Anticancer Reagents

2-Hydroxy-flutamide
Metabolite of flutamide found to inhibit the proliferation of estradiol-induced growth of MCF-7 breast cancer cells.
Katalog # CAS Nummer Summenformel Menge
sc-205574 52806-53-8 C₁₁H₁₁F₃N₂O₄ 10 mg/25 mg
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester
Used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, prostatic carcinoma and other hyperandrogenetic related disorders.
Katalog # CAS Nummer Summenformel Menge
sc-206677 103335-41-7 C₂₀H₂₉NO₃ 10 mg
4-Phenylbutyl isothiocyanate
Synthetic phenyl alkyl isothiocyanate that has displayed induction of Phase II detoxifying enzymes. Also inhibits chemically induced carcinogenesis.
Katalog # CAS Nummer Summenformel Menge
sc-205582 61499-10-3 C₁₁H₁₃NS 1 g/5 g
6-Chloroimidazo[1,2-b]pyridazine-2-carboxylic Acid
A pyridazine derivative exhibiting antihistaminic or eosinophil chemotaxis-inhibiting activity.
Katalog # CAS Nummer Summenformel Menge
sc-207105 14714-24-0 C₇H₄ClN₃O₂ 500 mg
6-O-Methyl-d3-guanine
Used as an antitumor agent.
Katalog # CAS Nummer Summenformel Menge
sc-210545 50704-43-3 C₆H₄D₃N₅O 5 mg
6-Thioguanine
Chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein.
Katalog # CAS Nummer Summenformel Menge
sc-205587 154-42-7 C₅H₅N₅S 250 mg/500 mg
9-Aminocamptothecin
An active derivative of camptothecin, which belongs to the general group of chemotherapy drugs called topoisomerase inhibitors.
Katalog # CAS Nummer Summenformel Menge
sc-205615 91421-43-1 C₂₀H₁₇N₃O₄ 10 mg/25 mg
AM 114
Displays anticancer activity. Has been shown to inhibit cell growth in human colon cancer HCT116 p53+/+ cells (IC50 = 1.49 μM). Inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50 ~ 1 μM).
Katalog # CAS Nummer Summenformel Menge
sc-291884 n.n. C₂₀H₂₁B₂NO₅ 10 mg/50 mg
α-Hydroxy Tamoxifen
A metabolite of the chemotherapeutic drug, Tamoxifen. Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.
Katalog # CAS Nummer Summenformel Menge
sc-207230 97151-02-5 C₂₆H₂₉NO₂ 10 mg
(±)Amethopterin hydrate
Folic acid antagonist and potent anticancer agent. Blocks DNA synthesis by blocking the production of tetrahydrofolate covactors required for the synthesis of thymidine. Actively transported into cells by the folate transporter.
Katalog # CAS Nummer Summenformel Menge
sc-214534 60388-53-6 (anhydrous) C₂₀H₂₂N₈O₅•xH₂O 25 mg/100 mg
Biochanin A
An isoflavone with antiproliferative and anti-inflammatory properties. Found to prevent phosphorylation of IκBα.
Katalog # CAS Nummer Summenformel Menge
sc-205603 491-80-5 C₁₆H₁₂O₅ 100 mg/250 mg
Carveol
A mixture of isomers. A terpene that inhibits mammary carcinogenesis.
Katalog # CAS Nummer Summenformel Menge
sc-205623 99-48-9 C₁₀H₁₆O 5 g/25 g
Clofarabine
A purine nucleoside analogue that is a lipophilic derivative of 2-Chloro-2'-deoxyadenosine. It has increased resistance to deamination and phosphorolysis compared to similar compounds.
Katalog # CAS Nummer Summenformel Menge
sc-278864 123318-82-1 C₁₀H₁₁ClFN₅O₃ 10 mg/50 mg
Clomiphene Citrate
A selective estrogen receptor modulator. Used as an antileukemic drug which kills cells by apoptosis mediated by oxidative stress and the activation of PKC.
Katalog # CAS Nummer Summenformel Menge
sc-205636 50-41-9 C₂₆H₂₈ClNO•C₆H₈O₇ 1 g/5 g
Crotamiton
An acaricide and that has action against scabies with antipruritic and marked antibacterial properties.
Katalog # CAS Nummer Summenformel Menge
sc-205639 483-63-6 C₁₃H₁₇NO 25 g/100 g
Diflunisal
NSAID analgesic with an unusually long duration of action. Recently found to exhibit anti-proliferative effects against colon adenocarcinoma cells.
