Activators - Other

• 1,1-Dimethylbiguanide, Hydrochloride
  An antihyperglycemic biguanide that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202000	1115-70-4	C4H11N5 ·HCl	1 g/5 g

• 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic Monophosphate sodium salt
  A cell-permeable potent activator of the Epac cAMP receptor, that does not affect PKA, making this potentially useful to discriminate between Epac and PKA-mediated effects.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202028	510774-50-2	C17H16CIN5O6PS ·Na	1 mg/5 mg

• 12-Deoxyphorbo 13-Angelate 20-Acetate
  Weak tumor promoter (mouse skin), but moderately strong irritant

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-287294	25090-72-6	C27H36O7	1 mg

• A 769662
  An AMP-activated protein kinase (AMPK) activator that mimics the function of AMP on AMPK β-1 by allosteric activation and the inhibition of dephosphorylation of AMPK.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203790	844499-71-4	C20H12N2O3S	10 mg/50 mg

• Adenosine 3′,5′-cyclic Monophosphorothioate,8-Bromo-, Sp-Isomer,Sodium Salt
  A potent cell-permeable, metabolically-stable activator of cAMP-dependent protein kinase (PKA).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-221215	n.n.	C10H10BrN5O5PS ·Na	5 µmol

• AICA-Riboside, 5′-Phosphate
  A monophosphorylated analog of the membrane permeable AICA-Riboside that activates AMPK.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202448	3031-94-5	C9H15N4O8P	50 mg

• AM 580
  A selective retinoic acid analog, which is useful in vitro as a RARα agonist. This compound inhibits tumor proliferation, via reducing the level of RARγ.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203505	102121-60-8	C22H25NO3	5 mg/25 mg

• AMPK Activator
  AMP-activated protein kinase (AMPK) Activator is a furancarboxylic acid derivative that can permeate the cell and partially inhibit the mitochondrial complex I.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203819	849727-81-7	C22H21FO4	5 mg

• CD 1530
  Potent and selective RARg agonist

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203871	107430-66-0	C27H26O3•xH2O	10 mg/50 mg

• CD 3254
  A selective RXRα agonist which is reported to not exhibit activity at RARα. RARβ or RARγ receptors.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-358786	196961-43-0	C24H28O3•xH2O	10 mg/50 mg

• CH 55
  A highly potent, synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203884	110368-33-7	C24H28O3	10 mg/50 mg

• CITCO
  Cell-permeable imidazothiazole compound. Potent and selective agonist for the human orphan nuclear constitutive androstane receptor (CAR).

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202544	338404-52-7	C19H12Cl3N3OS	5 mg

• Cord Factor
  Immunomodulatory compound. Induces activation of macrophages independent of TLR2 or TLR4.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202555	61512-20-7	n.n.	1 mg

• CTPB
  A membrane-impermeable amide derivative that is an activator of p300 histone acetyltransferase activity. Shown to enhance p300 HAT-dependent transcriptional activation.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202558	586976-24-1	C31H43ClF3NO2	1 mg/5 mg

• Glucocorticoid Receptor Modulator, CpdA
  A cell-permeable aziridine precursor that acts as a nonsteroidal glucocorticoid receptor ligand with a binding affinity that is 4-fold higher than that of Dexamethasone.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-221677	n.n.	C11H14ClNO2 ·HCl	25 mg

• Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt
  G-protein-activating GTP analog; more resistant to hydrolysis than GTP. Induces exocytosis in isolated mouse pancreatic acinar cells. Also reported to stimulate insulin release from pancreatic β-cells

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202639	94825-44-2	C10H12N5O13P3S ·4Li	10 mg

• Guanosine-3′,5′-cyclic Monophosphate, 8-(2-Aminophenylthio)-Sodium Salt
  Isozyme-selective activator of cGMP-dependent protein kinase 1a.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203335	144509-87-5	C16H16N6O7PS ·Na	5 µmol

• IBC 293
  A cell permeable Niacin triazolo derivative that is a selective agonist towards the human orphan G-protein-coupled receptor GPR109b/HM74.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203079	306935-41-1	C10H11N3O2	25 mg

• ITE

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-361214	448906-42-1	C14H10N2O3S	10 mg

• Kahweol acetate
  Inducer of glutathione S-transferase.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-228383	81760-47-6	C22H28O4	10 mg/25 mg

• L-JNKi 1 trifluoroacetate salt
  

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-300882	n.n.	C164H286N66O40•xC2HF3O2	1 mg

• m-3M3FBS
  Shown to stimulate calcium concentration increase in neutrophils by direct activation of PLC. Also has been reported to up-regulate Bax, down-regulate Bcl-2, and release Cytochrome c.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202217	200933-14-8	C16H16F3NO2S	10 mg

• Methyl α-Bromo-2-chlorophenylacetate

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-207877	85259-19-4	C9H8BrClO2	250 mg

• Monosodium urate (crystals)
  A cell permeable inflammatory compound that engages caspase-1-activiating cryopyrin inflammasome leading to the production of IL-1β and IL-18.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202711	1198-77-2	C5H3N4O3•Na	2 mg

• N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253087	78832-65-2	C23H32N4O7	5 mg/25 mg

• N-Hippuryl-His-Leu hydrate
  Isolation of human liver angiotensin-converting enzyme by chromatofocusing.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253112	207386-83-2	C21H27N5O5•xH2O	250 mg

• Naphthol AS-TR phosphate disodium salt
  Substrate for the histochemical demonstration of acid and alkaline phosphatase.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253179	4264-93-1	C18H13ClNNa2O5P	100 mg/1 g

• O-3M3FBS
  Inactive analog of m-3M3FBS . Used as a negative control.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-204142	313981-55-4	C16H16F3NO2S	10 mg

• S-Benzyl-L-cysteine p-nitroanilide
  A substrate used for the assay of cystyl-aminopeptidase (oxytocinase), EC 3.4.11.3.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-253447	7436-62-6	C16H17N3O3S	100 mg

• SEW2871
  A selective agonist of EDG-1 (Sphingosine-1-phosphate receptor 1; S1P1). Useful tool for elucidating the cardiovascular regulatory behaviors of EDG-1.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203251	256414-75-2	C20H10F6N2OS	5 mg/10 mg

• Scoparone
  A compound found in the herb, Yin Chin, that can up-regulate the expression and activate the constitutive androstane receptor (CAR) found in the liver.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202806	120-08-1	C11H10O4	25 mg

• SIRT1 Activator 3
  An activator of the enzyme SIRT1 that increases fluorescence by 233% in a SIRT1 activity assay, regulates the activity of the p53 tumor suppressor to inhibit apoptosis, and has shown activity in fat mobilization of adipocyte cells.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-222315	839699-72-8	C20H25N5O2	1 mg/5 mg

• T 0901317
  A nonsterol, cell-permeable benzenesulfonamide compound, that acts as a highly potent and selective agonist of the liver X receptor.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202824	293754-55-9	C17H12NSO3F9	10 mg

• TCPOBOP
  The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203291	76150-91-9	C16H8Cl4N2O2	25 mg

• TTNPB
  Synthetic stilbene analog of retinoic acid that acts as a potent retinoic acid receptor (RAR) agonist.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-203303	71441-28-6	C24H28O2	10 mg

• WAY 208466 dihydrochloride

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-361404	633304-27-5	C17H18FN3O2S ·2HCl	10 mg

• YC-1
  A compound that can activate platelet soluble guanylate cylcase (sGC) indepedent of nitric oxide activation.

  Katalog #	CAS Nummer	Summenformel	Menge
  sc-202856	170632-47-0	C19H16N2O2	1 mg