitment to M1. At 100µM, it activated M1 in the absence of ACh to ca. 50% maximal response. At 10µM, it reduced the concentration of ACh required to displace radioligand by 45-fold. In vivo experiments were carried out in mice at 15 or 20mg/kg. The compound is cell permeable, brain penetrant and orally active.
    Katalog #CAS NummerSummenformelMenge
    sc-280627n.n.C18H15NO410 mg/50 mg
  • Bretylium Tosylate
    Katalog #CAS NummerSummenformelMenge
    sc-36074561-75-6C18H24BrNO3S200 mg
  • Carbachol
    Shown to be an anti-apoptosis agent also reported to prevent an increase in endothelial cell permeability induced by TNF-α and a decrease in phosphor-ERK1/2.
    Katalog #CAS NummerSummenformelMenge
    sc-20209251-83-2C6H15ClN2O2100 mg
  • (Carbethoxymethylene)triphenylphosphorane
    A phosphorane compound for Wittig olefinations.
    Katalog #CAS NummerSummenformelMenge
    sc-2074031099-45-2C22H21O2P50 g
  • Chk2 Inhibitor
    A potent and selective inhibitor of Chk2 that contains anti-proliferative and anti-inflammatory properties. It has also been shown to target ATP binding pockets of Chk2.
    Katalog #CAS NummerSummenformelMenge
    sc-203885724708-21-8C15H13N5O2500 µg
  • Chlorisondamine diiodide
    A long lasting nicotinic antagonist (IC50 ~ 1.6 mM). Blockade of central nicotinic responses induced by chlorisondamine can persist for several weeks.
    Katalog #CAS NummerSummenformelMenge
    sc-20354796750-66-2C14H20Cl4N2 ·2I10 mg/50 mg
  • Clidinium Bromide
    Clidinium Bromide is used as an antiplasmodic and is an anticholinergic.
    Katalog #CAS NummerSummenformelMenge
    sc-2074493485-62-9C22H26BrNO31 g
  • Cytisine
    Pyridine-like alkaloid. Nicotine agonist. Ligand for many nAChR subtypes. Potent agonist of α3β4 and α7 nicotinic ACh receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-203015485-35-8C11H14N2O5 mg/25 mg
  • D,L-Trihexyphenidyl, Hydrochloride
    Artane is an anticholinergic tertiary amine that can gain access to the CNS. It is used to treat parkinsonism and the extrapyramidal side effects of anti-psychotic drugs.
    Katalog #CAS NummerSummenformelMenge
    sc-21120158947-95-8C20H31NO ·HCl5 g
  • Darifenacin Hydrobromide
    A medication used to treat urinary incontenance where the mechanism of action is blocking the M3 musarinnic acetylcholine receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-204708133099-07-7C28H30N2O2 ·HBr10 mg/25 mg
  • DAU 5884 hydrochloride
    Highly potent and selective M3 muscarinic receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-203912131780-47-7C17H21N3O3•HCl•xH2O10 mg/50 mg
  • (±)-Decanoylcarnitine chloride
    Homolog of acetylcarnitine chloride (sc-203495). Intermediate in lipid metabolism.
    Katalog #CAS NummerSummenformelMenge
    sc-20391414919-36-9C17H34ClNO450 mg
  • Desformylflustrabromine hydrochloride
    A positive allosteric modulator of α4β2 nicotinic acetylcholine receptors (nAChRs) with selectivity over α7; moderate cytotoxicity noted in HCT-116 cell cultures.
    Katalog #CAS NummerSummenformelMenge
    sc-358800474657-72-2C16H21BrN2•HCl10 mg/50 mg
  • Desoxypeganine hydrochloride
    Acetylcholinesterase inhibitor that has been used in the treatment of Alzheimer's dementia.
    Katalog #CAS NummerSummenformelMenge
    sc-20471261939-05-7C11H12N225 mg/100 mg
  • Dexetimide·HCl (R 16470)
    Dexetimide, also known as R 16470 is a piperidine anticholinergic and a high affinity muscarinic receptor antagonist used to treat neuroleptic-induced parkinsonism.
