Antioxidants and Free Radical Scavengers

1-O-Hexyl-2,3,5-trimethylhydroquinone
A novel phenolic antioxidant that shows strong antimutagenic activity against eight carcinogenic heterocyclic amines (HCA) produced during cooking processes. The antimutagenic activity appeared to inhibit metabolic activation of HCA.
Katalog # CAS Nummer Summenformel Menge
sc-206192 148081-72-5 C₁₅H₂₄O₂ 100 mg
1,3-dichloro-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene
The aryl hydrocarbon receptor (AhR) is an intracellular ligand-dependent transcription factor whose ligands include some of the most infamous xenobiotics, including benzo[a]pyrene, dioxin (TCDD, 2,3,7,8-tetrachlorodibenzoparadioxin) and numerous polyaromatic hydrocarbons from coal tar and soot particles. This chemical is a potent and selective antagonist of AhR, with a Ki of 1.4 nM when tested in rabbit liver cytosol. It is inactive as an estrogen receptor ligand even at 100 µM.
Katalog # CAS Nummer Summenformel Menge
sc-220545 688348-37-0 C₁₅H₁₂Cl₂O 10 mg/25 mg
3-Carboxy-2,2,5,5-tetramethyl-1-pyrrolidine-1-oxyl, free radical
Free radical compound.
Katalog # CAS Nummer Summenformel Menge
sc-202415 2154-68-9 C₉H₁₆NO₃ 10 mg/50 mg
3-tert-Butyl-4-hydroxyanisole
Antioxidant used to stabilize fatty food. It was found to inhibit chemically-induced tumor formation in animals. Under high dose conditions it was carcinogenicto the forestomach of rodents.
Katalog # CAS Nummer Summenformel Menge
sc-204621 121-00-6 C₁₁H₁₆O₂ 10 g/50 g
3,4',5-Trismethoxybenzophenone
A potent phenolic antioxidant that has antiproliferative properties. Cell growth inhibition is enhanced when the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers. It is an analog of trismethoxy resveratrol. It inhibits the growth of a variety of human tumor cell lines at concentrations from 0.4 to 2 µg/ml, which is almost six times more potent than resveratrol.
Katalog # CAS Nummer Summenformel Menge
sc-204625 94709-12-3 C₁₆H₁₆O₄ 10 mg/25 mg
3,5-Di-O-caffeoylquinic acid
Antioxidant. Shows antiproliferative activity.
Katalog # CAS Nummer Summenformel Menge
sc-202418 2450-53-5 C₂₅H₂₄O₁₂ 1 mg
15-Lipoxygenase Inhibitor I
A heterocyclic pyrimidobenzothiazine compound with an IC₅₀ value of 18 μM.
Katalog # CAS Nummer Summenformel Menge
sc-220625 928853-86-5 C₁₆H₁₉N₅S 500 µg/1 mg
AFMK
A melatonin metabolite identified in rat brain. Have displayed antioxidant and free radical scavenging activities in several models. May be measured in plasma as an index of melatonin synthesis and metabolism.
Katalog # CAS Nummer Summenformel Menge
sc-205201 52450-38-1 C₁₃H₁₆N₂O₄ 1 mg/5 mg
Allicin
A compound found in garlic that has been shown to inhibit telomerase activity and act as an antioxidant.
Katalog # CAS Nummer Summenformel Menge
sc-202449 539-86-6 C₆H₁₀OS₂ 1 mg/5 mg
α-Lipoic Acid
A metabolic antioxidant that regulates NF-κB signal transduction and can protect against oxidative injury.
Katalog # CAS Nummer Summenformel Menge
sc-202032 1077-28-7 C₈H₁₄O₂S₂ 5 g
Ambroxol hydrochloride
An expectorant and mucolytic agent. Demonstrates antioxidant and antiinflammatory effects. Scavenger of hydroxyl radicals and superoxide radical anions.
Katalog # CAS Nummer Summenformel Menge
sc-200816 23828-92-4 C₁₃H₁₈Br₂N₂O•HCl 1 g
AMVN
Katalog # CAS Nummer Summenformel Menge
sc-205206 4419-11-8 C₁₄H₂₄N₄ 100 mg/500 mg
AN-7
A more lipophilic analog of α-lipoic acid with enhanced potency and a 1.5-fold increased maximal capacity to stimulate glucose transport into myocytes.2 This identifies lipoic acid analogs as potential new treatments for diabetes.
Katalog # CAS Nummer Summenformel Menge
sc-221251 691410-93-2 C₁₉H₃₄N₂O₂S₄ 5 mg/10 mg
Apocynin
A methoxy-subsituted catechol that is commonly used as an inhibitor of NADPH oxidase.
Katalog # CAS Nummer Summenformel Menge
sc-203321 498-02-2 C₉H₁₀O₃ 1 g
Astaxanthin
A powerful carotenoid antioxidant with cell-protective, anti-inflammatory, and anti-neoplastic properties.
