Calpain Inhibitors

• ALLM (Calpain Inhibitor)
  Cell-permeable, peptide aldehyde inhibitor of calpain and other neutral cysteine proteases. Potent inhibitor of cathepsin L and cathepsin B

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201268	136632-32-1	C19H35N5O4S	5 mg/25 mg

• ALLN

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-221236	110044-82-1	C20H37N3O4	5 mg

• Calpain Inhibitor VI
  A cell permeable peptide aldehyde which functions as a reversible calpain inhibitor. Calpain Inhibitor VI strongly inhibits cathepsin B and cathepsin L.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-293979	190274-53-4	C17H25FN2O4S	1 mg/5 mg

• Calpain Inhibitor XII
  A cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1. Has been shown to inhibit calpain-2 and human cathepsin B only at higher concentrations.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300318	n.n.	C26H34N4O5	1 mg/5 mg

• Calpeptin
  A cell permeable calpain inhibitor. Research shows that Calpeptin is the most effective inhibitor of m-calpain out of calpain inhibitors 1 and 2, and can fully block cleavage of PLC-β 3 enzymes.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202516	117591-20-5	C20H30N2O4	10 mg/50 mg

• E-64-c
  An effective synthetic calpain inhibitor composed from E-64 (sc-201276). Forms a complex with papain by binding via a thioether covalent bond, and inhibits cathepsins B and L.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201278	76684-89-4	C15H26N2O5	1 mg/5 mg

• E-64-d
  Derivative of the membrane permeant E-64c (sc-201278), acts as a potent inhibitor of thiol protease, and can block calpain activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201280	88321-09-9	C17H30N2O5	1 mg/5 mg

• γ-Secretase Inhibitor II
  A cell-permeable, reversible inhibitor of ©-secretase that reduces the formation of both Aβ total and Aβ1-42 using CHO cultures stably transfected with Amyloid Precursor Protein-751.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-302013	n.n.	C20H30N2O4	1 mg/5 mg

• MDL-28170
  A Calpain 1 inhibitor that inhibits oxidative damage-induced apoptosis in neuronal and immune cells. Also shown to prevent anoxia in murine optic nerves.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201301	88191-84-8	C22H26N2O4	10 mg/50 mg

• PD 150606
  A cell-permeable, non-competitive, selective, non-peptide calpain inhibitor for calpain-1 and for calpain-2 directed towards the Ca+ binding sites of calpain.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-222133	659-22-3	C9H7IO2S	5 mg/25 mg

• PD 151746
  A cell-permeable, non-peptidic, and highly selective calpain inhibitor directed towards the Ca+ binding sites of calpain. Exhibits greater selectivity over calpain-1 than calpain-2. Shown to prevent cycloheximide-induced apoptosis.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-222134	n.n.	C11H8FNO2	5 mg

• PGP-4008
  This is a selective P-glycoprotein (Pgp) inhibitor. It effectively reverses Pgp mediated drug resistance in NCI/ADR cells, but has no effect on the drug sensitivities of MCF-7/VP cells that overexpress MRP1.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-222152	n.n.	C26H23N3O	2 mg/10 mg