    Katalog #CAS NummerSummenformelMenge
    sc-2001665633-14-7C23H26N2O2•HCl10 mg
  • Dihydro-β-erythroidine hydrobromide
    An acetylcholine receptor antagonist which has been shown to act in a competitive manner. Possesses selectivity for the neuronal α4 subunit, and has been shown to antagonize the effects of nicotine in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-20392029734-68-7C16H21NO3 ·HBr10 mg/50 mg
  • DMAB-anabaseine dihydrochloride
    α7-containing neuronal nicotinic receptor partial agonist and antagonist at α4β2 and other nicotinic receptors. Exhibits specific cognition-enhancing effects; improves rat long-term memory.
    Katalog #CAS NummerSummenformelMenge
    sc-20356832013-69-7C19H21N3 ·2HCl10 mg
  • Edrophonium chloride
    An acetycholinesterase inhibitor.
    Katalog #CAS NummerSummenformelMenge
    sc-207610116-38-1C10H16ClNO250 mg/1 g
  • (±)-Epibatidine
    Epibatidine is an analgesic alkaloid isolated from the skin of the poison frog Epipedobates tricolor. It is the most potent nicotinic acetylcholine receptor agonist known.
    Katalog #CAS NummerSummenformelMenge
    sc-200177140111-52-0C11H13ClN21 mg/5 mg
  • (+/-)-Epibatidine dihydrochloride hydrate
    Katalog #CAS NummerSummenformelMenge
    sc-300512162885-01-0 (anhydrous)C11H13ClN2•2HCl•xH2O5 mg
  • Galanthamine
    A selective acetylcholinesterase inhibitor that is useful for the treatment of Alzheimerís disease.
    Katalog #CAS NummerSummenformelMenge
    sc-218556357-70-0C17H21NO310 mg
  • Galanthamine Hydrobromide
    A competitive and reversible acetylcholinesterase inhibitor, which displays allosteric potentiating effects at nicotinic receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-2001791953-04-4C17H21NO3··HBr25 mg/100 mg
  • Gallamine Triethiodide
    M2 muscarinic antagonist with pronounced cardioselectivity. It acts by combining with the cholinergic receptor sites in muscle and competitively blocks the transmitter action of acetylcholine.
    Katalog #CAS NummerSummenformelMenge
    sc-20017565-29-2C30H60I3N3O31 g/5 g
  • Himbacine
    Himbacine is an alkaloid muscarinic receptor antagonist displaying more potent activity associated with M2 and M4 subtypes.
    Katalog #CAS NummerSummenformelMenge
    sc-2001816879-74-9C22H35NO21 mg/5 mg
  • Hydroxytacrine maleate
    A cholinesterase inhibitor and a potential Alzheimer’s therapeutic of low toxicity.
    Katalog #CAS NummerSummenformelMenge
    sc-200168118909-22-1C13H14N2O··C4H4O4200 mg/1 g
  • Ipratropium bromide
    Muscarinic antagonist, bronchodilator. N-Isopropyl salt of atropine.
    Katalog #CAS NummerSummenformelMenge
    sc-20360622254-24-6C20H30BrNO3100 mg
  • Itopride Hydrochloride
    A gastroprokinetic benzamide derviative that inhibits acetylcholinesterase reversibly.
    Katalog #CAS NummerSummenformelMenge
    sc-204778122892-31-3C20H26N2O4 ·HCl1 g/5 g
  • J 104129
    Potent M3 muscarinic receptor antagonist that displays ~ 120-fold selectivity over M2 receptors (Ki values are 4.2, 19 and 490 nM for human M3, M1 and M2 receptors respectively). Exhibits > 250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (KB values are 3.3 and 170 nM for rat trachea M3 and rat right atria M2 receptors respectively).
    Katalog #CAS NummerSummenformelMenge
    sc-203610244277-89-2C24H36N2O2 ·C4H4O410 mg
  • LY 2365109 hydrochloride
    Potent and selective glycine transporter 1 (GlyT1) inhibitor (IC50 values are 15.8 and > 30 000 nM at GlyT1 and GlyT2 respectively). Induces a dose-dependent elevation in CSF levels of glycine, and enhances acetylcholine and dopamine release in the striatum and prefrontal cortex respectively. Profound locomotor and respiratory impairments at higher doses.
    Katalog #CAS NummerSummenformelMenge
    sc-204063868265-28-5C22H28ClNO510 mg/50 mg
  • L-Hyoscyamine
    Katalog #CAS NummerSummenformelMenge
    sc-295290101-31-5C17H23NO31 g/5 g
  • Lobeline hydrochloride
    A potent agonist of the nAChRs. Modulates 86Rb+ efflux. Inhibits dopamine uptake into synaptic vesicles.