Katalog # CAS Nummer Summenformel Menge
sc-202473 472-61-7 C₄₀H₅₂O₄ 50 mg/250 mg
Baicalin
A flavonoid compound with anti-inflammatory and anti-oxidant activity extracted from Scutellarua rivularis.
Katalog # CAS Nummer Summenformel Menge
sc-204638 21967-41-9 C₂₁H₁₈O₁₁ 1 mg/5 mg
Bakuchiol
Antioxidant. Inhibitor of PTB1B, mitochondrial lipid peroxidation, iNOS expression and DNA polymerase. Shows antimicrobial and cytotoxic activity.
Katalog # CAS Nummer Summenformel Menge
sc-202075 10309-37-2 C₁₈H₂₄O 1 mg
Bavachin
Weak antioxidant. Antimutagenic. Stimulates bone formation and has potential activity against osteoporosis. Shows inhibitory activities against the antigen-induced degranulation.
Katalog # CAS Nummer Summenformel Menge
sc-202489 19879-32-4 C₂₀H₂₀O₄ 500 µg
Bilirubin
Principal pigment of bile and a major end product of hemoglobin decomposition. Has conjugated double bonds and reactive hydrogen atoms. Serves as a physiological antioxidant.
Katalog # CAS Nummer Summenformel Menge
sc-202499 635-65-4 C₃₃H₃₆N₄O₆ 1 g
Butylated hydroxytoluene (BHT)
An antioxidant shown to be chemopreventive against a variety of carcinogens. Low doses have a modulating effect on liver and bladder carcinogenesis.
Katalog # CAS Nummer Summenformel Menge
sc-204659 128-37-0 C₁₅H₂₄O 100 g/500 g
Caffeic acid methyl ester
Displays antioxidant, antiproliferative and cytotoxic properties. Ornithine decarboxylase and protein tyrosine kinases inhibitors. Strong inhibitory effect on human platelet aggregation.
Katalog # CAS Nummer Summenformel Menge
sc-204664 3843-74-1 C₁₀H₁₀O₄ 50 mg
Canthaxanthin
An antioxidant that suppresses cell proliferation in oral cancer cells.
Katalog # CAS Nummer Summenformel Menge
sc-205617 514-78-3 C₄₀H₅₂O₂ 5 g/10 g
Carazostatin
Antioxidant. Free radical scavenger. Potent inhibitor of lipid peroxidation.
Katalog # CAS Nummer Summenformel Menge
sc-202517 126168-32-9 C₂₀H₂₅NO 100 µg/1 mg
Carcinine ditrifluoroacetate
Katalog # CAS Nummer Summenformel Menge
sc-361133 56897-53-1 C₈H₁₄N₄O•2CF₃COH•xH₂O 50 mg
Carnosic acid
A diterpenoid that acts as an effective lipid peroxidation inhibitor in liposomal and microsomal environments, with antioxidant properties.
Katalog # CAS Nummer Summenformel Menge
sc-202520 3650-09-7 C₂₀H₂₈O₄ 10 mg/50 mg
Carnosine
Antioxidant. Inhibits soluble guanylyl cyclase (sGC) by interacting with the heme iron to form a chelate complex.
Katalog # CAS Nummer Summenformel Menge
sc-202521 305-84-0 C₉H₁₄N₄O₃ 1 g
Carnosol
Naturally occurring phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, and anticarcinogen. Shown to inhibit inductions of COX-2 by blocking PKC signaling.
Katalog # CAS Nummer Summenformel Menge
sc-204672 5957-80-2 C₂₀H₂₆O₄ 1 mg/5 mg
(±)-Catechin
Antioxidant flavonoid. Free radical scavenger. Has chemopreventive and antitumor properties.
Katalog # CAS Nummer Summenformel Menge
sc-202986 7295-85-4 C₁₅H₁₄O₆ 1 g
(-)-Catechin
Katalog # CAS Nummer Summenformel Menge
sc-234288 18829-70-4 C₁₅H₁₄O₆ 5 mg
(-)-Catechin gallate
An antioxidant constituent of green tea. At µM concentrations, inhibits VEGF-induced tyrosine phosphorylation. Also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is believed to play a role in the etiology of breast cancer.
Katalog # CAS Nummer Summenformel Menge
sc-252549 130405-40-2 C₂₂H₁₈O₁₀ 1 mg
(+)-Catechin (hydrate)
A more potent antioxidant than ascorbate or α-tocopherol in certain in vitro assays of lipid peroxidation. inhibits the free radical-induced oxidation of isolated LDL by AAPH(2) and has also been reported to act as an inhibitor of COX-1.
Katalog # CAS Nummer Summenformel Menge
sc-204673 88191-48-4 C₁₅H₁₄O₆ ·H₂O 1 g/5 g
(+)-Catechin monohydrate
An antioxidant flavonoid that is a free radical scavenger that is nontoxic to cells a high doses.
Katalog # CAS Nummer Summenformel Menge
sc-202523 225937-10-0 C₁₅H₁₄O₆ ·H₂O 1 g
CAY10512
NF-κB has a regulatory effect on the expression of numerous genes involved in immunity and inflammation, growth, cellular stress responses, and apoptosis. This chemical is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity.
