Calcium Channel Modulators

1-D-3-Deoxy-phosphatidylinositol
A putative antimetabolite of phosphatidylinositol-3-phospate that has been shown to act as a strong agonist in releasing calcium from saponin permeabilized SH-Sy5Y human neuroblastoma cells.
Katalog # CAS Nummer Summenformel Menge
sc-216117 n.n. C₄₁H₇₉O₁₂P 100 µg/1 mg
2',4'-Dichlorobenzamil • HCl
An inhibitor of Na⁺/Ca²⁺ exchanger protein (NCX). Inhibits whole-cell inward currents stimulated by 8-Br-cGMP at nucleotide-gated cation channels. Blocks caffeine-induced release of Ca²⁺ internal stores from olfactory neurons.
Katalog # CAS Nummer Summenformel Menge
sc-200197 1166-01-4 C₁₃H₁₂Cl₃N₇O•HCl 5 mg/25 mg
6-Benzylaminopurine
Plant cell division factor. Stimulates Ca²⁺ influx by moss protoplasts. Reportedly induces positive inotropic effects through activation of P2-purinergic receptors.
Katalog # CAS Nummer Summenformel Menge
sc-202428 1214-39-7 C₁₂H₁₁N₅ 1 g/5 g
9,21-Dehydroryanodine
A naturally occuring Ryanodine derivative that is shown to influence Ca²⁺ channels similar to Ryanodine.
Katalog # CAS Nummer Summenformel Menge
sc-291770 94513-55-0 C₂₅H₃₃NO₉ 1 mg
A 582941
Katalog # CAS Nummer Summenformel Menge
sc-362706 848591-90-2 C₁₇H₂₀N₄ 10 mg/50 mg
Adenosine 5'-[γ-thio]triphosphate tetralithium salt
A P2 purinergic agonist that has been shown to substitute for ATP as a kinase substrate, resulting in the formation of phospatase resistant thiophosphorlyated proteins.
Katalog # CAS Nummer Summenformel Menge
sc-214500 93839-89-5 C₁₀H₁₂Li₄N₅O₁₂P₃S 1 mg/5 mg
Amiloride • HCl
A selective T-type calcium channel blocker shown to inhibit Polycystin-L2 channels (PKD2L2), block epithelial sodium channels and serve as a potassium-sparing diuretic.
Katalog # CAS Nummer Summenformel Menge
sc-3578 2016-88-8 C₆H₈ClN₇O ·HCl 25 mg/100 mg
Amiodarone
Shown to inhibit binding of 1,4-dihydropyridine to L-type Ca2+ channels, a/b-adrenergic receptor antagonist, and coronary vasodilator.
Katalog # CAS Nummer Summenformel Menge
sc-291891 1951-25-3 C₂₅H₂₉I₂NO₃ ·HCl 250 mg/1 g
Amlodipine
A long-acting dihydropyridine calcium channel blocker. Amlodipine is a 3rd generation L-type calcium channel blocker with a unique spectrum of actions over and above its antihypertensive activity which include stimulation of NO synthase, inhibition of monocyte-endothelial adhesion, inhibition of oxidative stress and sustained duration of action.
Katalog # CAS Nummer Summenformel Menge
sc-200195 88150-42-9 C₂₀H₂₅ClN₂O₅ 100 mg/1 g
Amlodipine besylate
L-type calcium channel blocker. Has antihypertensive properties. Also displays vasoprotective effects in cardiovascular disease and inhibits Ca²⁺-induced contractions in depolarized rat aorta (IC₅₀ = 1.9 nM). Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC₅₀ = 25 μM).
Katalog # CAS Nummer Summenformel Menge
sc-203511 111470-99-6 C₂₀H₂₅ClN₂O₅ ·C₆H₆O₃S 50 mg
Azelnidipine
A novel dihydropyridine derivative, is a L-type calcium channel blocker and antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.
Katalog # CAS Nummer Summenformel Menge
sc-252395 123524-52-7 C₃₃H₃₄N₄O₆ 10 mg
(±)-Bay K 8644
Katalog # CAS Nummer Summenformel Menge
sc-203324 71145-03-4 C₁₆H₁₅F₃N₂O₄ 1 mg/5 mg/50 mg
BAY K 8644, S(-)-
A racemic mixture of Bay K 8644 that is shown to be an L-type Ca²⁺ channel agonist. Also shown to cause an increase in myosin light chain phosphorylation.