    Katalog #CAS NummerSummenformelMenge
    sc-203114134-63-4C22H27NO2 ·HCl50 mg/1 g
  • LY2033298
    LY2033298 is an allosteric potentiator that is highly selective for the human M4 mAChR subtype.
    Katalog #CAS NummerSummenformelMenge
    sc-300942886047-13-8C13H14ClN3O2S5 mg
  • Mecamylamine Hydrochloride
    A noncompetitive and nonselective antagonist of nicotinic acetylcholine receptors, that preferentially blocks nicotinic receptors at autonomic ganglia and is able to cross the blood brain barrier.
    Katalog #CAS NummerSummenformelMenge
    sc-205742826-39-1C11H21N ·HCl5 mg/25 mg
  • Mepenzolate Bromide
    Anticholinergic.
    Katalog #CAS NummerSummenformelMenge
    sc-35827276-90-4C21H26BrNO35 g
  • Methyllycaconitine citrate
    Potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM. Attenuates METH-induced neurotoxicity in mouse striatum in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-20363221019-30-7C37H50N2O10 ·C6H8O75 mg/25 mg
  • Methyllycaconitine Perchlorate, Delphinium sp.
    Has high affinity (nM range) for a subtype of the neuronal acetylcholine receptor (nAchR) in the brain; exhibits micromolar affinity for muscle acetylcholine receptor and for α-bungarotoxin-insensitive neuronal nAChR.
    Katalog #CAS NummerSummenformelMenge
    sc-221938n.n.C37H51ClN2O145 mg
  • MG 624
    a7neuronal nicotinic receptor antagonist. Inhibits a-Bgtx binding to chick a7 and a4b2 subtypes.
    Katalog #CAS NummerSummenformelMenge
    sc-20408277257-42-2C22H30NOI10 mg/50 mg
  • Milameline hydrochloride
    Muscarinic receptor agonist that displays roughly equal affinity at all receptor subtypes (Ki values are 2.3, 2.4, 3.6, 3.8 and 4.3 μM for hM1, hM2, hM3, hM4 and hM5 receptors respectively). Cognitive enhancer; reverses spatial memory deficits in rats.
    Katalog #CAS NummerSummenformelMenge
    sc-204085139886-32-1C8H14N2O•HCl10 mg/50 mg
  • MR 16728 hydrochloride
    A cetiedil analog that stimulates the release of acetylcholine from synaptosomes.
    Katalog #CAS NummerSummenformelMenge
    sc-204099147614-21-9C23H36N2O ·HCl10 mg/50 mg
  • (±)-Myristoylcarnitine chloride
    Homolog of acetylcarnitine chloride. Intermediate in lipid metabolism.
    Katalog #CAS NummerSummenformelMenge
    sc-20410814919-38-1C21H42ClNO450 mg
  • N,N,N-Trimethyl-1-(4-trans-stilbenoxy)-2-propylammonium iodide
    It is an antagonist of nicotinic acetylcholine receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-301439n.n.C20H26INO25 mg
  • NDNI hydriodide
    This product is a highly selective α4β2 nicotinic receptor antagonist
    Katalog #CAS NummerSummenformelMenge
    sc-301459244025-06-7C20H36I2N25 mg
  • Neostigmine Bromide
    An acetylcholine esterase inhibitor that has protective effects against gastric carcinogenesis. May provide analgesic effects in neoplasia patients.
    Katalog #CAS NummerSummenformelMenge
    sc-204816114-80-7C12H19BrN2O2250 mg/1 g
  • (-)-Nicotine ditartrate
    Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.
    Katalog #CAS NummerSummenformelMenge
    sc-20316165-31-6C10H14N2 ·2C4H6O6100 mg
  • Nitrocaramiphen hydrochloride
    M1 selective muscarinic antagonist. 71-fold selectivity over M2.
    Katalog #CAS NummerSummenformelMenge
    sc-204129n.n.C18H26N2O4.HCl10 mg/50 mg
  • NS 1738
    Selective a7 nAchR allosteric modulator. a4b2, a3b3 and a1-containing receptors display no substantial activity. In vivo, displays cognitive-enhancing properties.