Katalog # CAS Nummer Summenformel Menge
sc-205237 139141-12-1 C₁₅H₁₃FO 10 mg/100 mg
Chlorophyllin sodium copper salt
Katalog # CAS Nummer Summenformel Menge
sc-227637 11006-34-1 C₃₄H₃₁CuN₄Na₃O₆ 5 g
Cinnamtannin B-1
A-type proanthocyanidin contained in several plant species. Potent antioxidant. Protective agent against oxidative stress and apoptosis.
Katalog # CAS Nummer Summenformel Menge
sc-202997 88082-60-4 C₄₅H₃₆O₁₈ 5 mg
cis-Resveratrol
A potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. Blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase and also inhibits production of nitric oxide.
Katalog # CAS Nummer Summenformel Menge
sc-205254 61434-67-1 C₁₄H₁₂O₃ 5 mg/10 mg
cis-trismethoxy Resveratrol
A potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells; inhibits tubulin polymerization in a dose-dependent manner.
Katalog # CAS Nummer Summenformel Menge
sc-205255 94608-23-8 C₁₇H₁₈O₃ 10 mg/50 mg
Coenzyme Q10
An electron transport chain component of the mitochondria, which assists proton and electron transfer across the inner mitochondrial membrane.
Katalog # CAS Nummer Summenformel Menge
sc-205262 303-98-0 C₅₉H₉₀O₄ 10 mg/50 mg
Cyanidin chloride
A polyphenolic anthocyanin, demonstrates antioxidant and cell protective effects. Presents an antiproliferative effect through blockade of AP-1 activation.
Katalog # CAS Nummer Summenformel Menge
sc-202559 528-58-5 C₁₅H₁₁ClO₆ 10 mg/50 mg
Cyclo-Gly-Pro
A neuro-protective compound, an endogenous diketopiperazine, which enhances memory. In the animal model of PD, this compound improved functional recovery when administered after the onset of dyskinesia. It appears that the compound recovery function may result from non-proliferative neurogenesis that results from the inhibition of apoptosis of stem cells and/or the promotion of neuronal-orientated proliferation in the subventricular zone (SVZ).
Katalog # CAS Nummer Summenformel Menge
sc-252644 3705-27-9 C₇H₁₀N₂O₂ 10 mg
Cysteamine, Hydrochloride
An inhibitor of DMBA-induced mammary tumors; used as an antioxidant and in radiation therapy.
Katalog # CAS Nummer Summenformel Menge
sc-205642 156-57-0 C₂H₇NS.HCl 25 g/100 g
Daphnetin
A coumarin analog that acts as an inhibitor of several protein kinases (EGFR kinase, PKA and PKC).
Katalog # CAS Nummer Summenformel Menge
sc-203022 486-35-1 C₉H₆O₄ 10 mg
Delphinidin chloride
Anthocyanidin with antioxidant effect found in pigmented fruits and vegetables. Shown to inhibit angiogenesis and endothelial cell apoptosis by stimulating nitric oxide (NO) production. Inhibits solar radiation (UVB)-mediated oxidative stress, reducing DNA damage.
Katalog # CAS Nummer Summenformel Menge
sc-202572 528-53-0 C₁₅H₁₁ClO₇ 10 mg
δ-Tocotrienol
Significantly suppresses H2O2-induced cell death of rat striatal neurons and provides protection against S-nitrocysteine-induced cell death and SIN-1 cytotoxicity in a concentration dependant manner.
Katalog # CAS Nummer Summenformel Menge
sc-205547 25612-59-3 C₂₇H₄₀O₂ 1 mg/5 mg
Dihydrocapsaicin
Katalog # CAS Nummer Summenformel Menge
sc-202578 19408-84-5 C₁₈H₂₉NO₃ 10 mg/50 mg
dimethoxy Curcumin
Phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells. An analog of curcumin, dimethoxy Curcumiin, was obtained by the methylation of both free phenolic groups in the parent compound. With this addition, a 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells.
Katalog # CAS Nummer Summenformel Menge
sc-205217 160096-59-3 C₂₃H₂₄O₆ 1 mg/5 mg
DMNQ
Cell-permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Used to eliminate mechanistic ambiguity involving redox cycling quinoids as the source of ROS/oxidative stress.
Katalog # CAS Nummer Summenformel Menge
sc-202586 6956-96-3 C₁₂H₁₀O₄ 10 mg
DPPH, Free Radical
Cell-permeable, stable free radical that is a hydrogen radical scavenger. Induces free-radical injury to tissues. Used in screens for detecting free radical scavenging activity of antioxidants.
Katalog # CAS Nummer Summenformel Menge
sc-202591 1898-66-4 C₁₈H₁₂N₅O₆ 50 mg
Ebselen Oxide
Ebselen is used for the treatment of cerebral infarctions and is an excellent scavenger of peroxynitrite. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, which indicats that it can serve as a negative control for ebselen.