Katalog # CAS Nummer Summenformel Menge
sc-203525 98625-26-4 C₁₆H₁₅F₃N₂O₄ 10 mg/50 mg
BAY K8644 (+)
An analogue of nifedipine (sc-3589) that acts as a calcium ion channel agonist displaying positive inotropic activity by inducing Ca²⁺-dependent slow action potentials, enhancing the influx of Ca²⁺ into sarcolemma through myocardial slow channels.
Katalog # CAS Nummer Summenformel Menge
sc-201506 98791-67-4 C₁₆H₁₅F₃N₂O₄ 5 mg
Bepridil hydrochloride
A calcium channel antagonist that increases the surface area of red blood cells. Also a stomatocytic agent that causes endocytosis.
Katalog # CAS Nummer Summenformel Menge
sc-202974 74764-40-2 C₂₄H₃₄N₂O ·HCl 10 mg/25 mg
Caged Ca2+ channel antagonist
Katalog # CAS Nummer Summenformel Menge
sc-227563 154026-67-2 C₂₄H₂₃ClN₂O₆ 5 mg
Calcicludine II
Potent neurotoxin shown to preferentially block type L Ca2+ channels.
Katalog # CAS Nummer Summenformel Menge
sc-293976 178037-96-2 C₃₂₁H₄₇₆N₈₆O₇₈S₆ 70 µg
CAY10502
A potent Calcium-dependent cytosolic PLA2 (cPLA2α) inhibitor with an IC₅₀ value of 4.3 nM for the purified enzyme from human platelets. Inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC₅₀ values of 570 and 0.9 nM, respectively.
Katalog # CAS Nummer Summenformel Menge
sc-223866 n.n. C₃₀H₃₇NO₇ 500 µg/1 mg
CGP 37157
A benzothiazepine compound that is derived from clonazepam and described to act as a selective and potent inhibitor of mitochondrial Na⁺/Ca²⁺ exchange.
Katalog # CAS Nummer Summenformel Menge
sc-202097 75450-34-9 C₁₅H₁₁Cl₂NOS 5 mg
Cilnidipine
Dual L- / N-type calcium channel blocker. Displays renal and vascular protective effects in patients with essential hypertension. Displays neuroprotective effects in a rat focal brain ischemia model.
Katalog # CAS Nummer Summenformel Menge
sc-201485 132203-70-4 C₂₇H₂₈N₂O₇ 10 mg/50 mg
Cinnarizine
A calcium channel blocker with anti-histaminic, anti-allergic and anti-vasoconstricting activity.
Katalog # CAS Nummer Summenformel Menge
sc-211095 298-57-7 C₂₆H₂₈N₂ 100 mg
Dantrolene, Sodium Salt
An inhibitor of Ryanodine receptor-mediated Ca²⁺ flux. Presents muscle relaxant effects. Indicated as a neuroprotectant against glutamate excitotoxicity.
Katalog # CAS Nummer Summenformel Menge
sc-202124 14663-23-1 C₁₄H₉N₄O₅•Na 100 mg
Dantrolene, Sodium Salt Hemiheptahydrate
A muscle relaxant (skeletal). Used in the treatment of malignant hyperthermia.
Katalog # CAS Nummer Summenformel Menge
sc-218075 24868-20-0 2C₁₄H₉N₄NaO₅•7H₂O 100 mg
Diethyl Pyrocarbonate
Inhibits ryanodine binding to ryanodine/Ca²⁺ receptor channel in skeletal muscle, and could be useful for specific inactivation of nucleases.
Katalog # CAS Nummer Summenformel Menge
sc-202574 1609-47-8 C₆H₁₀O₅ 25 g/100 g
Diltiazem
Potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil.
Katalog # CAS Nummer Summenformel Menge
sc-204726 42399-41-7 C₂₂H₂₆N₂O₄S 1 g/5 g
Diltiazem • HCl
Selectively blocks the voltage-sensitive (L-type) calcium channel.
Katalog # CAS Nummer Summenformel Menge
sc-200199 33286-22-5 C₂₂H₂₆N₂O₄S··HCl 1 g/5 g
Dotarizine
A broad spectrum Ca²⁺ antagonist which blocks calcium uptake, [Ca²⁺]i rise and secretion via blockade of calcium channels.