    Katalog #CAS NummerSummenformelMenge
    sc-204136501684-93-1C14H9Cl2F3N2O210 mg/50 mg
  • Obidoxime Chloride
    Cholinesterase reactivator.
    Katalog #CAS NummerSummenformelMenge
    sc-212467114-90-9C14H16Cl2N4O31 g
  • (±)-Octanoylcarnitine chloride
    Homolog of acetylcarnitine chloride (sc-203495). Acylcarnitines are important intermediates in lipid metabolism.
    Katalog #CAS NummerSummenformelMenge
    sc-20414318822-86-1C15H30ClNO450 mg
  • Oxotremorine M
    A muscarinic receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20365663939-65-1C11H19IN2O100 mg
  • Oxotremorine Sesquifumarate
    An M2 and M4 Muscarinic acetylcholine receptor agonist. Combinations of oxotremorine and other muscarinic agonists display supra-additive memory enhancement.
    Katalog #CAS NummerSummenformelMenge
    sc-20017017360-35-9C12H18N2O•1.5C4H4O4100 mg/500 mg
  • Pancuronium dibromide
    Nicotine (neuromuscular) antagonist. Skeletal muscle relaxant.
    Katalog #CAS NummerSummenformelMenge
    sc-20317915500-66-0C35H60Br2N2O410 mg/50 mg
  • PD 102807
    Selective M4 muscarinic receptor antagonist. IC50 values are 91, 6559, 3441, 950 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively.
    Katalog #CAS NummerSummenformelMenge
    sc-20365923062-91-1C23H24N2O410 mg/50 mg
  • PG-9 maleate
    A potent analgesic and nootropic agent. Increases release of acetylcholine.
    Katalog #CAS NummerSummenformelMenge
    sc-204184n.n.C17H22BrNO2 ·C4H4O410 mg/50 mg
  • PHA 568487
    Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3β4 and α1β1δγ respectively, and % inhibition is < 1 and 5 % for α4β2 and hERG respectively). Orally active and brain penetrant.
    Katalog #CAS NummerSummenformelMenge
    sc-204186527680-56-4C16H20N2O3 ·C4H4O410 mg/50 mg
  • Phenserine
    Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of Aβ and amyloid precursor protein (APP). Improves morris water maze performance of scopolamine-treated rats.
    Katalog #CAS NummerSummenformelMenge
    sc-204188101246-66-6C20H23N3O250 mg
  • Physostigmine hemisulfate
    An analogue of Physostigmine.
    Katalog #CAS NummerSummenformelMenge
    sc-20366164-47-1(C15H21N3O2)2•H2SO4100 mg
  • (+)-Pilocarpine hydrochloride
    Cholinergic agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-20319654-71-7C11H16N2O2.HCl1 g
  • Pilocarpine nitrate salt
    A nonselective muscarinic acetylcholine receptor agonist, that is used to produce an experimental model of epilepsy.
    Katalog #CAS NummerSummenformelMenge
    sc-250722148-72-1C11H16N2O2•HNO310 g
  • Pirenzepine Dihydrochloride
    A selective antagonist for the M1 muscarinic receptor (mAChR) with reported IC50 = 2.51x10-7.
    Katalog #CAS NummerSummenformelMenge
    sc-20419729868-97-1C19H21N5O2 ·2HCl100 mg
  • PNU 120596
    A type II positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor (nAChR) located on the somatodendritic membrane of hippocampal interneurons.
    Katalog #CAS NummerSummenformelMenge
    sc-203200501925-31-1C13H14ClN3O41 mg/5 mg
  • PNU-282,987
    PNU-282,987 is a highly selective agonist for the homomeric α7 nicotinic acetylcholine receptor (α7 nAChR).
    Katalog #CAS NummerSummenformelMenge
    sc-200187123464-89-1C14H17ClN2O10 mg/50 mg
  • PNU-282987 hydrate
    PNU-282,987 is a highly selective agonist for the homomeric α7 nicotinic acetylcholine receptor (α7 nAChR).
    Katalog #CAS NummerSummenformelMenge
    sc-301554123464-89-1 (anhydrous)C14H17ClN2O•HCl•xH2O10 mg
  • Procyclidine hydrochloride
    An atropine-like antispasmodic.