Katalog # CAS Nummer Summenformel Menge
sc-223958 104473-83-8 C₁₃H₉NO₂Se 1 mg/5 mg
Ellagic Acid, Dihydrate
A cell permeable compound that acts as a strong CK2 inhibitor, potent antioxidant, and anti-mutagenic.
Katalog # CAS Nummer Summenformel Menge
sc-202598 476-66-4 C₁₄H₆O₈ ·2H₂O 500 mg
(-)Epicatechin
Katalog # CAS Nummer Summenformel Menge
sc-205672 490-46-0 C₁₅H₁₄O₆ 1 mg/5 mg
Erdosteine
A homocysteine-derived expectorant which undergoes metabolic conversion to produce a thiol containing compound that has free radical scavenging and mucolytic activity.
Katalog # CAS Nummer Summenformel Menge
sc-205678 84611-23-4 C₈H₁₁NO₄S₂ 100 mg/500 mg
Esculin Hydrate
Antioxidant used as a skin protectant. Displays vitamin P activity. Protects cells against DNA damage and reduces ROS levels. Carcinogenesis inhibitor.
Katalog # CAS Nummer Summenformel Menge
sc-204744 531-75-9 C₁₅H₁₆O₉ ·H₂O 5 g
Ethoxyquin
A synthetic antioxidant which inhibits chemically induced carcinogenesis, where it exerts its chemopreventive action by inducing glutathione synthetase and the phase II drug metabolizing enzyme, glutathione S-transferase (GST).
Katalog # CAS Nummer Summenformel Menge
sc-205686 91-53-2 C₁₄H₁₉NO 100 g/250 g
EUK 118
A structural analog of EUK 8 and EUK 134 with significantly reduced activity and exhibiting a catalase activity.
Katalog # CAS Nummer Summenformel Menge
sc-205319 186299-34-3 C₂₂H₂₅MnN₂O₈ 5 mg/50 mg
EUK 124
EUK 124 is a structural analog of EUK 8 and EUK 134 but with significantly reduced activity. EUK 124 and EUK 8 inhibit superoxide-mediated reduction of an electron acceptory.2
Katalog # CAS Nummer Summenformel Menge
sc-205320 186299-35-4 C₂₀H₂₂ClMnN₂O₆ 5 mg/10 mg
EUK 134
Act as a scavenger for oxidative species such as hydrogen peroxide, peroxynitrite and superoxide.
Katalog # CAS Nummer Summenformel Menge
sc-205321 81065-76-1 C₁₈H₁₈ClMnN₂O₄ 5 mg/10 mg
Formononetin
Phytoestrogenic isoflavone found in soy-based foods with potent antioxidant properties. Selective inhibitor of the g-isoform of alcohol dehydrogenase. Induces mammary gland proliferation in mice.
Katalog # CAS Nummer Summenformel Menge
sc-202614 485-72-3 C₁₆H₁₂O₄ 5 mg
Galvinoxyl, free radical
Free radical compound.
Katalog # CAS Nummer Summenformel Menge
sc-202620 2370-18-5 C₂₉H₄₁O₂ 10 mg/50 mg
(-)-Gallocatechin gallate
Antioxidant
Katalog # CAS Nummer Summenformel Menge
sc-252849 4233-96-9 C₂₂H₁₈O₁₁ 5 mg
(-)-Gallocatechin
This chemical possesses free radical scavenging ability. It inhibits the growth and adherence of P. gingivalis onto the buccal epithelial cells. A olyphenolic compound found in green tea and an epimer of (-)-epigallocatechin.
Katalog # CAS Nummer Summenformel Menge
sc-252848 3371-27-5 C₁₅H₁₄O₇ 1 mg
γ-CEHC
The major tocopherol obtained from natural dietary sources is γ-tocopherol, whereas α-tocopherol is the form of Vitamin E typically obtained from synthetic supplements. γ-CEHC is a β-oxidized metabolite of dietary γ-tocopherol that functions as a natriuretic hormone. It was initially characterized and purified from the urine of uremic patients, but it has since been found in urine from both those with congestive heart failure and control patients. γ-CEHC is also anti-inflammatory, reducing 8-isoprostane and inflammatory eicosanoid synthesis in rat models.
Katalog # CAS Nummer Summenformel Menge
sc-223880 178167-75-4 C₁₅H₂₀O₄ 1 mg/5 mg
γ-Tocotrienol
Recent studies have shown that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.
Katalog # CAS Nummer Summenformel Menge
sc-205529 14101-61-2 C₂₈H₄₂O₂ 1 mg/10 mg
GERI-BP002-A
A novel inhibitor of Acyl-CoA Cholesterol Acyltransferase (ACAT) which is produced by Aspergillus fumigatus F93. This compound also exhibits antioxidant activity.
Katalog # CAS Nummer Summenformel Menge
sc-221667 119-47-1 C₂₃H₃₂O₂ 100 mg/1 g
Glutathione Monoethyl Ester
Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH-MEE has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. A protective agent against cellular damage such as in cataracts and mitochondrial degeneration.