Katalog # CAS Nummer Summenformel Menge
sc-203033 84625-59-2 C₂₉H₃₄N₂O₂ 5 mg/25 mg
Efonidipine hydrochloride
A selective blocker of L-type and T-type Ca2+ channels. Shown to display minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers displays different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity.
Katalog # CAS Nummer Summenformel Menge
sc-294464 111011-53-1 C₃₄H₃₈N₃O₇P ·HCl 10 mg/50 mg
Fasudil, Monohydrochloride Salt
A cell-permeable, selective ROCK inhibitor which induces neuroprotection in vitro.
Katalog # CAS Nummer Summenformel Menge
sc-203418 105628-07-7 C₁₄H₁₇N₃O₂S•HCl 10 mg/50 mg
Felodipine
A selective antagonist of the L-type (long-lasting) voltage-operated calcium channel. Selective for vascular tissue over myocardial tissue (100-fold selectivity). Blocks cytokine-induced NO and superoxide production.
Katalog # CAS Nummer Summenformel Menge
sc-201483 72509-76-3 C₁₈H₁₉Cl₂NO₄ 10 mg/50 mg
Fendiline hydrochloride
A coronary vasodilator.
Katalog # CAS Nummer Summenformel Menge
sc-239988 13636-18-5 C₂₃H₂₅N•HCl 5 g
Flunarizine • 2HCl
Shown to be a Ca²⁺ antagonist that inhibits contraction of isolated murine caudal artery preparations. Also has been reported to reduce the amounts of TXB2 and ALK-1.
Katalog # CAS Nummer Summenformel Menge
sc-201473 30484-77-6 C₂₆H₂₆F₂N₂··2HCl 1 g
FPL-64176
A potent L-type Ca²⁺ channel opener. Induces a contractile response in cardiac and vascular smooth muscle, EC₅₀=0.2 µM.
Katalog # CAS Nummer Summenformel Menge
sc-201491 120934-96-5 C₂₂H₂₁NO₃ 10 mg
G-15
High affinity and selective GPR30 receptor antagonist (Ki = 20 nM) that displays no affinity for ERα and ERβ at concentrations up to 10 μM. Has been shown to inhibit agonist-induced calcium mobilization in vitro (EC50 of ~185 nM) and antagonizes the antidepressive effects of estrogen in vivo.
Katalog # CAS Nummer Summenformel Menge
sc-294997 1161002-05-6 C₁₉H₁₆BrNO₂ 10 mg/50 mg
Gabapentin
A structurally similar GABA (γ-aminobutyric acid) analog which binds to a novel site on voltage-sensitive Ca²⁺ channels.
Katalog # CAS Nummer Summenformel Menge
sc-201481 60142-96-3 C₉H₁₇NO₂ 20 mg/100 mg
Heparin, Lithium Salt, Porcine Intestinal Mucosa
Highly sulfated dextrorotatory mucopolysaccharide with specific anticoagulant properties. Inhibits the endoplasmic reticulum IP3-activated Ca²⁺ release channel. Reported to also activate the ryanodine receptor. Note: 1 KU = 1000 units. Preservative-free, non-sterile.
Katalog # CAS Nummer Summenformel Menge
sc-203997 9045-22-1 n.n. 100 KU
Hepoxilin A3
An eicosanoid, which functions as an endogenous lipid mediator, inducing the release of intracellular calcium in human neutrophils.
Katalog # CAS Nummer Summenformel Menge
sc-221713 85589-24-8 C₂₀H₃₂O₄ 10 µg
Iberiotoxin
A highly selective and potent blocker of the high conductance Ca²⁺-activated K⁺ channels that does not affect other types of voltage-dependent K⁺ channels.
Katalog # CAS Nummer Summenformel Menge
sc-3585 129203-60-7 C₁₇₉H₂₇₄N₅₀O₅₅S₇ 10 µg/100 µg
Isradipine
A 2,4-dihydropyridine, selective agonist of L-type Ca²⁺ channels.
Katalog # CAS Nummer Summenformel Menge
sc-201467 75695-93-1 C₁₉H₂₁N₃O₅ 10 mg/50 mg
Kurtoxin
Kurtoxin is a compound found in scorpion toxin, and is a T-type Ca²⁺ channel blocker.