    Katalog #CAS NummerSummenformelMenge
    sc-2507771508-76-5C19H29NO ·HCl1 g
  • (±)-Propionylcarnitine chloride
    Homolog of acetylcarnitine chloride (sc-203495). Acylcarnitines are important intermediates in lipid metabolism.
    Katalog #CAS NummerSummenformelMenge
    sc-20486417298-37-2C10H20CINO450 mg
  • Propiverine, Hydrochloride
    Used for treatment of urinary incontinence.
    Katalog #CAS NummerSummenformelMenge
    sc-21259454556-98-8C23H30ClNO3100 mg
  • R(-)-Quinuclidinyl benzilate methiodide
    Nonselective muscarinic acetylcholine receptor antagonist.
    Katalog #CAS NummerSummenformelMenge
    sc-301655n.n.C22H26INO32 mg
  • Rivastigmine Hydrogen Tartrate
    A parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and Parkinson's disease.
    Katalog #CAS NummerSummenformelMenge
    sc-204883129101-54-8C18H28N2O8100 mg/250 mg
  • RJR 2403 oxalate
    CNS selective nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Active in vivo.
    Katalog #CAS NummerSummenformelMenge
    sc-204884183288-99-5C10H14N2 ·C4H4O410 mg/50 mg
  • RJR 2429 dihydrochloride
    Potent nAChR agonist that displays selectivity for α4β2 (Ki = 1 nM) and α1βγδ subtypes (EC50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC50 = 2 nM) and inhibits ion flux in thalamic neurons (IC50 = 154 nM). Also putative α3β4 agonist that potentiates catecholamine release.
    Katalog #CAS NummerSummenformelMenge
    sc-20423791556-75-1C12H16N2 ·2HCl10 mg/50 mg
  • S-Butyrylthiocholine Iodide
    Chromogenic substrate for cholinesterases. Cleavage is measured colorimetrically at 405 nm.
    Katalog #CAS NummerSummenformelMenge
    sc-2867401866-16-6C9H20INOS5 g
  • (S)-(+)-Dimethindene maleate
    Katalog #CAS NummerSummenformelMenge
    sc-361329121367-05-3C20H24N2.C4H4O410 mg/50 mg
  • (-)-Scopolamine hydrobromide
    A competitive antagonist of acetylcholine muscarinic receptors, with selectivity for the M1 subtype.
    Katalog #CAS NummerSummenformelMenge
    sc-203259114-49-8C17H21NO4 ·HBr1 g
  • SM-21 maleate
    Potent and selective σ2 antagonist with central effects following systemic administration. Increases release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent.
    Katalog #CAS NummerSummenformelMenge
    sc-204289155058-71-2C18H24ClNO3•C4H4O410 mg/50 mg
  • Solifenacin Hydrochloride
    A muscarinic M3 receptor antagonist that is used in treatment of urinary incontinence.
    Katalog #CAS NummerSummenformelMenge
    sc-212950180468-39-7C23H27ClN2O210 mg
  • Succinylcholine chloride dihydrate
    Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane. A neuromuscular blocking agent.
    Katalog #CAS NummerSummenformelMenge
    sc-2129656101-15-1C14H30Cl2N2O4•2H2O25 g
  • Tacrine·HCl
    Shown to be an anticholinesterase that reversibly inhibits acetylcholine esterase. Also has been reported to display hepatotoxicity via inhibition of DNA synthesis in hepatocytes.
    Katalog #CAS NummerSummenformelMenge
    sc-2001721684-40-8C13H14N2 ·HCl1 g/5 g
  • TC 1698 dihydrochloride
    Selective nicotinic α7 receptor agonist (EC50 = 440 nM). Displays a weak partial agonist/antagonist activity at β-subunit-containing receptors. Also neuroprotective.
    Katalog #CAS NummerSummenformelMenge
    sc-204324700834-58-8C13H18N2.2HCl10 mg/50 mg
  • TC 2559 difumarate
    Subtype-selective partial agonist for α4β2 nicotinic acetylcholine receptors (EC50 values are 0.18, 12.5, 14.0, > 30, > 100 and > 100 μM for α4β2, α4β4, α2β4, α3β4, α3β2 and α7 receptor subtypes respectively). Displays selectivity for (α4)2(β2)3 receptor stoichiometry and enhanced CNS-PNS selectivity ratio. Attenuates scopolamine-induced cognitive deficits in a step-through passive avoidance task.