Katalog # CAS Nummer Summenformel Menge
sc-203974 118421-50-4 C₁₂H₂₁N₃O₆S 50 mg
Glutathione, reduced
GSH is the predominant non-protein thiol in animal tissues and in many physiological fluids; antioxidant; posseses several metabolic, regulatory, and protective functions.
Katalog # CAS Nummer Summenformel Menge
sc-29094 70-18-8 C₁₀H₁₇N₃O₆S 10 g/1 kg
Guaiacol
A phenolic natural product which serves a reducing co-substrate for COX reactions.
Katalog # CAS Nummer Summenformel Menge
sc-205337 90-05-1 C₇H₈O₂ 25 g/100 g
(±)-Hesperetin
Antioxidant flavonoid. Induces G1-phase cell cycle arrest. Anti-inflammatory. Suppresses NF-κB activation. Reduces cholesterol biosynthesis. Inhibits lipid peroxidation.
Katalog # CAS Nummer Summenformel Menge
sc-202647 520-33-2 C₁₆H₁₄O₆ 1 g
Hydrocortisone 21-acetate
A corticosteroid with anti-inflammatory properties. May stimulate superoxide dismutase production. And also may release antioxidants.
Katalog # CAS Nummer Summenformel Menge
sc-205715 50-03-3 C₂₃H₃₂O₆ 1 g/5 g
Idebenone
An anti-oxidant and neuroprotective agent. Has been reported to prevent platelet aggregation and increase nerve growth factor production in murine models.
Katalog # CAS Nummer Summenformel Menge
sc-200819 58186-27-9 C₁₉H₃₀O₅ 20 mg/100 mg
Isorhamnetin
Antiviral agent. Antioxidant. Antitumor compound. Apoptosis inducer.
Katalog # CAS Nummer Summenformel Menge
sc-202668 480-19-3 C₁₆H₁₂O₇ 5 mg/10 mg
L-(+)-Ergothioneine
Natural amino acid and antioxidant with Y and UV radiation-protective proerties obtained from the fungus Claviceps purpurea.
Katalog # CAS Nummer Summenformel Menge
sc-269284 58511-63-0 n.n. 5 mg
L-Ergothioneine
Has the ability to scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q10 or idebenone.
Katalog # CAS Nummer Summenformel Menge
sc-200814 497-30-3 C₉H₁₅N₃O₂S 10 mg/50 mg
Luteolin
Antioxidant flavonoid and free radical scavenger. Inhibits rat liver cytosolic glutathione S-transferase activity.
Katalog # CAS Nummer Summenformel Menge
sc-203119 491-70-3 C₁₅H₁₀O₆ 5 mg/50 mg
LY 231617
A potent antioxidant that readily crosses the blood-brain barrier, reduces ischemia-induced or hydrogen peroxide-induced neuronal damage and prevents activated NF-kB in hippocampal neurons.
Katalog # CAS Nummer Summenformel Menge
sc-204062 141545-89-3 C₁₇H₂₉NO ·HCl 5 mg
Lycopene
An open chain unsaturated carotenoid that gives tomatoes, guava, rose hip, watermelon and pink grapefruit its red color. Studies show that lycopene intake is significantly associated with lower risk of lung, colon and stomach carcinogenesis. It is an antioxidant that appears to have cancer chemopreventive properties, and helps AIDS patients.
Katalog # CAS Nummer Summenformel Menge
sc-205738 502-65-8 C₄₀H₅₆ 1 mg/5 mg
Malvidin chloride
An antioxidant flavonoid which induces cell cycle arrest in the G2/M-phase.
Katalog # CAS Nummer Summenformel Menge
sc-205952 643-84-5 C₁₇H₁₅O₇Cl 10 mg
Matairesinol
Principle lignans present in dietary fiber. Metabolized by enteric bacteria to enterolactone and enterodiol. Displays an inverse association between serum enterolactone levels and serum isoprostane levels. This implies a protective effect against oxidative injury associated with the dietary lignans themselves, enterolactone, or some intermediate in this pathway.
Katalog # CAS Nummer Summenformel Menge
sc-205379 580-72-3 C₂₀H₂₂O₆ 1 mg/5 mg
MCI-186
A free radical scavenger with protective properties towards murine neuronal ischemia. Found to enhance NGF protein levels via the JNK pathway.
Katalog # CAS Nummer Summenformel Menge
sc-200806 89-25-8 C₁₀H₁₀N₂O 500 mg/1 g
Melatonin
The endogenous neurohormone regulator of circadian rhythm and the sleep-wake cycle. Demonstrates powerful antioxidant activity. Upregulates the expression of antioxidant enzymes.
Katalog # CAS Nummer Summenformel Menge
sc-207848 73-31-4 C₁₃H₁₆N₂O₂ 1 g
Methimazole
An antithyroid compound used to treat Graves' hyperthyroidism. Found to have antioxidant property. Inhibits activation of the IFN-g-induced Janus kinase (JAK)/STAT signaling pathwayin FRTL-5 thyroid cells, which may account for its immunodolulatory effects.