Katalog # CAS Nummer Summenformel Menge
sc-205649 22494-42-4 C₁₃H₈F₂O₃ 5 g/10 g
Droloxifene
A phenolic analog of tamoxifen which is undergoing clinical trials for the treatment of metastatic breast cancer.
Katalog # CAS Nummer Summenformel Menge
sc-205660 82413-20-5 C₂₆H₂₉NO₂ 25 mg/100 mg
(E)-FeCp-oxindole
A selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 214 nM). Has been shown to display anticancer activity (IC50< 1 μM against B16 murine melanoma lines). A geometric isomer of (Z)-FeCP-oxindole.
Katalog # CAS Nummer Summenformel Menge
sc-285483 n.n. C₁₉H₁₅FeNO 10 mg
Enalapril
An antihypertensive agent known to reduce the incidence of vascular dementia and Alzheimer's disease. Found to have a potential for colon cancer prevention.
Katalog # CAS Nummer Summenformel Menge
sc-205664 75847-73-3 C₂₀H₂₈N₂O₅ 1 g/5 g
Erysolin
Shown to increase the amount of daunomycin and vinblastine in PANC-1 cells. Daunomycin and vinblastine is known to act as substrates for enzymes that assisted in drug-resistance of human cancer cell lines.
Katalog # CAS Nummer Summenformel Menge
sc-205679 504-84-7 C₆H₁₁NO₂S₂ 25 mg/50 mg
ES 936
Katalog # CAS Nummer Summenformel Menge
sc-362737 192820-78-3 C₁₈H₁₆N₂O₆ 10 mg/50 mg
Estriol
Estradiol metabolite was found to prevent bone loss in osteoporotic rats and post menopausal women. Provides protection against mammary carcinogenisis and urogenital tract aging.
Katalog # CAS Nummer Summenformel Menge
sc-205682 50-27-1 C₁₈H₂₄O₃ 100 mg/500 mg
Famotidine
An antiulcerative agent that has an immunomodulating effect. Successful in the prevention and control of chemotherapy-induced gastric mucosal injury.
Katalog # CAS Nummer Summenformel Menge
sc-205691 76824-35-6 C₈H₁₅N₇O₂S₃ 500 mg/1 g
Fotemustene
A nitrosourea alkylating agent that is being investigated for use in melanoma treatment.
Katalog # CAS Nummer Summenformel Menge
sc-205703 92118-27-9 C₉H₁₉ClN₃O₅P 5 mg/25 mg
Hesperidin
A flavonoid which has been found to be a potent chemopreventive agent in oral,urinary bladder, and colon carcinogenesis in animal models.
Katalog # CAS Nummer Summenformel Menge
sc-205711 520-26-3 C₂₈H₃₄O₁₅ 25 g/100 g
Iberin
May induce phase II detoxification enzymes and protect against chemical carcinogenesis.
Katalog # CAS Nummer Summenformel Menge
sc-205718 505-44-2 C₅H₉NOS₂ 10 mg/25 mg
Iberverin
May induce phase II detoxification enzymes and protect against chemical carcinogenesis.
Katalog # CAS Nummer Summenformel Menge
sc-205719 505-79-3 C₅H₉NS₂ 25 mg/50 mg
JS-2190
P-glycoprotein (Pgp) and MRP1 inhibitors. Results obtained with the calcein assay protocol [1] indicate that JS-2190 is efficiently taken up by living cells.
Katalog # CAS Nummer Summenformel Menge
sc-221784 n.n. C₃₀H₄₅N₃O₆ 5 mg
JW 480
Katalog # CAS Nummer Summenformel Menge
sc-362753 n.n. C₂₂H₂₃NO₂ 10 mg/50 mg
L-Deoxyalliin
Water-soluble organosulfur obtained from garlic. A proven candidate for chemoprevention in a clinical trial.
Katalog # CAS Nummer Summenformel Menge
sc-205728 21593-77-1 C₆H₁₁NO₂S 1 g/5 g
Lestaurtinib
Used in the treatment of pancreatic cancer and acute myelogenous leukaemia (AML).
Katalog # CAS Nummer Summenformel Menge
sc-218657 111358-88-4 C₂₆H₂₁N₃O₄ 0.5 mg/5 mg
Lorglumide Sodium
A specific cholecytokinin receptor antagonist which inhibits the effects of cholecytokinin on pancreatic growth and the development of pancreatic lesions and chemically induced carcinogenesis of the pancreas in rats.
