Calmodulin Inhibitors

• A-7 hydrochloride
  A potent calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC₅₀ of 3 μM).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203794	79127-24-5	C20H29ClN2O2S ·HCl	10 mg

• Calmidazolium Chloride
  An antagonist of calmodulin and blocker of calmodulin-mediated protein activations. Stimulates Ca²⁺ entry by a mechanism distinct from store-operated Ca²⁺ entry in HeLa cells. Demonstrates uncompetitive inhibition of platelet and sarcoplasmic reticulum Ca²⁺-ATPase activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201494	57265-65-3	C31H23Cl6N2O··Cl	10 mg/50 mg

• CGS 9343B
  Calmodulin antagonist that inhibits calmodulin-stimulated cAMP phosphodiesterase activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203883	109826-27-9	C26H28N4O2 ·C4H4O4	10 mg

• E6 Berbamine
  A potent, selective, cell-permeable calmodulin antagonist which inhibits calmodulin-dependent enzymes such as MLC kinase (IC₅₀=8 µM) and phosphodiesterase I (IC₅₀=0.53 µM).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-221573	73885-53-7	C44H43N3O9	10 mg/50 mg

• Fluphenazine-N-2-chloroethane･2HCl
  Irreversibly inhibits calmodulin-induced activation of CNPase. Irreversible antagonist of D2 and D1 dopamine receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201502	83016-35-7	C22H25ClF3N3S ·2HCl	50 mg

• J-8 hydrochloride
  Highly selective calmodulin (CaM) antagonist. Inhibits Ca²⁺/calmodulin-dependent phosphodiesterase. Selectivity over Ca²⁺+/CaM-dependent enzymes compared with Ca²⁺-dependent but CaM-independent enzymes, e.g. protein kinase C (PKC) and transglutaminase.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-221772	187937-24-2	C18H25IN2O2S•HCl	5 mg/25 mg

• Trifluoperazine·2HCl (Stelazine)
  A phenothiazine compound with antiadrenergic and antidopaminergic effects.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201498	440-17-5	C21H26Cl2F3N3S	1 g/5 g

• Phenoxybenzamine
  A cell-permeable, non-specific, irreversible α-adrenergic antagonist that inhibits calmodulin-stimulated phosphodiesterase activity.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-3581	63-92-3	C18H22ClNO··HCl	200 mg/1 g

• W-13 Isomer hydrochloride
  Isomer of W-13

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-222413	88519-57-7	C14H17ClN2O2S ·HCl	1 mg

• W-13 Isomer, Decyl Analog hydrochloride
  The most potent isomer of the naphthalenesulfonamide family of calmodulin inhibitors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-222414	79127-24-5	C20H29ClN2O2S ·HCl	5 mg

• W-5
  A calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201500	61714-25-8	C16H22N2O2S ·HCl	20 mg

• W-7
  Shown to be a cell permeable calmodulin antagonist that inhibits certain enzyme activities. Also has been reported to be an antiproliferative agent.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-201501	61714-27-0	C16H21ClN2O2S•HCl	50 mg