Katalog # CAS Nummer Summenformel Menge
sc-205747 60-56-0 C₄H₆N₂S 10 g/25 g
MitoPBN
This is a nitrone antioxidant derived from IBTP, which blocks superoxide-induced lipid peroxidation in rat liver mitochondrial preparations without disrupting normal mitochondrial functions when used at concentrations that are below 25 µM. It selectively and rapidly traps carbon-centered secondary radicals, but is unreactive towards superoxide anion (O2-•) or alkylperoxide radicals (ROO•).
Katalog # CAS Nummer Summenformel Menge
sc-221946 652968-37-1 C₃₃H₃₇BrNO₂P 10 mg
Mn-cpx 3
A cell-permeable manganese complex of 7-hydroxyflavone that acts as a superoxide dismustase (SOD) mimetic and a neuroprotective agent against radical-induced damages. Shown to prevent the reduction of NBT by O2– • (IC₅₀ = 1.18 µM) and exhibit ~10 times higher potency than Trolox in inhibiting lipid peroxidation (IC5₅₀ = 6.15 µM) in vitro. Suppresses MAP (methamphetamine)-induced brain hypermotility in mice and shows protective effects against learning and memory impairment in a murine ischemic model in vivo.
Katalog # CAS Nummer Summenformel Menge
sc-221951 n.n. C₃₀H₂₀Cl₂MnO₆ 25 mg
Mn(III)TMPyP
A manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst.
Katalog # CAS Nummer Summenformel Menge
sc-221953 n.n. C₄₄H₃₆MnN₈•5Cl 10 mg/25 mg
Morin
Antioxidant flavonoid. Shows anti-proliferative and antitumor properties. Induces apoptosis. Induces cell cycle arrest at the G2/M phase. Anti-inflammatory compound. Suppresses NF-κB activation. Induces lipid peroxidation and DNA strand breaks.
Katalog # CAS Nummer Summenformel Menge
sc-205955 654055-01-3 C₁₅H₁₀O₇•xH₂O 1 g
Myeloperoxidase Inhibitor-I
Benzoic acid hydrazide analog acting as an irreversible and specific inhibitor of the peroxidation activity of MPO. Shows no effect in inhibition of catalase or glutathione peroxidase activities. Shows no effect on the production of superoxide by neutrophils. Shown to inhibit H2O2-induced apoptosis in HL-60.
Katalog # CAS Nummer Summenformel Menge
sc-204107 5351-17-7 C₇H₉N₃O 1 g
N-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-L-alanine, methyl ester
Inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits; exhibits antioxidant activity, inhibiting copper-mediated oxidation of low-density lipoprotein.
Katalog # CAS Nummer Summenformel Menge
sc-205398 778624-05-8 C₁₃H₁₅NO₅ 5 mg/10 mg
N-[3',4'-Dihydroxy-(E)-cinnamoyl]-3-hydroxy-L-tyrosine
An antioxidant isolated from the polyphenolic portion of Theobroma cacao L.; a potentially useful antioxidant and antiradical compound.
Katalog # CAS Nummer Summenformel Menge
sc-212046 53755-02-5 C₁₈H₁₇NO₇ 50 mg
N-tert-Butyl-a-phenylnitrone
Katalog # CAS Nummer Summenformel Menge
sc-202722 3376-24-7 C₁₁H₁₅NO 500 mg
(±)-Naringenin
Antioxidant flavonoid. Induces apoptosis. Stimulates DNA repair following oxidative damage. Inhibits PI3-kinase.
Katalog # CAS Nummer Summenformel Menge
sc-203155 67604-48-2 C₁₅H₁₂O₅ 1 g
Neobavaisoflavone
An isoflavanone derivative that has been reported to display anti-fungal and anti-proliferative capabilities. Also shown to prevent platelet aggregation in rabbit platelets.
Katalog # CAS Nummer Summenformel Menge
sc-202728 41060-15-5 C₂₀H₁₈O₄ 1 mg
Neohesperidin dihydrochalcone
A flavonoid sweetening agent with potent antioxidant activity.
Katalog # CAS Nummer Summenformel Menge
sc-219345 20702-77-6 C₂₈H₃₆O₁₅ 1 g/5 g
Nobiletin
A flavanoid with antioxidant and anti-inflammatory properties documented to suppress NOS2, COX-2, MMP-1, -3 and -9; expression; down regulation of ERK 1, ERK 2, c-Jun and Stat3; attenuate NF-κB transcriptional activation, and NO and PGE₂ production.
Katalog # CAS Nummer Summenformel Menge
sc-202733 478-01-3 C₂₁H₂₂O₈ 10 mg
PDM 2
A potential therapeutic for the treatment for dioxin and other aryl hydrocarbon poisonings.
Katalog # CAS Nummer Summenformel Menge
sc-205428 688348-25-6 C₁₄H₉Cl₃ 10 mg/50 mg
Pelargonidin chloride
Antioxidant flavonoid. Nitric oxide scavenger.