Katalog # CAS Nummer Summenformel Menge
sc-300858 n.n. C₃₂₄H₄₇₈N₉₄O₉₀S₈ 100 µg
L-651,582
Orally active Ca²⁺ channel blocker; inhibits K⁺ and carbachol-stimulated Ca²⁺ influx (IC₅₀ values are 500 and 935 nM respectively). Exhibits antiangiogenic, antiproliferative and antimetastatic activity in vivo and displays selectivity towards numerous mismatch repair-deficient tumor cell lines in vitro.
Katalog # CAS Nummer Summenformel Menge
sc-204039 99519-84-3 C₁₇H₁₂Cl₃N₅O₂ 10 mg/50 mg
L-cis-Diltiazem • HCl
Blocks cyclic nucleotide-gated calcium channels.
Katalog # CAS Nummer Summenformel Menge
sc-221802 42399-54-2 C₂₂H₂₆N₂O₄S•HCl 5 mg
L-Type Calcium Channel Blocker
A cell-permeable sulfonamide compound which reversibly interacts with the benzothiazepine-binding site as well as acts as a cardiac tissue selective L-type voltage gated Ca²⁺ channel activity inhibitor. It is shown to display negative chronotropic activity with minimal vasorelaxation.
Katalog # CAS Nummer Summenformel Menge
sc-221814 n.n. C₁₄H₁₉CLN₂O₂S 25 mg
Lanthanum(III) chloride heptahydrate
A Ca+ channel blocker.
Katalog # CAS Nummer Summenformel Menge
sc-211720 10025-84-0 LaCl₃ ·7H₂O 25 g/100 g
Lercanidipine hydrochloride
L-type Ca²⁺ channel blocker that displays higher vascular selectivity than Felodipine. Causes peripheral vasodilation with only weak negative inotropic activity. Also antihypertensive.
Katalog # CAS Nummer Summenformel Menge
sc-204054 132866-11-6 C₃₆H₄₁N₃O₆ ·HCl 10 mg/50 mg
Lercanidipine hydrochloride hemihydrate
An L-type (Cav1.2b) vascular channel antagonist. A cardiac channel agonist voltage-dependent and highly lipophylic compound that exhibits a slower onset and longer duration of action than other calcium channel antagonists. An antihypertensive agent in patients with mild-to-moderate hypertension.
Katalog # CAS Nummer Summenformel Menge
sc-252951 132866-11-6 (anhydrous) C₃₆H₄₁N₃O₆•HCl•0.5H₂O 10 mg
Lercanidipine-d3 (hydrochloride)
A calcium channel blocker of the dihydropyridine class.
Katalog # CAS Nummer Summenformel Menge
sc-221841 n.n. C₃₆H₃₈D₃N₃O₆•HCl 1 mg/5 mg
LOE 908 hydrochloride
Broad spectrum cation channel blocker; neuroprotective
Katalog # CAS Nummer Summenformel Menge
sc-204060 149759-26-2 (anhydrous) C₄₁H₄₈N₂O₉•HCl•xH₂O 10 mg/50 mg
Loperamide Hydrochloride
A high affinity μ-opioid receptor agonist. Demonstrates localized antihyperalgesic effects. Blocks Ca²⁺ flux through ion channels.
Katalog # CAS Nummer Summenformel Menge
sc-203116 34552-83-5 C₂₉H₃₃ClN₂O₂.HCl 5 g
Manidipine
A dihydropyridine Ca²⁺ channel blocker.
Katalog # CAS Nummer Summenformel Menge
sc-211774 89226-50-6 C₃₅H₃₈N₄O₆ 10 mg
Manidipine dihydrochloride
A third generation dihydropyridine calcium antagonist which casues systemic vasodilation by inhibiting the voltage dependent calcium inward currents in smooth muscle cells. Hypertension drug.
Katalog # CAS Nummer Summenformel Menge
sc-205739 89226-75-5 C₃₅H₃₈N₄O₆ 2HCl 25 mg/100 mg
(±)-Methoxyverapamil Hydrochloride
Phenethylamine derivative that functions as a Ca²⁺ channel blocker. Blocks maitotoxin-induced Ca²⁺ influx in 3T3 cells (IC₅₀ = 16 µM)
Katalog # CAS Nummer Summenformel Menge
sc-202706 16662-47-8 C₂₈H₄₀N₂O₅ ·HCl 25 mg
Mibefradil dihydrochloride
A nondihydropyridine antagonist which selectively blocks Ca²⁺ entry into cells by inhibiting T-type (low-voltage activated) Ca²⁺ channels.