Katalog # CAS Nummer Summenformel Menge
sc-205734 97964-56-2 C₂₂H₃₁Cl₂N₂NaO₄ 25 mg/100 mg
p-Xyleneselenocyanate
A synthetic organoselenium chemopreventive agent. Found to inhibit chemically induced carcinogenesis in the mammary glands, colon and lung of laboratory animals.
Katalog # CAS Nummer Summenformel Menge
sc-205786 85539-83-9 C₁₀H₈Se₂N₂ 100 mg/250 mg
Prednisolone
A glucocorticoid with anti-inflammatory and immuno-suppressive activity in rabbits. It induces apoptosis in colon cancer cell lines and eosinophils. Research shows that predinisolone in combination with TNP-470 may be a very effective drug for angiosarcoma treatment.
Katalog # CAS Nummer Summenformel Menge
sc-205815 50-24-8 C₂₁H₂₈O₅ 1 g/5 g
Protopanaxadiol
Ginseng saponin enhances axonal and dendritic formation activity. Shown to have characteristic effects on the proliferation of human leukemia cells.
Katalog # CAS Nummer Summenformel Menge
sc-205819 7755-01-3 C₃₀H₅₂O₃ 5 mg/10 mg
Retinyl palmitate
A vitamin A analog that inhibits cell proliferation and induces cell differentiation. Effective in lung cancer chemoprevention.
Katalog # CAS Nummer Summenformel Menge
sc-205836 79-81-2 C₃₆H₆₀O₂ 25 g/100 g
Reversin 121
Selective high affinity inhibitor of P-glycoprotein (MDR1).
Katalog # CAS Nummer Summenformel Menge
sc-205969 n.n. C₃₄H₄₇N₃O₉ 5 mg
Rhein
Induces apoptosis in cancer cell lines and inhibits transforming growth factor beta1 induced plasminogen activator inhibitor-1 in endothelial cells.
Katalog # CAS Nummer Summenformel Menge
sc-205837 478-43-3 C₁₅H₈O₆ 100 mg/500 mg
(S)-10-Hydroxycamptothecin
Camptothecin derivative that inhibits DNA topoisomerase I (for cancer therapy) by enacting strand breaks in chromosomal DNA and inducing apoptosis.
Katalog # CAS Nummer Summenformel Menge
sc-205614 19685-09-7 C₂₀H₁₆N₂O₅ 25 mg/100 mg
Ticlopidine Hydrochloride
A platelet aggregation inhibitor capable of inducing apoptosis in various cancer cell lines. Its effects on platelet aggregation may be the result of inhibition of VEGF.
Katalog # CAS Nummer Summenformel Menge
sc-205861 53885-35-1 C₁₄H₁₄ClNS•HCl 1 g/5 g
Toremifene
A chlorinated tamoxifen analogue which competes with estradiol for estrogen receptors and has growth inhibitory effects on MCF-7 breast cancer cells. The compound causes growth inhibition of estrogen-sensitive breast cancer cells by inducing some cells to undergo apoptosis and by inhibiting other cells from entering mitosis.
Katalog # CAS Nummer Summenformel Menge
sc-205868 89778-26-7 C₂₆H₂₈ClNO 500 mg/1 g
Vidarabine
Anti-leukemic agent. Neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes.
Katalog # CAS Nummer Summenformel Menge
sc-205881 5536-17-4 C₁₀H₁₃N₅O₄ 100 mg/500 mg
Vincristine N-Oxide
Potential treatment for hyperproliferative disorders.
Katalog # CAS Nummer Summenformel Menge
sc-213156 947527-73-3 C₄₆H₅₆N₄O₁₁ 2.5 mg
Vinorelbine base
Member of vinca-alkaloid. Used in the treatment of anthracycline-resistent advanced breast cancer. Also recommended for bronchial cancer treatment.
Katalog # CAS Nummer Summenformel Menge
sc-205885 71486-22-1 C₄₅H₅₄N₄O₈ 1 mg/5 mg
(Z)-FeCP-oxindole
A selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 220 nM). Has been shown to display anticancer activity (IC50< 1 μM against B16 murine melanoma lines). A geometric isomer of (E)-FeCP-oxindole.
Katalog # CAS Nummer Summenformel Menge
sc-286956 n.n. C₁₉H₁₅FeNO 10 mg