Katalog # CAS Nummer Summenformel Menge
sc-202761 134-04-3 C₁₅H₁₁O₅Cl 5 mg
Pentafluorobenzenesulfonyl fluorescein
Katalog # CAS Nummer Summenformel Menge
sc-205429 728912-45-6 C₂₆H₁₁F₅O₇S 1 mg/5 mg
Peonidin chloride
A methoxy anthocyanidin compound that exhibits antiinflammatory.
Katalog # CAS Nummer Summenformel Menge
sc-202762 134-01-0 C₁₆H₁₃O₆Cl 5 mg
Piperine
An alkaloid from black pepper that shows chemopreventive, cytotoxic, anti-inflammatory, and antioxidant effects. It is suggested that piperine exerts its chemopreventive effect by augmenting antioxidant defense system and modulating lipid peroxidation.
Katalog # CAS Nummer Summenformel Menge
sc-205809 94-62-2 C₁₇H₁₉NO₃ 5 g/25 g
Pirfenidone
A small molecule antifibrotic agent, demonstrated to suppress collagen production. An antioxidant and radical scavenger.
Katalog # CAS Nummer Summenformel Menge
sc-203663 53179-13-8 C₁₂H₁₁NO 10 mg/50 mg
Probucol
Antioxidant, anti-inflammatory and hypocholesterolemic agent. Inhibits atherogenesis in genetically hypercholesterolemic rabbits (Watanabe) and attenuates ischemia/reperfusion-induced cardiomyocyte apoptosis.
Katalog # CAS Nummer Summenformel Menge
sc-203666 23288-49-5 C₃₁H₄₈O₂S₂ 100 mg/1 g
Procysteine
A glutathione (GSH) precursor that links GSH synthesis and metabolism. Also found to stimulate expression of insulin-like growth factor-1, cariotrophin-1, and ciliary neurotrophic factor.
Katalog # CAS Nummer Summenformel Menge
sc-200811 19771-63-2 C₄H₅NO₃S 1 g
Protocatechuic Acid
A phenolic acid antioxidant present in fruits, vegetables and nuts. Found to be an efficacious chemopreventive agent in several carcinogenesis models.
Katalog # CAS Nummer Summenformel Menge
sc-205818 99-50-3 C₇H₆O₄ 25 g/50 g
Pterostilbene, Pterocarpus marsupium
Shown to be a free radical scavenger as well as a moderate inhibitor of Cox-1. Also has been reported to induce PPARα which causes a decrease in glucose concentrations.
Katalog # CAS Nummer Summenformel Menge
sc-203223 537-42-8 C₁₆H₁₆O₃ 10 mg
PTMIO, free radical
An imidazoline-based N-oxyl radical compound. Used as a primary standard for ESR absorption and as an SOD mimetic in oxidative stress studies.
Katalog # CAS Nummer Summenformel Menge
sc-202783 39753-69-0 C₁₃H₁₇N₂O 50 mg/250 mg
Puerarin
A flavonoid derivative from the traditional oriental medicine, Ge-gen. Purarin has potential antioxidant activity and impairs CYP catalyzed drug metabolism.
Katalog # CAS Nummer Summenformel Menge
sc-202301 3681-99-0 C₂₁H₂₀O₉ 5 mg/10 mg
Pyocyanin
Shown to accelerate neutrophil apoptosis in vitro, resulting in resolution of acute inflammation, that is beneficial for bacterial survival.
Katalog # CAS Nummer Summenformel Menge
sc-205475 85-66-5 C₁₃H₁₀N₂O 5 mg/10 mg
Pyrrolostatin
Potent inhibitor of lipid peroxidation (IC₅₀=49µM; inhibition of lipid peroxidation in rat brain homogenate). Improves angiogenesis and a free radical scavenger.
Katalog # CAS Nummer Summenformel Menge
sc-204869 144314-68-1 C₁₅H₂₁NO₂ 100 µg/1 mg
rac Terpinen-4-ol
Is an antiseptic. Shows antioxidant effects.
Katalog # CAS Nummer Summenformel Menge
sc-212744 562-74-3 C₁₀H₁₈O 1 mg
Rebamipide
An antiulcer agent that enhances mucosal resistance, increases endogenous prostaglandin in gastric mucosa, and also scavenges oxygen-derived free radicals and inhibits their production.
Katalog # CAS Nummer Summenformel Menge
sc-205835 90098-04-7 C₁₉H₁₅ClN₂O₄ 1 g/5 g
Ro 48-8071
An inhibitor of oxidosqualene cyclase that has low-density lipoprotein (LDL) cholesterol lowering activity similar to the HMG-CoA inhibitor simvastatin.
Katalog # CAS Nummer Summenformel Menge
sc-205492 161582-11-2 C₂₃H₂₇BrFNO₂ 5 mg/10 mg
Rutin trihydrate
Antioxidant flavonoid and Nitric oxide (NO) scavenger.