Katalog # CAS Nummer Summenformel Menge
sc-204083 116644-53-2 C₂₉H₃₈FN₃O₃•xHCl•xH₂O 10 mg/50 mg
Midodrine, Hydrochloride
A phenylalkanolamine derivative which has been found to be effective in the treatment of hypertensive conditions due to their long lasting, blood pressure increasing effects.
Katalog # CAS Nummer Summenformel Menge
sc-211910 3092-17-9 C₁₂H₁₈N₂O₄ ·HCl 10 mg
MRS 1845
Potent blocker of store-operated Ca²⁺ channels and inhibits capacitative Ca²⁺ influx in HL-60 cells (IC₅₀ = 1.7 mM).
Katalog # CAS Nummer Summenformel Menge
sc-203636 544478-19-5 C₂₁H₂₂N₂O₆ 10 mg/50 mg
myo-Inositol 1,3,4,6-tetrakis-phosphate ammonium salt
An inositol tetrakisphosphate described to accumulate in angiotensin II-stimulated cells. Demonstrated to stimulate the mobilization of intracellular Ca²⁺ in SH-SY5Y cells.
Katalog # CAS Nummer Summenformel Menge
sc-215403 142507-74-2 C₆H₁₆O₁₈P₄ ·xNH₃ 50 µg
N-[4-[(2S)-3-[[2-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropoxy]phenyl]-methanesulfonamide
N-Methyl-D-aspartate (NMDA) receptors are Ca2+ permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. This chemical is a propanolamine that potently, selectively, and non-competitively antagonizes the NR2B subunit of NMDA receptors (IC50 = 50 nM). It does not inhibit NR1, NR2A, NR2C, and NR2D subunits and has no significant effects on α-amino-3-hydroxy-5-methyl-4-isoxazolepropioinic acid (AMPA) or kainate receptors. This compound is neuroprotective, since it prevents NMDA-triggered release of lactate dehydrogenase from cultured cortical neurons. Also, when administered intraperitoneally, reduces brain infarct volume resulting from transient ischemia via carotid artery occlusion.
Katalog # CAS Nummer Summenformel Menge
sc-295632 457897-92-6 C₁₈H₂₂Cl₂N₂O₄S 1 mg/5 mg
Nemadipine-A
A potent modulator of C. elegans growth. Targets the EGL-19 Ca²⁺ channel.
Katalog # CAS Nummer Summenformel Menge
sc-202727 54280-71-6 C₁₉H₁₈F₅NO₄ 5 mg
Nemadipine-B
Cell permeable antagonist of L-type Ca²⁺ channels in C. elegans.
Katalog # CAS Nummer Summenformel Menge
sc-203157 79925-38-5 C₁₉H₂₁Cl₂NO₄ 5 mg
Nicardipine hydrochloride
A potent L-type Ca²⁺ channel blocker. Alters CYP3A expression. Demonstrates antihypertensive effects.
Katalog # CAS Nummer Summenformel Menge
sc-202731 54527-84-3 C₂₆H₂₉N₃O₆•HCl 1 g/5 g
Nifedipine
Selectively blocks L-type voltage-sensitive calcium channels; vasodilator. Induces apoptosis in human glioblastoma cells.
Katalog # CAS Nummer Summenformel Menge
sc-3589 21829-25-4 C₁₇H₁₈N₂O₆ 250 mg/5 g
Niguldipine • HCl
A highly selective α ₁-adrenoceptor antagonist and dihydropyridine calcium channel blocker. Also been noted to inhibit noradrenaline-stimulated inositol phosphate accumulation.
Katalog # CAS Nummer Summenformel Menge
sc-201471 113317-61-6 C₃₆H₃₉N₃O₆ ·HCl 10 mg/50 mg
Nimodipine
A dihydropyridine-type voltage-sensitive (L-type) calcium channel blocker.
Katalog # CAS Nummer Summenformel Menge
sc-201464 66085-59-4 C₂₁H₂₆N₂O₇ 100 mg/1 g
Nitrendipine
A dihydropyridine-type voltage-sensitive (L-type) calcium channel blocker. Modulates NMDA receptor channel function in mammalian neurons . Inhibits neutrophil adhesion to vascular endothelium.