    Katalog #CAS NummerSummenformelMenge
    sc-203707212332-35-9C12H18N2O ·2C4H4O410 mg/50 mg
  • Telenzepine dihydrochloride
    A salt of Telenzepine that is a potent and selective muscarnic receptor antagonist for M1 and M2 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-204332147416-96-4C19H24Cl2N4O2S10 mg/50 mg
  • Telenzepine dihydrochloride hydrate
    A derivative of Telenzepine that is a potent and selective muscarnic receptor antagonist for M1 and M2 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-251109147416-96-4 (anhydrous)C19H22N4O2S•2HCl•xH2O10 mg/25 mg
  • Tropanyl 2-(4-chlorophenoxy)propionate maleate
    Strong analgesic and nootropic agent. Responsible for the increased release of acetylcholine at central muscarinic synapses.
    Katalog #CAS NummerSummenformelMenge
    sc-222373n.n.C17H22ClNO3•C4H4O410 mg
  • Tropanyl 2-(4-chlorophenylthio)butanoate oxalate
    Potent analgesic and nootropic agent. Increases release of acetylcholine at central muscarinic synapses.
    Katalog #CAS NummerSummenformelMenge
    sc-205983n.n.C20H26ClNO6S10 mg
  • Tropanyl 2-naphthoxypropionate maleate
    Strong analgesic and nootropic agent. Responsible for the increased release of acetylcholine at central muscarinic synapses.
    Katalog #CAS NummerSummenformelMenge
    sc-222374n.n.C25H29NO710 mg
  • (+)-Tubocurarine chloride pentahydrate
    An inhibitor of the acetylcholine receptor.
    Katalog #CAS NummerSummenformelMenge
    sc-2160296989-98-6C37H42Cl2N2O6 ·5H2O250 mg/1 g
  • (±)-Vesamicol·HCl (AH-5183)
    An inhibitor of acetylcholine transport into vesicles. Reduces the storage and subsequent release of acetylcholine into neurons.
    Katalog #CAS NummerSummenformelMenge
    sc-200174120447-62-3C17H25NO•HCl200 mg
  • VU 0238429
    A selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5, M1 and M3 receptors respectively). Displays no activity at M2 and M4 receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-3019751160247-92-6C17H12F3NO410 mg/50 mg
  • VU 10010
    Selective allosteric potentiator of M4 acetylcholine receptors (EC50 values are 33 and 0.7 nM for ACh in the absence and presence of VU10010 respectively). Binds to an allosteric site on the receptor increasing affinity coupling to G-proteins and for ACh.
    Katalog #CAS NummerSummenformelMenge
    sc-204387633283-39-3C17H16ClN3OS10 mg/50 mg
  • VU 152100
    A selective positive allosteric modulator of M4 muscarinic acetylcholine receptors (mAChRs).
    Katalog #CAS NummerSummenformelMenge
    sc-311554n.n.C18H19N3O2S10 mg/50 mg
  • W84 dibromide
    One of the first potent allosteric modulators of muscarinic receptors, selective for M2-receptors.
    Katalog #CAS NummerSummenformelMenge
    sc-20331221093-51-6C32H44Br2N4O45 mg
  • Xanomeline L-tartrate hydrate
    Xanomeline L-tartate is a M1 muscarinic receptor agonist.
    Katalog #CAS NummerSummenformelMenge
    sc-301981131986-45-3C14H23N3OS•xC4H6O6•yH2O5 mg
  • Xanomeline oxalate
    Functionally selective muscarinic M1 receptor agonist which exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.
    Katalog #CAS NummerSummenformelMenge
    sc-204402141064-23-5C14H23N3OS ·C2H2O410 mg/50 mg
  • Zamifenacin fumarate
    Selective M3 muscarinic antagonist receptor (pKi values are 8.52, 7.93, 7.90 and 7.78 for M3, M2, M1 and M4 receptors respectively). Displays higher affinity at ileal M3 receptors (pKi = 9.3) compared to oesophageal and tracheal M3 receptors (pKi values are 8.8 and 8.2 respectively). In vivo, inhibits gastrointestinal motility in the absence of cardiovascular effects.
    Katalog #CAS NummerSummenformelMenge
    sc-204416127308-98-9C31H33NO710 mg/50 mg