Katalog # CAS Nummer Summenformel Menge
sc-204897 153-18-4 C₂₇H₃₀O₁₆•3H₂O 5 g/50 g/100 g
Sauchinone
Diastereomeric lignan with cytoprotective and antioxidant activities in cultured hepatocytes. This is an inhibitor of LPS-inducible iNOS (NOS II), TNF-α and COX-2 expression in macrophages through suppression of IκBα phosphorylation and p65 nuclear translocation and of C/EBP and/or AP-1 activation, which may have constitutive anti-inflammatory effects. This is also a suppressor of NF-κB by inhibiting transactivation activity of the RelA subunit and inhibits staurosporine-induced apoptosis. Inhibits RANKL-induced osteoclastogenesis by reducing ROS generation.
Katalog # CAS Nummer Summenformel Menge
sc-222288 n.n. C₂₀H₂₀O₆ 1 mg/5 mg
Silybin
Major active constituent of silymarin. Anti-inflammatory, cytoprotective and anti-cancer compound. Shows chemopreventive effect against skin cancer. Inhibits MAPK.
Katalog # CAS Nummer Summenformel Menge
sc-202812 22888-70-6 C₂₅H₂₂O₁₀ 1 g/5 g
SOTS-1
An azo-compound that can be thermally decomposed in aqueous solution to create superoxide radical anion at a constant, controlled rate.
Katalog # CAS Nummer Summenformel Menge
sc-205511 223507-96-8 C₁₆H₁₄N₂O₆ 500 µg/1 mg
(±)-Sulfinpyrazone
A free radical scavenger that is an inhibitor of organic anion transporters and an effective uricosuric drug.
Katalog # CAS Nummer Summenformel Menge
sc-202822 57-96-5 C₂₃H₂₀N₂O₃S 1 g
(+)-Taxifolin
A flavanon compound which modulates chemopreventive genes through activation of the ARE.
Katalog # CAS Nummer Summenformel Menge
sc-202829 17654-26-1 C₁₅H₁₂O₇ 10 mg/50 mg
(±)-Taxifolin
Antioxidant flavonoid.
Katalog # CAS Nummer Summenformel Menge
sc-202828 480-18-2 C₁₅H₁₂O₇ 10 mg/50 mg
TEMPOL
A superoxide dismutase mimetic that belongs to a class of non-thiol-containing radiation protectors, with the ability to permeate the membrane, and restore the effects of TNF-α.
Katalog # CAS Nummer Summenformel Menge
sc-200825 2226-96-2 C₉H₁₈NO₂ 1 g
Tiliroside
Shown to display anti-complement activity as well as anti-proliferative effects. Has also been noted to suppress serum GPT and GOT elevations in D-GaIN/LPS-induced murine liver injury.
Katalog # CAS Nummer Summenformel Menge
sc-202364 20316-62-5 C₃₀H₂₆O₁₃ 1 mg
Tocopherylquinone, d-alpha
This compound is a vitaman E oxidation product, and an alpha-tocopherol oxidation product. It displays antioxidant activities after reduction to tocopherylhydroquinone.
Katalog # CAS Nummer Summenformel Menge
sc-200821 7559-04-8 C₂₉H₅₀O₃ 20 mg/100 mg
Trihydroxyethylrutin
A flavanoid derivative which protects membranes from oxidative damage produced by neutrophils and &gamma radiation which have deleterious effects on DNA.
Katalog # CAS Nummer Summenformel Menge
sc-203301 7085-55-4 C₃₃H₄₂O₁₉ 5 g/25 g
Trolox
An antioxidant derived from water-soluble vitamin E, with oxygen quenching activity, and the ability to block lipid peroxidation, cytotoxicity, and apoptosis.
Katalog # CAS Nummer Summenformel Menge
sc-200810 53188-07-1 C₁₄H₁₈O₄ 500 mg
U 82836E
Free radical scavenger and antioxidant; second generation lazaroid inhibitor of iron-dependent lipid peroxidation (IC₅₀ = 1.5 μM). Shows neuroprotective activity in a mouse head injury model (MHI) and causes a reduction in cyanide-induced cell death in rat cortical neurons.
Katalog # CAS Nummer Summenformel Menge
sc-204360 137018-55-4 C₃₀H₄₄N₆O₂.2HCl 50 mg
Uric acid
Katalog # CAS Nummer Summenformel Menge
sc-213135 69-93-2 C₅H₄N₄O₃ 25 g/100 g
Vialinin A
A terphenyl compound; potently inhibits the release of TNF-α, IL-4, β-hexosaminidase and CCL2 (MCP-1) from IgE-stimulated RBL-2H3 mast cells.
Katalog # CAS Nummer Summenformel Menge
sc-205539 858134-23-3 C₃₄H₂₆O₈ 1 mg/5 mg
Zeaxanthin
A dihydroxy carotenoid that contains anti-inflammatory and antioxidant properties. Contains scavenging capacity for O₂^-, HO^-, and H₂O₂.
Katalog # CAS Nummer Summenformel Menge
sc-205544 144-68-3 C₄₀H₅₆O₂ 500 µg/1 mg