Katalog # CAS Nummer Summenformel Menge
sc-201466 39562-70-4 C₁₈H₂₀N₂O₆ 50 mg
NNC 55-0396
A nonhydrolyzable analog of Mibefradil which functions as a selective T-type Ca²⁺ channel inhibitor.
Katalog # CAS Nummer Summenformel Menge
sc-203647 357400-13-6 C₃₀H₃₈FN₃O₂•2HCl 10 mg
NNC 55-0396 hydrate
This product is a selective T-type calcium channel inhibitor.
Katalog # CAS Nummer Summenformel Menge
sc-301481 357400-13-6 C₃₀H₄₀Cl₂FN₃O₂•xH₂O 5 mg
PD 173212
N-type voltage-gated Ca²⁺ channel blocker. Selective of K⁺, Na⁺, and L-type Ca²⁺ channels. In vivo, prevents tonic seizures in the audiogenic seizure model.
Katalog # CAS Nummer Summenformel Menge
sc-204169 217171-01-2 C₃₈H₅₃N₃O₃ 10 mg
Penfluridol
Katalog # CAS Nummer Summenformel Menge
sc-255410 26864-56-2 C₂₈H₂₇ClF₅NO 50 mg
Pranidipine
A novel calcium channel antagonist as well as a cardiovascular agent.
Katalog # CAS Nummer Summenformel Menge
sc-212579 99522-79-9 C₂₅H₂₄N₂O₆ 10 mg
Protopine hydrochloride
A light-sensitive Ca²⁺ channel blocker and antiplatelet agent.
Katalog # CAS Nummer Summenformel Menge
sc-272121 6164-47-2 C₂₀H₁₉NO₅··HCl 5 mg
Pyr3
A pyrazole compound that potently and selectively antagonizes TRPC3. Pyr3 inhibits TRPC3 by binding to the extracellular side of the receptor, resulting in suppression of B cell activation and cardiac hypertrophy. Members of the canonical transient receptor potential (TRPC) channel family are ion channels which conduct Ca+2 and are activated by membrane receptor-mediated stimulation of phospholipase C (PLC) activity. However, TRPC3 and other family members are also activated by membrane-independent diacylglycerol (DAG). BTP1 and BTP2 are pyrazoles that block TRPC channels, but they are not specific for TRPC subtypes. This channel is implicated in various processes, including B cell receptor (BCR)-mediated Ca+2 oscillations, activation of nuclear factor of activated T cells (NFAT), and promotion of cardiac hypertrophy.
Katalog # CAS Nummer Summenformel Menge
sc-301624 1160514-60-2 C₁₆H₁₁Cl₃F₃N₃O₃ 5 mg
(R)-(+)-Felodipine
Enantiomer
Katalog # CAS Nummer Summenformel Menge
sc-212658 119945-59-4 C₁₈H₁₉Cl₂NO₄ 1 mg
Repaglinide
Non-sulfonylurea oral hypoglycemic agent. Used as an antidiabetic.
Katalog # CAS Nummer Summenformel Menge
sc-219959 135062-02-1 C₂₇H₃₆N₂O₄ 100 mg
S-Petasin
A L-type voltage-dependent calcium channel blocker.
Katalog # CAS Nummer Summenformel Menge
sc-253449 70238-51-6 C₁₉H₂₆O₃S 1 mg
(S)-(-)-Felodipine
Enantiomer
Katalog # CAS Nummer Summenformel Menge
sc-212833 105618-03-9 C₁₈H₁₉Cl₂NO₄ 1 mg
SDZ-202 791 R(-)
A dihydropyridine-type voltage-sensitive (L-type) calcium channel blocker.
Katalog # CAS Nummer Summenformel Menge
sc-201474 97217-84-0 C₁₇H₁₈N₄O₅ 1 mg
SK&F 96365
Inhibitor of receptor-mediated calcium entry. Note, in some cells SK&F 96365 can activate a novel Ca²⁺ entry pathway. Blocks TRPC3 and TRPC6 activation.
Katalog # CAS Nummer Summenformel Menge
sc-201475 130495-35-1 C₂₂H₂₆N₂O₃··HCl 5 mg/25 mg
SN-6
Selective Na+/Ca2+-exchange (NCX) inhibitor; displays some selectivity for NCX1; Anti-ischemic.
Katalog # CAS Nummer Summenformel Menge
sc-203698 415697-08-4 C₂₀H₂₂N₂O₅S 10 mg/50 mg
SR 33805 oxalate
Potent Ca²⁺ channel blocker; binds allosterically to a1-subunit of L-type Ca²⁺ channels (K_d = 20 pM), at a site distinct from other types of blocker. Shows some selectivity for vascular smooth muscle, inducing vasorelaxation without producing inotropic or chronotropic effects. Inhibits PDGF-stimulated smooth muscle cell proliferation.
Katalog # CAS Nummer Summenformel Menge
sc-204299 121346-32-5 C₃₂H₄₀N₂O₅S.C₂H₂O₄ 10 mg
TCS 5861528
Katalog # CAS Nummer Summenformel Menge
sc-361378 332117-28-9 C₁₉H₂₃N₅O₃ 10 mg/50 mg
Tetrahydropalmatine hydrochloride
Voltage-dependent Ca²⁺ channel inhibitor.
Katalog # CAS Nummer Summenformel Menge
sc-296504 6024-85-7 C₂₁H₂₆ClNO₄ 1 mg
Tetrandrine
Bis-coclaurine alkaloid used for centuries in Chinese traditional medicine for cardiovascular diseases. Blocks the L-type and T-type calcium channels. Blocks Ca²⁺-activated K⁺ channel.
Katalog # CAS Nummer Summenformel Menge
sc-201492 518-34-3 C₃₈H₄₂N₂O₆ 50 mg/250 mg
Thionicotinamide adenine dinucleotidephosphate sodium salt
Blocks nicotinate adenine dinucleotide phosphate (NAADP)-induced Ca²⁺ release.
Katalog # CAS Nummer Summenformel Menge
sc-253695 19254-05-8 C₂₁H₂₇N₇O₁₆P₃S ·Na 10 mg
trans Lacidipine
A dihydropyridine calcium channel blocker. Structurally characterized by its cinnamate moiety, which results in specific photochemical properties that differ from other dihydropyridine.
Katalog # CAS Nummer Summenformel Menge
sc-213066 103890-78-4 C₂₆H₃₃NO₆ 10 mg
trans-Ned 19
Katalog # CAS Nummer Summenformel Menge
sc-362814 n.n. C₃₀H₃₁FN₄O₃ 10 mg
Verapamil Ethyl Methanethiosulfonate, Bromide
An analog of Verapamil.
Katalog # CAS Nummer Summenformel Menge
sc-208483 353270-25-4 C₃₀H₄₅BrN₂O₆S₂ 5 mg
w-Grammotoxin SIA
A potent inhibitor of Cav2.1 (P-type) and Cav2.2 (N-type) channels.
Katalog # CAS Nummer Summenformel Menge
sc-251432 152617-90-8 C₁₇₇H₂₆₈N₅₂O₅₀S₆ 5 µg
ω-Agatoxin TK
Peptide toxin from the funnel web spider Agelenopsis aperta. Selective blocker of the P-type Ca²⁺ channel. Blocks a Q-type-like Ca²⁺ channel with low sensitivity.
Katalog # CAS Nummer Summenformel Menge
sc-200190 158484-42-5 C₂₁₅H₃₃₇N₆₅O₇₀S₁₀ 50 µg
Xestospongin D, Xestospongia sp.
This is a reversible, membrane-permeable blocker of IP3-mediated Ca²⁺release (IC₅₀ = 648 nM). It displays high selectivity over the skeletal isoform of the ryanodine receptor type 1 (RyR-1).
Katalog # CAS Nummer Summenformel Menge
sc-222422 n.n. C₂₈H₅₀N₂O₃ 50 µg
Ziconotide Acetate
A selective antagonist of N-type voltage sensitive calcium channels (VSCC). It blocks neurotransmitter release by preventing depolarization-induced calcium influx. It is also used as a ligand for binding studies of voltage sensitive calcium channels.
Katalog # CAS Nummer Summenformel Menge
sc-213176 914454-03-8 C₁₀₄H₁₇₆N₃₆O₃₄S₇ 0.25 mg
Zonisamide
Blocks voltage-sensitive Na⁺ and T-type Ca²⁺ channels, stimulates BKCa channels and modulates GABA.
Katalog # CAS Nummer Summenformel Menge
sc-203316 68291-97-4 C₈H₈N₂O₃S 10 mg/50 mg